BCM Beauty Search Results

BEAUTY Search Results

BEAUTY (BLAST Enhanced Alignment Utility) is an enhanced version of the BLAST sequence database search tool. See the BEAUTY Help Page for a more detailed program description, as well as a description of the Protein Family and Conserved Regions databases used in this program. Provided by the Human Genome Sequencing Center, Baylor College of Medicine.

Reference:

Worley KC, Wiese BA, Smith RF. BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results. Genome Res 1995 Sep;5(2):173-84 Abstract

BLASTP 1.4.7MP [16-Oct-94] [Build 16:15:25 Mar 10 1999]

Reference: Altschul, Stephen F., Warren Gish, Webb Miller, Eugene W. Myers, and David J. Lipman (1990). Basic local alignment search tool. J. Mol. Biol. 215:403-10.

Query= query (709 letters)

EchoFilter:

> query
MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSR
CILFNRWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAE
GYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINS
ERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSV
DRQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQK
AFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIME
KLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKK
LISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSE
DVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQ
ARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILG
PCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEA
HPNLKIFRSESDDAERRKHWKYWEVAVERSKGWLKDIEGEHEQVLENFQ

Database: /local/dot5/sl_home/beauty/seqdb/blast-db/CRSeqAnnot.fa 78,469 sequences; 28,902,124 total letters.

Histogram:

     Observed Numbers of Database Sequences Satisfying
    Various EXPECTation Thresholds (E parameter values)

        Histogram units:      = 38 Sequences     : less than 38 sequences

 EXPECTation Threshold
 (E parameter)
    |
    V   Observed Counts-->
  10000 6319 2288 |============================================================
   6310 4031 1131 |=============================
   3980 2900 1053 |===========================
   2510 1847  520 |=============
   1580 1327  364 |=========
   1000  963  281 |=======
    631  682  218 |=====
    398  464  131 |===
    251  333   81 |==
    158  252   98 |==
    100  154   51 |=
   63.1  103   32 |:
 >>>>>>>>>>>>>>>>>>>>>  Expect = 50.0, Observed = 87  <<<<<<<<<<<<<<<<<
   39.8   71   14 |:
   25.1   57   15 |:
   15.8   42   10 |:
   10.0   32    6 |:
   6.31   26    5 |:
   3.98   21    4 |:
   2.51   17    0 |
   1.58   17    0 |
   1.00   17    0 |
   0.63   17    0 |
   0.40   17    0 |
   0.25   17    0 |
   0.16   17    0 |
   0.10   17    0 |
  0.063   17    0 |
  0.040   17    0 |
  0.025   17    1 |:

                                                                      Smallest
                                                                        Sum
                                                               High  Probability
Sequences producing High-scoring Segment Pairs:               Score  P(N)      N
 
sp|P32190|GLPK  GLYCEROL KINASE (ATP:GLYCEROL 3-PHOSPHOTRANSF  3729  0.0       1
gi|348167       glycerol kinase                                 314  1.1e-169 12
gi|515029       glycerol kinase                                 314  2.6e-169 12
sp|P32189|GLPK  GLYCEROL KINASE (ATP:GLYCEROL 3-PHOSPHOTRANSF   314  3.4e-130 10
sp|P18157|GLPK  GLYCEROL KINASE (ATP:GLYCEROL 3-PHOSPHOTRANSF   239  5.5e-120  9
pir||JN0606|gi  ATP-stimulated glucocorticoid-receptor transl   309  3.2e-119  9
gi|516124       glycerol kinase                                 313  4.4e-119  9
sp|P08859|GLPK  GLYCEROL KINASE (ATP:GLYCEROL 3-PHOSPHOTRANSF   258  1.1e-116  9
pir||S37661|gi  glycerol kinase - human                         314  8.0e-111  8
sp|P12011|GNTK  GLUCONOKINASE (GLUCONATE KINASE).               114  9.8e-23   6
gi|563951       Gluconate kinase                                104  2.6e-20   5
sp|P27155|XYLK  XYLULOSE KINASE (XYLULOKINASE).                  77  1.3e-13   4
gi|530434       glycerol kinase                                 138  3.9e-12   1
sp|P21939|XYLK  XYLULOSE KINASE (XYLULOKINASE).                  76  8.0e-09   6
sp|P29444|XYLK  XYLULOSE KINASE (XYLULOKINASE).                  74  1.8e-07   5
sp|P09099|XYLK  XYLULOSE KINASE (XYLULOKINASE).                  69  0.00029   5
sp|P11553|FUCK  FUCOKINASE.                                      48  0.019     4
gi|311895       heat shock protein                               66  0.96      1
pir||S24265|gi  intermediate filament protein, cytosolic - co    52  0.97      4
pir||S35562|gi  sex-determining protein SRY - common gibbon      64  0.97      2
pir||A48468|gi  Pfgrp=glucose-regulated stress protein homolo    53  0.97      2
pir||S10937|gi  35K protein - Human (fragment)                   64  0.98      1
pir||S35558|gi  sex-determining protein SRY - chimpanzee         64  0.994     1
pir||S35560|gi  sex-determining protein SRY - gorilla            64  0.994     1
sp|Q05066|SRY_  SEX-DETERMINING REGION Y PROTEIN (TESTIS-DETE    64  0.994     1
pir||S35561|gi  sex-determining protein SRY - orangutan          64  0.995     1
sp|P09424|MTLD  MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE.            54  0.999     2
pir||S35564|gi  sex-determining protein SRY - common marmoset    63  0.9994    1
sp|P18242|CATD  CATHEPSIN D PRECURSOR.                           42  0.9998    4
pir||S33210|gi  P69 antigen - Trypanosoma congolense             61  0.9999    2
sp|P22973|LEC2  ANTI-H(O) LECTIN II (UEA-II).                    51  0.9999    2
pir||S35563|gi  sex-determining protein SRY - baboon             62  0.99995   1
gi|552137       tropomyosin isoform 9E                           62  0.99998   1
gi|158693       tropomyosin isoform 9A                           62  0.99998   1
gi|158696       tropomyosin isoform 9D                           62  0.99998   1
gi|158694       tropomyosin isoform 34 (9B)                      62  0.999992  1
gi|158695       tropomyosin isoform 33 (9C)                      62  0.999993  1
gi|42039        mannitol-phosphate dehydrogenase (AA 1-382)      52  0.999993  2
prf||1615309A|  Ig lambda,anti-Rh(c)                             58  0.999998  2
gi|483472       leucine dehydrogenase                            44  0.999999  4
prf||1901184C|  xylB gene                                        48  0.999999  2
pir||A48592|gi  transferrin receptor protein - Chinese hamste    54  0.999999  2
sp|P12390|ACHN  NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, BETA    61  1.000000  1
sp|P38148|YB9T  PROBABLE PROTEIN-TYROSINE PHOSPHATASE YBR276C    61  1.000000  1
pir||S36105|gi  hgdC protein - Acidaminococcus fermentans        58  1.000000  2
pir||S35559|gi  sex-determining protein SRY - pygmy chimpanze    60  1.000000  1
gi|35076        N-myc protein                                    43  1.000000  3
gi|438458       likely N-terminal signal sequence; mature pro    53  1.000000  3
sp|P04198|MYCN  N-MYC PROTO-ONCOGENE PROTEIN.                    43  1.000000  3
gi|452510       phytochrome                                      51  1.000000  3

WARNING: Descriptions of 37 database sequences were not reported due to the limiting value of parameter V = 50.




Locally-aligned regions (HSPs) with respect to query sequence:

Locus_ID        Clus_ID
sp|P32190|GLPK  2503.7 |__________________________________________________
gi|348167       2503.7 |   ___    ______ ________ _____________ _____ ___ 
gi|515029       2503.7 |   _____  ______ ________ _____________ _____ ___ 
sp|P32189|GLPK  2503.7 |             ___ ________ _____________ _____ ___ 
sp|P18157|GLPK         |   ___   _______ _______ ______________ _____ ___ 
pir||JN0606|gi  2503.7 |   ___    ___    ____  __ _____________ _____ ___ 
gi|516124       2503.7 |   ___   ____    ____  __ _____________ _____ ___ 
sp|P08859|GLPK         |   ___ __ ______ ________ _____________ _____     
pir||S37661|gi  2503.7 |             ___ ________ _____________ ___       
sp|P12011|GNTK  2599.7 |   ____              ___ ____  ________ ____      
gi|563951       2599.7 |   ___               ___       ________ ____      
sp|P27155|XYLK  2599.7 |   ___         ___                _____  __       
gi|530434       2503.7 |                                  _____           
sp|P21939|XYLK  2599.7 |   ___    _______ __              _____  ___      
sp|P29444|XYLK  2599.7 |   ___         ___  ______        ____     __     
sp|P09099|XYLK  2599.7 |   ___               _____       _____   __       
sp|P11553|FUCK  5404.3 |   ___               ___            ___ ___ ____  
gi|311895       72.93  |                                       _____      
pir||S24265|gi  99.79  |___            ___            ___     ____        
pir||S35562|gi  228.48 |               ___                          ___   
pir||A48468|gi  72.93  |                                       ___   __   
pir||S10937|gi  228.48 |                                            ___   
pir||S35558|gi  228.48 |                                            ___   
pir||S35560|gi  228.48 |                                            ___   
sp|Q05066|SRY_  228.48 |                                            ___   
pir||S35561|gi  228.48 |                                            ___   
sp|P09424|MTLD  3338   |  _____                                ___        
pir||S35564|gi  228.48 |                                            ___   
sp|P18242|CATD  593.21 |___                     _   __           __       
pir||S33210|gi  72.93  |                                  __   _____      
sp|P22973|LEC2  1788   |               __                           ___   
pir||S35563|gi  228.48 |                                            ___   
gi|552137       81.92  |                                      _____       
gi|158693       81.92  |                                      _____       
gi|158696       81.92  |                                      _____       
gi|158694       81.92  |                                      _____       
gi|158695       81.92  |                                      _____       
gi|42039        3338   |  _____                                ___        
prf||1615309A|  58.118 |                    ___                     ____  
gi|483472       2224.8 |   _____                              _____     __
prf||1901184C|  2599.7 |   __          ___                                
pir||A48592|gi  2754.6 |                           ___           __       
sp|P12390|ACHN  89.83  |                                               __ 
sp|P38148|YB9T  12667.1|                   ____                           
pir||S36105|gi  7783.2 |   ___     __               _                     
pir||S35559|gi  228.48 |                                            ___   
gi|35076        275.42 |      __                              ___     __  
gi|438458       12426  |             ____      __                   __    
sp|P04198|MYCN  275.42 |      __                              ___     __  
gi|452510       1179.13|   ____                 ____                    __
Prosite Hits:                             _                 __            
                        __________________________________________________
Query sequence:        |          |          |         |          |       | 709
                       0        150        300       450        600
__________________
Prosite hits:
   FGGY_KINASES_1       FGGY family of carbohydrate kinases sign 258..270
   FGGY_KINASES_2       FGGY family of carbohydrate kinases sign 515..535
__________________

Note:In the alignments click on to_old

to return to the respective one line description, or (if available) on to_ent

to extract the entry from the database.

Use the and icons to retrieve links to Entrez:

E = Retrieve Entrez links (e.g., Medline abstracts, FASTA-formatted sequence reports).

R = Retrieve links to Related sequences (neighbors).
Use the

icon (if present) to retrieve links to the Sequence Retrieval System (SRS).

sp|P32190|GLPK_YEAST|gi|417068 GLYCEROL KINASE (ATP:GLYCEROL
            3-PHOSPHOTRANSFERASE) (GLYCEROKINASE) (GK).
            Length = 709

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6                    |   __       ____ _____    ___|
   Cluster 2503.7                                         |_ _   |

Local hits (HSPs):      __________________________________________________
Annotated Domains:         __     __ ____________ __________________      
                        __________________________________________________
Database sequence:     |          |          |         |          |       | 709
                       0        150        300       450        600
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 195..350
   PFAM                 FGGY: FGGY family of carbohydrate kinase 377..432
   PFAM                 FGGY: FGGY family of carbohydrate kinase 454..555
   PFAM                 FGGY: FGGY family of carbohydrate kinase 575..619
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 48..71
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 147..157
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 251..270
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 450..486
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 583..598
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 258..270
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 515..535
__________________


 Score = 3729 (1717.6 bits), Expect = 0.0, P = 0.0
 Identities = 709/709 (100%), Positives = 709/709 (100%)

Query:     1 MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSR 60
             MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSR
Sbjct:     1 MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSR 60

Query:    61 CILFNRWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAE 120
             CILFNRWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAE
Sbjct:    61 CILFNRWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAE 120

Query:   121 GYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINS 180
             GYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINS
Sbjct:   121 GYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINS 180

Query:   181 ERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSV 240
             ERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSV
Sbjct:   181 ERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSV 240

Query:   241 DRQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQK 300
             DRQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQK
Sbjct:   241 DRQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQK 300

Query:   301 AFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIME 360
             AFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIME
Sbjct:   301 AFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIME 360

Query:   361 KLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKK 420
             KLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKK
Sbjct:   361 KLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKK 420

Query:   421 LISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSE 480
             LISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSE
Sbjct:   421 LISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSE 480

Query:   481 DVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQ 540
             DVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQ
Sbjct:   481 DVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQ 540

Query:   541 ARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILG 600
             ARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILG
Sbjct:   541 ARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILG 600

Query:   601 PCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEA 660
             PCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEA
Sbjct:   601 PCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEA 660

Query:   661 HPNLKIFRSESDDAERRKHWKYWEVAVERSKGWLKDIEGEHEQVLENFQ 709
             HPNLKIFRSESDDAERRKHWKYWEVAVERSKGWLKDIEGEHEQVLENFQ
Sbjct:   661 HPNLKIFRSESDDAERRKHWKYWEVAVERSKGWLKDIEGEHEQVLENFQ 709


gi|348167 glycerol kinase
           Length = 524

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6               |    __         _ __  __  _     ___|
   Cluster 2503.7                                        |__ __ |

Local hits (HSPs):      ___________ _________________________________ ___ 
                        __________________________________________________
Database sequence:     |              |             |             |       | 524
                       0            150           300           450

 Score = 314 (144.6 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 60/100 (60%), Positives = 75/100 (75%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEGSVA+AGAV++WLRDNL +I  SE++  +A  V  S G  FVPAFSGL+APYW+P
Sbjct:   315 YYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEP 374

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
              AR  I G++QFT   HIA AA+E VCFQ R IL AM+ D
Sbjct:   375 SARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRD 414

 Score = 195 (89.8 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 36/56 (64%), Positives = 45/56 (80%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAF 433
             +PI GCLGDQSA++VGQ+ ++ G AK TYGTGCFLL NTG K + S HG LTT+A+
Sbjct:   251 VPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAY 306

 Score = 135 (62.2 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 26/43 (60%), Positives = 30/43 (69%)

Query:   255 LSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT 297
             LSTYFS  KLRW LDN     KA EE   +FGT+D+WLI+ LT
Sbjct:   145 LSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLT 187

 Score = 87 (40.1 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 16/34 (47%), Positives = 25/34 (73%)

Query:   304 SDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLI 337
             +DVTNASRT   N+ +L++D +L EF+GI   ++
Sbjct:   197 TDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEIL 230

 Score = 77 (35.5 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 11/23 (47%), Positives = 19/23 (82%)

Query:   195 MGIANMRETTILWSRRTGKPIVN 217
             +G++N RETT++W + TG+P+ N
Sbjct:    88 IGVSNQRETTVVWDKITGEPLYN 110

 Score = 76 (35.0 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 16/25 (64%), Positives = 20/25 (80%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADIL 599
             PLS L VDGGM+ +  +MQ+QADIL
Sbjct:   418 PLSHLQVDGGMTSNKILMQLQADIL 442

 Score = 71 (32.7 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 12/34 (35%), Positives = 22/34 (64%)

Query:   146 KFPKPGWVECHPQKLLVNVVQCLASSLLSLQTIN 179
             +FP+ GWVE  P+++L +V +C+  +   L  +N
Sbjct:    46 EFPREGWVEQDPKEILHSVYECIEKTCEKLGQLN 79

 Score = 59 (27.2 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 10/28 (35%), Positives = 19/28 (67%)

Query:    47 PLIASIDVGTTSSRCILFNRWGQDVSKH 74
             PL+ ++D GT+S+R ++FN    ++  H
Sbjct:    11 PLVGAVDQGTSSTRFLVFNSKTAELLSH 38

 Score = 44 (20.3 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query:   603 VKVRRSPTAECTALGAAIAANMA 625
             + V +    E TALGAA+AA  A
Sbjct:   444 IPVVKPSMPETTALGAAMAAGAA 466

 Score = 43 (19.8 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 8/28 (28%), Positives = 14/28 (50%)

Query:   667 FRSESDDAERRKHWKYWEVAVERSKGWL 694
             F  + +  E    +  W+ AV +S GW+
Sbjct:   487 FEPQINAEESEIRYSTWKKAVMKSMGWV 514

 Score = 42 (19.3 bits), Expect = 1.2e-45, Sum P(5) = 1.2e-45
 Identities = 7/15 (46%), Positives = 12/15 (80%)

Query:   411 FLLYNTGTKKLISQH 425
             FL++N+ T +L+S H
Sbjct:    25 FLVFNSKTAELLSHH 39

 Score = 40 (18.4 bits), Expect = 6.4e-26, Sum P(8) = 6.4e-26
 Identities = 6/14 (42%), Positives = 11/14 (78%)

Query:   466 VQWLRDNLRLIDKS 479
             ++WL DN+R + K+
Sbjct:   154 LRWLLDNVRKVQKA 167

 Score = 35 (16.1 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 6/12 (50%), Positives = 9/12 (75%)

Query:   339 MPEIVSSSQYYG 350
             +P + SSS+ YG
Sbjct:   230 LPNVRSSSEIYG 241

 Score = 34 (15.7 bits), Expect = 1.1e-169, Sum P(12) = 1.1e-169
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query:   246 LRQKTGLPL 254
             ++ KTGLPL
Sbjct:   137 VKSKTGLPL 145


gi|515029 glycerol kinase
           Length = 553

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6              |    __        __ _  ___ _     __ |
   Cluster 2503.7                                      |__ __ |

Local hits (HSPs):      __________  ___________________________________   
                        __________________________________________________
Database sequence:     |             |             |            |         | 553
                       0           150           300          450

 Score = 314 (144.6 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 60/100 (60%), Positives = 75/100 (75%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEGSVA+AGAV++WLRDNL +I  SE++  +A  V  S G  FVPAFSGL+APYW+P
Sbjct:   315 YYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEP 374

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
              AR  I G++QFT   HIA AA+E VCFQ R IL AM+ D
Sbjct:   375 SARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRD 414

 Score = 195 (89.8 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 36/56 (64%), Positives = 45/56 (80%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAF 433
             +PI GCLGDQSA++VGQ+ ++ G AK TYGTGCFLL NTG K + S HG LTT+A+
Sbjct:   251 VPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAY 306

 Score = 135 (62.2 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 26/43 (60%), Positives = 30/43 (69%)

Query:   255 LSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT 297
             LSTYFS  KLRW LDN     KA EE   +FGT+D+WLI+ LT
Sbjct:   145 LSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLT 187

 Score = 87 (40.1 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 16/34 (47%), Positives = 25/34 (73%)

Query:   304 SDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLI 337
             +DVTNASRT   N+ +L++D +L EF+GI   ++
Sbjct:   197 TDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEIL 230

 Score = 76 (35.0 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 16/25 (64%), Positives = 20/25 (80%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADIL 599
             PLS L VDGGM+ +  +MQ+QADIL
Sbjct:   418 PLSHLQVDGGMTSNKILMQLQADIL 442

 Score = 75 (34.5 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 11/23 (47%), Positives = 18/23 (78%)

Query:   195 MGIANMRETTILWSRRTGKPIVN 217
             +G++N RETT+ W + TG+P+ N
Sbjct:    88 IGVSNQRETTVAWDKITGEPLYN 110

 Score = 71 (32.7 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 12/34 (35%), Positives = 22/34 (64%)

Query:   146 KFPKPGWVECHPQKLLVNVVQCLASSLLSLQTIN 179
             +FP+ GWVE  P+++L +V +C+  +   L  +N
Sbjct:    46 EFPREGWVEQDPKEILHSVYECIEKTCEKLGQLN 79

 Score = 59 (27.2 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 10/28 (35%), Positives = 19/28 (67%)

Query:    47 PLIASIDVGTTSSRCILFNRWGQDVSKH 74
             PL+ ++D GT+S+R ++FN    ++  H
Sbjct:    11 PLVGAVDQGTSSTRFLVFNSRTAELLSH 38

 Score = 43 (19.8 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 10/14 (71%), Positives = 11/14 (78%)

Query:   612 ECTALGAAIAANMA 625
             E TALGAA+AA  A
Sbjct:   453 ETTALGAAMAAGAA 466

 Score = 43 (19.8 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 8/28 (28%), Positives = 14/28 (50%)

Query:   667 FRSESDDAERRKHWKYWEVAVERSKGWL 694
             F  + +  E    +  W+ AV +S GW+
Sbjct:   487 FEPQINAEESEIRYSTWKKAVMKSMGWV 514

 Score = 42 (19.3 bits), Expect = 3.2e-45, Sum P(5) = 3.2e-45
 Identities = 7/15 (46%), Positives = 12/15 (80%)

Query:   411 FLLYNTGTKKLISQH 425
             FL++N+ T +L+S H
Sbjct:    25 FLVFNSRTAELLSHH 39

 Score = 40 (18.4 bits), Expect = 3.6e-23, Sum P(7) = 3.6e-23
 Identities = 6/14 (42%), Positives = 11/14 (78%)

Query:   466 VQWLRDNLRLIDKS 479
             ++WL DN+R + K+
Sbjct:   154 LRWLLDNVRKVQKA 167

 Score = 35 (16.1 bits), Expect = 3.6e-152, Sum P(11) = 3.6e-152
 Identities = 6/12 (50%), Positives = 9/12 (75%)

Query:   339 MPEIVSSSQYYG 350
             +P + SSS+ YG
Sbjct:   230 LPHVRSSSEIYG 241

 Score = 34 (15.7 bits), Expect = 2.6e-169, Sum P(12) = 2.6e-169
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query:   246 LRQKTGLPL 254
             ++ KTGLPL
Sbjct:   137 VKSKTGLPL 145

 Score = 34 (15.7 bits), Expect = 5.0e-127, Sum P(10) = 5.0e-127
 Identities = 8/22 (36%), Positives = 12/22 (54%)

Query:    87 IGVSGLRRPSTAPARETPNAGD 108
             IG+S ++    +  RET  A D
Sbjct:    80 IGISNIKAIGVSNQRETTVAWD 101


sp|P32189|GLPK_HUMAN|gi|417067 GLYCEROL KINASE (ATP:GLYCEROL
            3-PHOSPHOTRANSFERASE) (GLYCEROKINASE) (GK).
            Length = 454

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6       |     ___           _ __   ___ __     ___ |
   Cluster 2503.7                                     |___ __  |

Local hits (HSPs):       ___  ______________________________________ ____ 
                        __________________________________________________
Database sequence:     |                |               |                || 454
                       0              150             300              450

 Score = 314 (144.6 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 60/100 (60%), Positives = 75/100 (75%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEGSVA+AGAV++WLRDNL +I  SE++  +A  V  S G  FVPAFSGL+APYW+P
Sbjct:   245 YYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEP 304

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
              AR  I G++QFT   HIA AA+E VCFQ R IL AM+ D
Sbjct:   305 SARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRD 344

 Score = 195 (89.8 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 36/56 (64%), Positives = 45/56 (80%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAF 433
             +PI GCLGDQSA++VGQ+ ++ G AK TYGTGCFLL NTG K + S HG LTT+A+
Sbjct:   181 VPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAY 236

 Score = 135 (62.2 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 26/43 (60%), Positives = 30/43 (69%)

Query:   255 LSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT 297
             LSTYFS  KLRW LDN     KA EE   +FGT+D+WLI+ LT
Sbjct:    69 LSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLT 111

 Score = 87 (40.1 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 16/34 (47%), Positives = 25/34 (73%)

Query:   304 SDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLI 337
             +DVTNASRT   N+ +L++D +L EF+GI   ++
Sbjct:   121 TDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEIL 154

 Score = 77 (35.5 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 11/23 (47%), Positives = 19/23 (82%)

Query:   195 MGIANMRETTILWSRRTGKPIVN 217
             +G++N RETT++W + TG+P+ N
Sbjct:    12 IGVSNQRETTVVWDKITGEPLYN 34

 Score = 76 (35.0 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 16/25 (64%), Positives = 20/25 (80%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADIL 599
             PLS L VDGGM+ +  +MQ+QADIL
Sbjct:   348 PLSHLQVDGGMTSNKILMQLQADIL 372

 Score = 44 (20.3 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query:   603 VKVRRSPTAECTALGAAIAANMA 625
             + V +    E TALGAA+AA  A
Sbjct:   374 IPVVKPSMPETTALGAAMAAGAA 396

 Score = 43 (19.8 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 8/28 (28%), Positives = 14/28 (50%)

Query:   667 FRSESDDAERRKHWKYWEVAVERSKGWL 694
             F  + +  E    +  W+ AV +S GW+
Sbjct:   417 FEPQINAEESEIRYSTWKKAVMKSMGWV 444

 Score = 40 (18.4 bits), Expect = 3.4e-14, Sum P(6) = 3.4e-14
 Identities = 6/14 (42%), Positives = 11/14 (78%)

Query:   466 VQWLRDNLRLIDKS 479
             ++WL DN+R + K+
Sbjct:    78 LRWLLDNVRKVQKA 91

 Score = 35 (16.1 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 6/12 (50%), Positives = 9/12 (75%)

Query:   339 MPEIVSSSQYYG 350
             +P + SSS+ YG
Sbjct:   154 LPNVRSSSEIYG 165

 Score = 34 (15.7 bits), Expect = 3.4e-130, Sum P(10) = 3.4e-130
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query:   246 LRQKTGLPL 254
             ++ KTGLPL
Sbjct:    61 VKSKTGLPL 69


sp|P18157|GLPK_BACSU|gi|121415 GLYCEROL KINASE (ATP:GLYCEROL
            3-PHOSPHOTRANSFERASE) (GLYCEROKINASE) (GK).
            Length = 496


Local hits (HSPs):      __________   _____________________________________
Annotated Domains:      _____  ______________________________________     
                        __________________________________________________
Database sequence:     |               |              |              |    | 496
                       0             150            300            450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 76..443
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 4..27
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 38..48
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 127..146
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 180..216
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 409..424
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 134..146
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 361..381
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 377..385
__________________


 Score = 239 (110.1 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 45/103 (43%), Positives = 64/103 (62%)

Query:   450 KPHFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYW 509
             K ++ALEGS+ VAG+ +QWLRD LR+   S      A  V  + GV  VPAF GL  PYW
Sbjct:   296 KVNYALEGSIFVAGSAIQWLRDGLRMFQDSSLSESYAEKVDSTDGVYVVPAFVGLGTPYW 355

Query:   510 DPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSDA 552
             D D R ++ G+++ TT  H  RA +E + +Q + +L AM +D+
Sbjct:   356 DSDVRGSVFGLTRGTTKEHFIRATLESLAYQTKDVLDAMEADS 398

 Score = 201 (92.6 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 36/84 (42%), Positives = 60/84 (71%)

Query:   254 LLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQKAFVSDVTNASRTG 313
             L+  YFS +K++W LDN     +  E+ +L+FGT+DTWLI++++  KA V+D +NASRT 
Sbjct:   130 LIDPYFSGTKVKWILDNVEGAREKAEKGELLFGTIDTWLIWKMSGGKAHVTDYSNASRTL 189

Query:   314 FMNLSTLKYDNELLEFWGIDKNLI 337
               N+  LK+D++LL+  G+ K+++
Sbjct:   190 MFNIYDLKWDDQLLDILGVPKSML 213

 Score = 175 (80.6 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 33/71 (46%), Positives = 46/71 (64%)

Query:   363 HDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLI 422
             H   +TV      +N+PI G  GDQ +++ GQ  ++ G  K TYGTGCF+L NTG K + 
Sbjct:   221 HVYAETVDYHFFGKNIPIAGAAGDQQSALFGQACFEEGMGKNTYGTGCFMLMNTGEKAIK 280

Query:   423 SQHGALTTLAF 433
             S+HG LTT+A+
Sbjct:   281 SEHGLLTTIAW 291

 Score = 84 (38.7 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 16/43 (37%), Positives = 25/43 (58%)

Query:   175 LQTINSERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVN 217
             L  I S    +G+   ++  +GI N RETT++W + TG P+ N
Sbjct:    56 LAVIASVISESGISASQIAGIGITNQRETTVVWDKDTGSPVYN 98

 Score = 77 (35.5 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 17/31 (54%), Positives = 22/31 (70%)

Query:    49 IASIDVGTTSSRCILFNRWGQDVSKHQIEYS 79
             I S+D GTTSSR ILFN+ G+ V   Q E++
Sbjct:     5 ILSLDQGTTSSRAILFNKEGKIVHSAQKEFT 35

 Score = 60 (27.6 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 12/24 (50%), Positives = 16/24 (66%)

Query:   576 LSVLAVDGGMSRSNEVMQIQADIL 599
             L  L VDGG  ++N +MQ Q D+L
Sbjct:   402 LKTLRVDGGAVKNNFLMQFQGDLL 425

 Score = 56 (25.8 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 12/29 (41%), Positives = 18/29 (62%)

Query:   142 EPTLKFPKPGWVECHPQKLLVNVVQCLAS 170
             E T  FP PGWVE +  ++  +V+  +AS
Sbjct:    33 EFTQYFPHPGWVEHNANEIWGSVLAVIAS 61

 Score = 45 (20.7 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 12/23 (52%), Positives = 13/23 (56%)

Query:   603 VKVRRSPTAECTALGAAIAANMA 625
             V V R    E TALGAA  A +A
Sbjct:   427 VPVERPEINETTALGAAYLAGIA 449

 Score = 41 (18.9 bits), Expect = 5.5e-120, Sum P(9) = 5.5e-120
 Identities = 8/24 (33%), Positives = 15/24 (62%)

Query:   665 KIFRSESDDAERRKHWKYWEVAVE 688
             K F  E ++ +R + +K W+ AV+
Sbjct:   467 KRFEPELEEEKRNELYKGWQKAVK 490

 Score = 34 (15.7 bits), Expect = 2.4e-22, Sum P(7) = 2.4e-22
 Identities = 5/12 (41%), Positives = 9/12 (75%)

Query:   462 AGAVVQWLRDNL 473
             +G  V+W+ DN+
Sbjct:   136 SGTKVKWILDNV 147


pir||JN0606|gi|484372 ATP-stimulated glucocorticoid-receptor translocation
            promoter protein - rat
            Length = 524

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6               |    __         _ __  __  _     ___|
   Cluster 2503.7                                        |__ __ |

Local hits (HSPs):      ________     _____   ________________________ ___ 
Annotated Domains:               __   __             _     ___            
                        __________________________________________________
Database sequence:     |              |             |             |       | 524
                       0            150           300           450
__________________

Annotated Domains:
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 148..160
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 378..398
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 102..109
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 307..315
__________________


 Score = 309 (142.3 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 59/100 (59%), Positives = 74/100 (74%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEGSVA+AGAV++WLRDNL +I  SE++  +A  V  S G  FVPAFS L+APYW+P
Sbjct:   315 YYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVPAFSALYAPYWEP 374

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
              AR  I G++QFT   HIA AA+E VCFQ R IL AM+ D
Sbjct:   375 SARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRD 414

 Score = 199 (91.7 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 36/56 (64%), Positives = 46/56 (82%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAF 433
             +PI GCLGDQSA++VGQ+ ++ G AK TYGTGCFLL NTG K + S+HG LTT+A+
Sbjct:   251 VPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGHKCVFSEHGLLTTVAY 306

 Score = 138 (63.6 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 26/43 (60%), Positives = 31/43 (72%)

Query:   255 LSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT 297
             LSTYFS  KLRW LDN     +A EEN  +FGT+D+WLI+ LT
Sbjct:   145 LSTYFSAVKLRWLLDNVKKVQEAVEENRALFGTIDSWLIWSLT 187

 Score = 76 (35.0 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 16/25 (64%), Positives = 20/25 (80%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADIL 599
             PLS L VDGGM+ +  +MQ+QADIL
Sbjct:   418 PLSHLQVDGGMTSNKILMQLQADIL 442

 Score = 72 (33.2 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 12/34 (35%), Positives = 22/34 (64%)

Query:   146 KFPKPGWVECHPQKLLVNVVQCLASSLLSLQTIN 179
             +FP+ GWVE  P+++L +V +C+  +   L  +N
Sbjct:    46 EFPREGWVEQDPKEILQSVYECIEKTCEKLGQLN 79

 Score = 59 (27.2 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 10/28 (35%), Positives = 19/28 (67%)

Query:    47 PLIASIDVGTTSSRCILFNRWGQDVSKH 74
             PL+ ++D GT+S+R ++FN    ++  H
Sbjct:    11 PLVGAVDQGTSSTRFLVFNSKTAELLSH 38

 Score = 44 (20.3 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query:   603 VKVRRSPTAECTALGAAIAANMA 625
             + V +    E TALGAA+AA  A
Sbjct:   444 IPVVKPSMPETTALGAAMAAGAA 466

 Score = 42 (19.3 bits), Expect = 1.3e-44, Sum P(5) = 1.3e-44
 Identities = 7/15 (46%), Positives = 12/15 (80%)

Query:   411 FLLYNTGTKKLISQH 425
             FL++N+ T +L+S H
Sbjct:    25 FLVFNSKTAELLSHH 39

 Score = 41 (18.9 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 8/28 (28%), Positives = 14/28 (50%)

Query:   667 FRSESDDAERRKHWKYWEVAVERSKGWL 694
             F  + +  E    +  W+ AV +S GW+
Sbjct:   487 FEPQINAEESEIRYSTWKKAVMKSIGWV 514

 Score = 35 (16.1 bits), Expect = 3.2e-119, Sum P(9) = 3.2e-119
 Identities = 6/12 (50%), Positives = 9/12 (75%)

Query:   339 MPEIVSSSQYYG 350
             +P + SSS+ YG
Sbjct:   230 LPNVRSSSEIYG 241


gi|516124 glycerol kinase
           Length = 553

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6              |    __        __ _  ___ _     __ |
   Cluster 2503.7                                      |__ __ |

Local hits (HSPs):      ________     ____   ___________________________   
                        __________________________________________________
Database sequence:     |             |             |            |         | 553
                       0           150           300          450

 Score = 313 (144.2 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 59/100 (59%), Positives = 76/100 (76%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEGSVA+AGAV++WLRDNL +I+ S D+  +A  V  S G  FVPAFSGL+APYW+P
Sbjct:   315 YYALEGSVAIAGAVIRWLRDNLGIIETSGDIERLAKEVGTSYGCYFVPAFSGLYAPYWEP 374

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
              AR  + G++QFT   HIA AA+E VCFQ R IL+AM+ D
Sbjct:   375 SARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRD 414

 Score = 195 (89.8 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 35/56 (62%), Positives = 45/56 (80%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAF 433
             +PI GCLGDQ A++VGQ+ ++ G AK TYGTGCFLL NTG K + S+HG LTT+A+
Sbjct:   251 VPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAY 306

 Score = 134 (61.7 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 26/43 (60%), Positives = 30/43 (69%)

Query:   255 LSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT 297
             LSTYFS  KLRW LDN     KA EE   +FGT+D+WLI+ LT
Sbjct:   145 LSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLIWSLT 187

 Score = 86 (39.6 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 16/38 (42%), Positives = 25/38 (65%)

Query:   142 EPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTIN 179
             E T +FPK GWVE  P+++L +V +C+A +   L  +N
Sbjct:    42 ELTQEFPKEGWVEQDPKEILQSVYECIARTCEKLDELN 79

 Score = 73 (33.6 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 15/25 (60%), Positives = 19/25 (76%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADIL 599
             PL  L VDGGM+ +  +MQ+QADIL
Sbjct:   418 PLRHLQVDGGMTNNKVLMQLQADIL 442

 Score = 49 (22.6 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 9/28 (32%), Positives = 17/28 (60%)

Query:    47 PLIASIDVGTTSSRCILFNRWGQDVSKH 74
             PL+ ++  GT S+R ++FN    ++  H
Sbjct:    11 PLVGAVVQGTNSTRFLVFNSKTAELLSH 38

 Score = 44 (20.3 bits), Expect = 8.6e-45, Sum P(5) = 8.6e-45
 Identities = 9/23 (39%), Positives = 14/23 (60%)

Query:   411 FLLYNTGTKKLISQHGALTTLAF 433
             FL++N+ T +L+S H    T  F
Sbjct:    25 FLVFNSKTAELLSHHKVELTQEF 47

 Score = 43 (19.8 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 10/14 (71%), Positives = 11/14 (78%)

Query:   612 ECTALGAAIAANMA 625
             E TALGAA+AA  A
Sbjct:   453 ETTALGAAMAAGAA 466

 Score = 42 (19.3 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 8/28 (28%), Positives = 13/28 (46%)

Query:   667 FRSESDDAERRKHWKYWEVAVERSKGWL 694
             F  +    E    +  W+ AV +S GW+
Sbjct:   487 FEPQIQATESEIRYATWKKAVMKSMGWV 514

 Score = 41 (18.9 bits), Expect = 3.6e-16, Sum P(6) = 3.6e-16
 Identities = 6/18 (33%), Positives = 13/18 (72%)

Query:   466 VQWLRDNLRLIDKSEDVG 483
             ++W+ DN+R + K+ + G
Sbjct:   154 LRWMLDNVRNVQKAVEEG 171

 Score = 37 (17.0 bits), Expect = 4.4e-119, Sum P(9) = 4.4e-119
 Identities = 6/12 (50%), Positives = 9/12 (75%)

Query:   339 MPEIVSSSQYYG 350
             +P + SSS+ YG
Sbjct:   230 LPNVFSSSEIYG 241


sp|P08859|GLPK_ECOLI|gi|121416 GLYCEROL KINASE (ATP:GLYCEROL
            3-PHOSPHOTRANSFERASE) (GLYCEROKINASE) (GK).
            Length = 502


Local hits (HSPs):      __________   ________________________________     
Annotated Domains:      _____  ______________________________________     
                        __________________________________________________
Database sequence:     |              |              |              |     | 502
                       0            150            300            450
__________________

Annotated Domains:
   Entrez               np-binding site: ATP.                    155..167
   Entrez               np-binding site: ATP.                    226..240
   PFAM                 FGGY: FGGY family of carbohydrate kinase 77..444
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 5..28
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 39..49
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 128..147
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 181..217
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 410..425
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 136..148
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 363..383
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 34..40
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 379..387
__________________


 Score = 258 (118.8 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 48/101 (47%), Positives = 72/101 (71%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEG+V +AGA +QWLRD ++LI+ + D    A+ V ++ GV  VPAF+GL APYWDP
Sbjct:   300 NYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDP 359

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSDA 552
              AR  I G+++   A+HI RA +E + +Q R +L+AM +D+
Sbjct:   360 YARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADS 400

 Score = 182 (83.8 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 33/84 (39%), Positives = 56/84 (66%)

Query:   254 LLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQKAFVSDVTNASRTG 313
             ++  YFS +K++W LD+     +     +L+FGTVDTWLI+++T+ +  V+D TNASRT 
Sbjct:   132 VIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTM 191

Query:   314 FMNLSTLKYDNELLEFWGIDKNLI 337
               N+ TL +D+++LE   I + ++
Sbjct:   192 LFNIHTLDWDDKMLEVLDIPREML 215

 Score = 168 (77.4 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 32/55 (58%), Positives = 40/55 (72%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLA 432
             +PI G  GDQ A++ GQL  K G AK TYGTGCF+L NTG K + S++G LTT+A
Sbjct:   238 IPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIA 292

 Score = 90 (41.5 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 15/27 (55%), Positives = 20/27 (74%)

Query:   191 KVICMGIANMRETTILWSRRTGKPIVN 217
             ++  +GI N RETTI+W + TGKPI N
Sbjct:    74 QIAAIGITNQRETTIVWEKETGKPIYN 100

 Score = 66 (30.4 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query:   576 LSVLAVDGGMSRSNEVMQIQADILGPCVK 604
             L  L VDGG   +N +MQ Q+DILG  V+
Sbjct:   404 LHALRVDGGAVANNFLMQFQSDILGTRVE 432

 Score = 57 (26.3 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 12/41 (29%), Positives = 18/41 (43%)

Query:   147 FPKPGWVECHPQKLLVNVVQCLASSLLSLQTINSERVANGL 187
             +PKPGWVE  P ++       L   L      + +  A G+
Sbjct:    40 YPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGI 80

 Score = 52 (24.0 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query:    49 IASIDVGTTSSRCILFNRWGQDVSKHQIEY 78
             I ++D GTTSSR ++ +     +S  Q E+
Sbjct:     7 IVALDQGTTSSRAVVMDHDANIISVSQREF 36

 Score = 47 (21.6 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query:   604 KVRRSPTAECTALGAAIAANMA 625
             +V R    E TALGAA  A +A
Sbjct:   430 RVERPEVREVTALGAAYLAGLA 451

 Score = 37 (17.0 bits), Expect = 1.1e-116, Sum P(9) = 1.1e-116
 Identities = 7/16 (43%), Positives = 10/16 (62%)

Query:   339 MPEIVSSSQYYGDFGI 354
             +PE+  SS+ YG   I
Sbjct:   215 LPEVRRSSEVYGQTNI 230

 Score = 35 (16.1 bits), Expect = 3.3e-100, Sum P(8) = 3.3e-100
 Identities = 6/10 (60%), Positives = 9/10 (90%)

Query:   110 KTSGKPIFSA 119
             K +GKPI++A
Sbjct:    92 KETGKPIYNA 101


pir||S37661|gi|542834 glycerol kinase - human
            Length = 436

 Cluster: 2503.6 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk
 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.6       |      __            _ __   ___  _      _ _ |
   Cluster 2503.7                                       |__  _  |

Local hits (HSPs):       ___  _____________ _______________________       
Annotated Domains:        __    __                 _       ___            
                        __________________________________________________
Database sequence:     |                 |                |               | 436
                       0               150              300
__________________

Annotated Domains:
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 72..84
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 308..328
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 237..245
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 26..33
__________________


 Score = 314 (144.6 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 60/100 (60%), Positives = 75/100 (75%)

Query:   452 HFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDP 511
             ++ALEGSVA+AGAV++WLRDNL +I  SE++  +A  V  S G  FVPAFSGL+APYW+P
Sbjct:   245 YYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEP 304

Query:   512 DARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
              AR  I G++QFT   HIA AA+E VCFQ R IL AM+ D
Sbjct:   305 SARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRD 344

 Score = 195 (89.8 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 36/56 (64%), Positives = 45/56 (80%)

Query:   378 LPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAF 433
             +PI GCLGDQSA++VGQ+ ++ G AK TYGTGCFLL NTG K + S HG LTT+A+
Sbjct:   181 VPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAY 236

 Score = 135 (62.2 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 26/43 (60%), Positives = 30/43 (69%)

Query:   255 LSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT 297
             LSTYFS  KLRW LDN     KA EE   +FGT+D+WLI+ LT
Sbjct:    69 LSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLT 111

 Score = 77 (35.5 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 11/23 (47%), Positives = 19/23 (82%)

Query:   195 MGIANMRETTILWSRRTGKPIVN 217
             +G++N RETT++W + TG+P+ N
Sbjct:    12 IGVSNQRETTVVWDKITGEPLYN 34

 Score = 76 (35.0 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 16/25 (64%), Positives = 20/25 (80%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADIL 599
             PLS L VDGGM+ +  +MQ+QADIL
Sbjct:   348 PLSHLQVDGGMTSNKILMQLQADIL 372

 Score = 51 (23.5 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 11/34 (32%), Positives = 19/34 (55%)

Query:   304 SDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLI 337
             +DVT      F    +L++D +L EF+GI   ++
Sbjct:   121 TDVTMQVGLCFSTCHSLEWDKQLCEFFGIPMEIL 154

 Score = 40 (18.4 bits), Expect = 5.7e-09, Sum P(4) = 5.7e-09
 Identities = 6/14 (42%), Positives = 11/14 (78%)

Query:   466 VQWLRDNLRLIDKS 479
             ++WL DN+R + K+
Sbjct:    78 LRWLLDNVRKVQKA 91

 Score = 35 (16.1 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 6/12 (50%), Positives = 9/12 (75%)

Query:   339 MPEIVSSSQYYG 350
             +P + SSS+ YG
Sbjct:   154 LPNVRSSSEIYG 165

 Score = 34 (15.7 bits), Expect = 8.0e-111, Sum P(8) = 8.0e-111
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query:   246 LRQKTGLPL 254
             ++ KTGLPL
Sbjct:    61 VKSKTGLPL 69


sp|P12011|GNTK_BACSU|gi|121516 GLUCONOKINASE (GLUCONATE KINASE).
            Length = 513

 Cluster: 2599.6 gluconokinase xylulose gluconate kinase xylulokinase
 Cluster: 2599.7 gluconokinase xylb xylulose gluconate gene kinase xylulokinase


Conserved regions:       
   Cluster 2599.6       |____ ____ _____     _____     _______ __|
   Cluster 2599.7       |__    ___|

Local hits (HSPs):      ____            __________ ___  ___________       
Annotated Domains:      ___    _____________________________________   __ 
                        __________________________________________________
Database sequence:     |              |              |             |      | 513
                       0            150            300           450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 74..445
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 4..27
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 94..104
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 124..143
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 171..207
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 411..426
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 131..143
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 363..383
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 379..387
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 493..499
__________________


 Score = 114 (52.5 bits), Expect = 9.8e-23, Sum P(6) = 9.8e-23
 Identities = 21/60 (35%), Positives = 34/60 (56%)

Query:   490 PDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMS 549
             P S G++F P  +G  AP W+PD R +  G++      H+ RAA+EGV +    +  A++
Sbjct:   338 PGSDGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALT 397

 Score = 67 (30.9 bits), Expect = 9.8e-23, Sum P(6) = 9.8e-23
 Identities = 13/27 (48%), Positives = 18/27 (66%)

Query:    52 IDVGTTSSRCILFNRWGQDVSKHQIEY 78
             ID+GTTS++ +LF+  G  V K  I Y
Sbjct:     8 IDIGTTSTKAVLFSENGDVVQKESIGY 34

 Score = 65 (29.9 bits), Expect = 9.8e-23, Sum P(6) = 9.8e-23
 Identities = 15/31 (48%), Positives = 18/31 (58%)

Query:   302 FVSDVTNASRTGFMNLSTLKYDNELLEFWGI 332
             +V D + AS TG MNL  L +D E L   GI
Sbjct:   169 YVIDYSLASATGMMNLKGLDWDEEALRIAGI 199

 Score = 51 (23.5 bits), Expect = 9.8e-23, Sum P(6) = 9.8e-23
 Identities = 9/24 (37%), Positives = 15/24 (62%)

Query:   448 LSKPHFALEGSVAVAGAVVQWLRD 471
             L+  H+ + G V   G V++W+RD
Sbjct:   285 LTDKHWVIGGPVNNGGIVLRWIRD 308

 Score = 46 (21.2 bits), Expect = 9.8e-23, Sum P(6) = 9.8e-23
 Identities = 12/39 (30%), Positives = 19/39 (48%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAEC 613
             P++ +   GG +RS    Q+ +DI    V V  S  + C
Sbjct:   403 PVTRIQATGGFARSEVWRQMMSDIFESEVVVPESYESSC 441

 Score = 37 (17.0 bits), Expect = 9.8e-23, Sum P(6) = 9.8e-23
 Identities = 13/46 (28%), Positives = 18/46 (39%)

Query:   363 HDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGT 408
             H SP+  ++  +    P      D   S +G  A K G    T GT
Sbjct:   216 HCSPEIAIQMGIDPETPFVIGASDGVLSNLGVNAIKKGEIAVTIGT 261

 Score = 37 (17.0 bits), Expect = 5.6e-13, Sum P(5) = 5.6e-13
 Identities = 6/21 (28%), Positives = 15/21 (71%)

Query:    72 SKHQIEYSTSASKGKIGVSGL 92
             +++ I+YS +++ G + + GL
Sbjct:   167 NEYVIDYSLASATGMMNLKGL 187

 Score = 34 (15.7 bits), Expect = 3.2e-13, Sum P(4) = 3.2e-13
 Identities = 8/20 (40%), Positives = 11/20 (55%)

Query:   472 NLRLIDKSEDVGPIASTVPD 491
             NL+ +D  E+   IA   PD
Sbjct:   183 NLKGLDWDEEALRIAGITPD 202


gi|563951 Gluconate kinase
           Length = 513

 Cluster: 2599.6 gluconokinase xylulose gluconate kinase xylulokinase
 Cluster: 2599.7 gluconokinase xylb xylulose gluconate gene kinase xylulokinase


Conserved regions:       
   Cluster 2599.6       |____ ____ _____     _____     _______ __|
   Cluster 2599.7       |__    ___|

Local hits (HSPs):      ____            ____       ___  ___________       
                        __________________________________________________
Database sequence:     |              |              |             |      | 513
                       0            150            300           450

 Score = 104 (47.9 bits), Expect = 2.6e-20, Sum P(5) = 2.6e-20
 Identities = 19/60 (31%), Positives = 33/60 (55%)

Query:   490 PDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMS 549
             P + G++F P  +G  AP W+PD   +  G++      H+ RAA+EGV +    +  A++
Sbjct:   338 PGADGLLFHPYLAGERAPLWNPDVPGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALT 397

 Score = 68 (31.3 bits), Expect = 2.6e-20, Sum P(5) = 2.6e-20
 Identities = 12/28 (42%), Positives = 19/28 (67%)

Query:    52 IDVGTTSSRCILFNRWGQDVSKHQIEYS 79
             ID+GTTS++ +LF+  G  + K  I Y+
Sbjct:     8 IDIGTTSTKAVLFSEKGDVIQKESIGYA 35

 Score = 65 (29.9 bits), Expect = 2.6e-20, Sum P(5) = 2.6e-20
 Identities = 15/31 (48%), Positives = 18/31 (58%)

Query:   302 FVSDVTNASRTGFMNLSTLKYDNELLEFWGI 332
             +V D + AS  G MNL TL +D E L   GI
Sbjct:   169 YVVDYSLASAMGMMNLKTLAWDEEALAIAGI 199

 Score = 52 (24.0 bits), Expect = 2.6e-20, Sum P(5) = 2.6e-20
 Identities = 9/24 (37%), Positives = 16/24 (66%)

Query:   448 LSKPHFALEGSVAVAGAVVQWLRD 471
             L++ H+ + G V   G V++W+RD
Sbjct:   285 LTENHWVIGGPVNNGGIVLRWIRD 308

 Score = 50 (23.0 bits), Expect = 2.6e-20, Sum P(5) = 2.6e-20
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query:   575 PLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAEC 613
             P++ +   GG +RS+   Q+ ADI    V V  S  + C
Sbjct:   403 PVARIQATGGFARSDVWRQMMADIFESEVVVPESYESSC 441


sp|P27155|XYLK_STAXY|gi|139851 XYLULOSE KINASE (XYLULOKINASE).
            Length = 483

 Cluster: 2599.6 gluconokinase xylulose gluconate kinase xylulokinase
 Cluster: 2599.7 gluconokinase xylb xylulose gluconate gene kinase xylulokinase


Conserved regions:       
   Cluster 2599.6       |____  ____ _____      _____     ______ __|
   Cluster 2599.7       |___   ____|

Local hits (HSPs):      ____     _____                    __________      
Annotated Domains:      ___    ______________________________________     
                        __________________________________________________
Database sequence:     |               |              |               |   | 483
                       0             150            300             450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 73..434
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 3..26
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 93..103
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 123..142
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 170..206
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 400..415
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 130..142
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 353..373
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 140..147
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 369..377
__________________


 Score = 77 (35.5 bits), Expect = 1.3e-13, Sum P(4) = 1.3e-13
 Identities = 15/61 (24%), Positives = 30/61 (49%)

Query:   492 SGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSD 551
             + G+++ P   G   P+ D   R + +G+   TT   + RA +EG+ +     +  M ++
Sbjct:   330 ANGLMYTPYLLGERTPHNDASVRGSFIGLDANTTQLDMKRAVIEGITYSINESIHIMKNN 389

Query:   552 A 552
             A
Sbjct:   390 A 390

 Score = 71 (32.7 bits), Expect = 1.3e-13, Sum P(4) = 1.3e-13
 Identities = 16/33 (48%), Positives = 21/33 (63%)

Query:   220 IVWNDTRTIKIVRDKWQNTSVDRQLQLRQKTGL 252
             I+WNDTRT + V D  +N  ++  LQL Q T L
Sbjct:    96 ILWNDTRTSQEVEDIKKNLGLNSLLQLTQNTVL 128

 Score = 62 (28.6 bits), Expect = 1.3e-13, Sum P(4) = 1.3e-13
 Identities = 10/36 (27%), Positives = 22/36 (61%)

Query:    49 IASIDVGTTSSRCILFNRWGQDVSKHQIEYSTSASK 84
             +  ID+GT++ + ++ N+ G  V  + + Y+T+  K
Sbjct:     4 VIGIDIGTSALKTLVVNKSGDVVESYSVSYNTAHPK 39

 Score = 53 (24.4 bits), Expect = 1.3e-13, Sum P(4) = 1.3e-13
 Identities = 10/24 (41%), Positives = 16/24 (66%)

Query:   583 GGMSRSNEVMQIQADILGPCVKVR 606
             GG +++N+ +QIQADI    +  R
Sbjct:   400 GGGAKNNQWLQIQADIFNTTITTR 423


gi|530434 glycerol kinase
           Length = 89

 Cluster: 2503.7 glycerol glucocorticoid-receptor kinase atp:glycerol translocation 3-phosphotransferase promoter glycerokinase protein gk


Conserved regions:       
   Cluster 2503.7          |    _________           ___               |

Local hits (HSPs):         ____________________________________           
                        __________________________________________________
Database sequence:     |          |          |           |          |     | 89
                       0         20         40          60         80

 Score = 138 (63.6 bits), Expect = 3.9e-12, P = 3.9e-12
 Identities = 26/63 (41%), Positives = 37/63 (58%)

Query:   489 VPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAM 548
             V D   V  VP+F+GL +PYWD  +R  I G+ + T   HI RA +E + +QA  ++ AM
Sbjct:     8 VKDDRRVYVVPSFTGLGSPYWDSFSRGAIFGLDRGTRREHIVRATLEAIAYQANDVVDAM 67

Query:   549 SSD 551
               D
Sbjct:    68 GKD 70


sp|P21939|XYLK_LACPE|gi|139850 XYLULOSE KINASE (XYLULOKINASE).
            Length = 501

 Cluster: 2599.6 gluconokinase xylulose gluconate kinase xylulokinase
 Cluster: 2599.7 gluconokinase xylb xylulose gluconate gene kinase xylulokinase


Conserved regions:       
   Cluster 2599.6       |____  ____ __ __     _____     ______ __|
   Cluster 2599.7       |__    ____|

Local hits (HSPs):      _______  ___ __             ____ ______ __        
Annotated Domains:      ___    _____________________________________      
                        __________________________________________________
Database sequence:     |              |              |              |     | 501
                       0            150            300            450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 76..436
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 4..27
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 96..106
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 125..144
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 172..208
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 402..417
   PROSITE              CRYSTALLIN_BETAGAMMA: Crystallins beta a 280..295
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 132..144
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 355..375
__________________


 Score = 76 (35.0 bits), Expect = 8.0e-09, Sum P(6) = 8.0e-09
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query:   492 SGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILK 546
             + G++F P   G  APY D   R + +G+      +   RA +EG+ F    ++K
Sbjct:   332 ANGLLFAPYIVGERAPYADATIRGSFIGVDGSHQRADFVRAVLEGIIFSFEDLIK 386

 Score = 46 (21.2 bits), Expect = 8.0e-09, Sum P(6) = 8.0e-09
 Identities = 8/19 (42%), Positives = 12/19 (63%)

Query:   215 IVNYGIVWNDTRTIKIVRD 233
             ++   I+WNDTRT    R+
Sbjct:    94 VLRPAILWNDTRTTSQCRE 112

 Score = 40 (18.4 bits), Expect = 8.0e-09, Sum P(6) = 8.0e-09
 Identities = 7/14 (50%), Positives = 9/14 (64%)

Query:   259 FSCSKLRWFLDNEP 272
             F+  KL W  +NEP
Sbjct:   133 FTLPKLLWVKENEP 146

 Score = 39 (18.0 bits), Expect = 8.0e-09, Sum P(6) = 8.0e-09
 Identities = 7/32 (21%), Positives = 19/32 (59%)

Query:    48 LIASIDVGTTSSRCILFNRWGQDVSKHQIEYS 79
             ++  ID+GT++ +    ++ G  V++   +Y+
Sbjct:     4 VVLGIDLGTSAVKVSAIDKQGNVVAQASAKYA 35

 Score = 39 (18.0 bits), Expect = 1.1e-05, Sum P(5) = 1.1e-05
 Identities = 9/33 (27%), Positives = 16/33 (48%)

Query:   189 PYKVICMGIANMRETTILWSRRTGKPIVNYGIV 221
             P K   MG+      ++ W ++T  P  ++G V
Sbjct:   289 PGKYYSMGVTLAAGYSLNWFKQTFAPDEDFGTV 321

 Score = 38 (17.5 bits), Expect = 8.0e-09, Sum P(6) = 8.0e-09
 Identities = 9/16 (56%), Positives = 12/16 (75%)

Query:   583 GGMSRSNEVMQIQADI 598
             GG ++S   +QIQADI
Sbjct:   402 GGGAKSALWLQIQADI 417

 Score = 37 (17.0 bits), Expect = 8.0e-09, Sum P(6) = 8.0e-09
 Identities = 8/28 (28%), Positives = 13/28 (46%)

Query:   145 LKFPKPGWVECHPQKLLVNVVQCLASSL 172
             L+ P PG+ E  P+  +    Q +   L
Sbjct:    36 LQQPHPGYSEQDPEDWVTQTTQAIRELL 63

 Score = 34 (15.7 bits), Expect = 0.13, Sum P(5) = 0.12
 Identities = 7/26 (26%), Positives = 13/26 (50%)

Query:   598 ILGPCVKVRRSPTAECTALGAAIAAN 623
             +  P +   R+P A+ T  G+ I  +
Sbjct:   336 LFAPYIVGERAPYADATIRGSFIGVD 361


sp|P29444|XYLK_KLEAE|gi|267426 XYLULOSE KINASE (XYLULOKINASE).
            Length = 483

 Cluster: 2599.6 gluconokinase xylulose gluconate kinase xylulokinase
 Cluster: 2599.7 gluconokinase xylb xylulose gluconate gene kinase xylulokinase


Conserved regions:       
   Cluster 2599.6       |____ _____ __ __     _____     _______ __|
   Cluster 2599.7       |__    ____|

Local hits (HSPs):      ____     ____    ___       ____________    ___    
Annotated Domains:      _____  ______________________________________     
                        __________________________________________________
Database sequence:     |               |              |               |   | 483
                       0             150            300             450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 71..428
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 1..24
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 35..45
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 119..138
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 166..202
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 229..244
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 126..138
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 347..367
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 287..297
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 363..371
__________________


 Score = 74 (34.1 bits), Expect = 1.8e-07, Sum P(5) = 1.8e-07
 Identities = 16/46 (34%), Positives = 26/46 (56%)

Query:   492 SGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGV 537
             +G V F+P  SG   P+ +P A+    G++     + +ARA +EGV
Sbjct:   324 AGPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGV 369

 Score = 54 (24.9 bits), Expect = 1.8e-07, Sum P(5) = 1.8e-07
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query:    52 IDVGTTSSRCILFNRWGQDVSKHQIEYSTS 81
             ID+GT+  + IL N  G+ V+ H  + + S
Sbjct:     5 IDLGTSGVKAILLNEQGEVVASHTEKLTVS 34

 Score = 42 (19.3 bits), Expect = 1.8e-07, Sum P(5) = 1.8e-07
 Identities = 10/19 (52%), Positives = 13/19 (68%)

Query:   615 ALGAAIAANMAFKDVNERP 633
             ALGAA  A++A  D  +RP
Sbjct:   424 ALGAARLAHVAVHDEADRP 442

 Score = 37 (17.0 bits), Expect = 1.8e-07, Sum P(5) = 1.8e-07
 Identities = 13/67 (19%), Positives = 30/67 (44%)

Query:   296 LTKQKAFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIP 355
             L+K ++ V    +A R  +  +S +      L++      L  +P +++++Q   +   P
Sbjct:   267 LSKPESAVHSFCHACRGRWHLMSVMLSAASCLDWAAKLTGLASVPALIAAAQTADESAGP 326

Query:   356 DWIMEKL 362
              W +  L
Sbjct:   327 VWFLPYL 333

 Score = 35 (16.1 bits), Expect = 1.8e-07, Sum P(5) = 1.8e-07
 Identities = 8/30 (26%), Positives = 14/30 (46%)

Query:   215 IVNYGIVWNDTRTIKIVRDKWQNTSVDRQL 244
             ++   I+WND R  +  +      S  RQ+
Sbjct:    89 VLRPAILWNDGRCAEECQLLEDKVSASRQI 118

 Score = 34 (15.7 bits), Expect = 4.5e-07, Sum P(5) = 4.5e-07
 Identities = 6/24 (25%), Positives = 18/24 (75%)

Query:   304 SDVTNASRTGFMNLSTLKYDNELL 327
             SD+++A+ T +++++   + +E+L
Sbjct:   166 SDMSDAAGTMWLDVARRDWSDEML 189


sp|P09099|XYLK_ECOLI|gi|139849 XYLULOSE KINASE (XYLULOKINASE).
            Length = 484

 Cluster: 2599.6 gluconokinase xylulose gluconate kinase xylulokinase
 Cluster: 2599.7 gluconokinase xylb xylulose gluconate gene kinase xylulokinase


Conserved regions:       
   Cluster 2599.6       |____ ________ __     _____     _______ __|
   Cluster 2599.7       |__    ____|

Local hits (HSPs):      ___             ________       ________ ___       
Annotated Domains:      _____  ______________________________________     
                        __________________________________________________
Database sequence:     |               |              |               |   | 484
                       0             150            300             450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 71..429
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 1..24
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 35..45
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 119..138
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 166..202
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 394..409
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 126..138
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 347..367
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 287..297
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 363..371
__________________


 Score = 69 (31.8 bits), Expect = 0.00029, Sum P(5) = 0.00029
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query:   495 VVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGV 537
             V F+P  SG   P+ +P A+    G++     + +ARA +EGV
Sbjct:   327 VWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGV 369

 Score = 44 (20.3 bits), Expect = 0.00029, Sum P(5) = 0.00029
 Identities = 9/21 (42%), Positives = 14/21 (66%)

Query:    52 IDVGTTSSRCILFNRWGQDVS 72
             ID+GT+  + IL N  G+ V+
Sbjct:     5 IDLGTSGVKVILLNEQGEVVA 25

 Score = 36 (16.6 bits), Expect = 44., Sum P(4) = 1.0
 Identities = 9/29 (31%), Positives = 14/29 (48%)

Query:   475 LIDKSEDVGPIASTVPDSGGVVFVPAFSG 503
             L + SE  G +   V  + G+  VP  +G
Sbjct:   202 LYEGSEITGALLPEVAKAWGMATVPVVAG 230

 Score = 35 (16.1 bits), Expect = 0.00029, Sum P(5) = 0.00029
 Identities = 9/18 (50%), Positives = 11/18 (61%)

Query:   583 GGMSRSNEVMQIQADILG 600
             GG +RS    Q+ ADI G
Sbjct:   394 GGGARSEYWRQMLADISG 411

 Score = 35 (16.1 bits), Expect = 0.00029, Sum P(5) = 0.00029
 Identities = 6/27 (22%), Positives = 19/27 (70%)

Query:   302 FVSDVTNASRTGFMNLSTLKYDNELLE 328
             F SD+++A+ T +++++   + + +L+
Sbjct:   164 FASDMSDAAGTMWLDVAKRDWSDVMLQ 190

 Score = 34 (15.7 bits), Expect = 0.00029, Sum P(5) = 0.00029
 Identities = 6/27 (22%), Positives = 15/27 (55%)

Query:   336 LIHMPEIVSSSQYYGDFGIPDWIMEKL 362
             L ++P +++++Q   +   P W +  L
Sbjct:   307 LSNVPALIAAAQQADESAEPVWFLPYL 333


sp|P11553|FUCK_ECOLI|gi|120588 FUCOKINASE.
            Length = 482

 Cluster: 5404.3 fucokinase rhamnulokinase kinase ec rhamnulose 2.7.1.5


Conserved regions:       
   Cluster 5404.3               |__   __ ____    ___|

Local hits (HSPs):       ____             _____  _____       ________     
Annotated Domains:       ___    ______________________________________    
                        __________________________________________________
Database sequence:     |               |               |              |   | 482
                       0             150             300            450
__________________

Annotated Domains:
   PFAM                 FGGY: FGGY family of carbohydrate kinase 87..443
   BLOCKS               BL00933A: FGGY family of carbohydrate ki 15..38
   BLOCKS               BL00933B: FGGY family of carbohydrate ki 107..117
   BLOCKS               BL00933C: FGGY family of carbohydrate ki 137..156
   BLOCKS               BL00933D: FGGY family of carbohydrate ki 184..220
   BLOCKS               BL00933E: FGGY family of carbohydrate ki 409..424
   PROSITE              FGGY_KINASES_1: FGGY family of carbohydr 144..156
   PROSITE              FGGY_KINASES_2: FGGY family of carbohydr 361..381
__________________


 Score = 48 (22.1 bits), Expect = 0.019, Sum P(4) = 0.019
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query:   519 GMSQFTTASHIARAAVEGVCFQARAILKAM 548
             G++  TT  H  RAA+EG+  Q +  L+ +
Sbjct:   365 GVTLNTTRGHFYRAALEGLTAQLQRNLQML 394

 Score = 46 (21.2 bits), Expect = 0.019, Sum P(4) = 0.019
 Identities = 10/26 (38%), Positives = 16/26 (61%)

Query:    48 LIASIDVGTTSSRCILFNRWGQDVSK 73
             +I  +D G T+ R I  NR G+ V++
Sbjct:    15 VILVLDCGATNVRAIAVNRQGKIVAR 40

 Score = 44 (20.3 bits), Expect = 0.019, Sum P(4) = 0.019
 Identities = 8/35 (22%), Positives = 19/35 (54%)

Query:   302 FVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNL 336
             F +D+T A  +  +++    +  ++L+  GI + L
Sbjct:   182 FTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRL 216

 Score = 40 (18.4 bits), Expect = 0.019, Sum P(4) = 0.019
 Identities = 13/29 (44%), Positives = 18/29 (62%)

Query:   577 SVLAVDGGMSRSNEVMQIQADILGPCVKV 605
             S L + GG SR+    QI+A++L   VKV
Sbjct:   403 SELLLVGGGSRNTLWNQIKANMLDIPVKV 431

 Score = 37 (17.0 bits), Expect = 17., Sum P(3) = 1.0
 Identities = 10/35 (28%), Positives = 16/35 (45%)

Query:   639 HDVKKWVFYNGMEKNEQISPEAHPNLKIFRSESDD 673
             HD +  +F  G E+NE +       + + RS   D
Sbjct:   251 HDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVD 285


gi|311895 heat shock protein
           Length = 652

 Cluster: 72.91 t-114 heat kd surface ppf203 shock 78 protein 70 homolog
 Cluster: 72.93 heat shock cognate binding bip kd protein 70 homolog hsp70


Conserved regions:       
   Cluster 72.91                                         | ______  |
   Cluster 72.93                                          |___  |

Local hits (HSPs):                                _____                   
                        __________________________________________________
Database sequence:     |           |          |           |          |    | 652
                       0         150        300         450        600

 Score = 66 (30.4 bits), Expect = 3.3, P = 0.96
 Identities = 18/59 (30%), Positives = 27/59 (45%)

Query:   566 ISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAECTALGAAIAANM 624
             + D  YEKS +  + + GG +R  ++ QI  +        R     E  A GAAI A +
Sbjct:   343 LDDAKYEKSKIDEIVLVGGSTRIPKIQQIIKEFFNGKEPNRGINPDEAVAYGAAIQAGI 401


pir||S24265|gi|103696 intermediate filament protein, cytosolic - common
            lancelet
            Length = 464

 Cluster: 99.75 glial vimentin fibrillary triplet m acidic neurofilament protein nf-l kd
 Cluster: 99.79 glial vimentin fibrillary triplet m neurofilament acidic protein nf-l kd


Conserved regions:       
   Cluster 99.75                                     |       _______|
   Cluster 99.79                                              |  __|

Local hits (HSPs):                  ____ ____             _____    ______ 
                        __________________________________________________
Database sequence:     |                |               |               | | 464
                       0              150             300             450

 Score = 52 (24.0 bits), Expect = 3.4, Sum P(4) = 0.97
 Identities = 9/30 (30%), Positives = 18/30 (60%)

Query:   223 NDTRTIKIVRDKWQNTSVDRQLQLRQKTGL 252
             ND   ++I R+ WQ  + D +++ + + GL
Sbjct:   161 NDKAQLEIERNNWQEQAEDYKMKWQDEAGL 190

 Score = 39 (18.0 bits), Expect = 3.4, Sum P(4) = 0.97
 Identities = 8/28 (28%), Positives = 17/28 (60%)

Query:    14 RYIFRSSQRLYTSLKQEQSRMSKIMEDL 41
             RY+   + +L   +K ++SR +  ++DL
Sbjct:   117 RYLQERNSKLEAQIKIQESREAPNIKDL 144

 Score = 34 (15.7 bits), Expect = 3.4, Sum P(4) = 0.97
 Identities = 10/31 (32%), Positives = 15/31 (48%)

Query:   437 HLQEYGGQKPELSKPHFALEGSVAVAGAVVQ 467
             +L     +   L   + ALEGS+A   A +Q
Sbjct:   324 NLNSLVAENEALKSKNHALEGSLAELEARMQ 354

 Score = 34 (15.7 bits), Expect = 3.4, Sum P(4) = 0.97
 Identities = 13/49 (26%), Positives = 19/49 (38%)

Query:   542 RAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNE 590
             R +L+      FGE  +        S  +Y+ S  S     GG S S +
Sbjct:   403 RKLLEGEEIRLFGESKEGVQQTSSSSSSSYQYSMKSGSGGGGGGSSSGK 451


pir||S35562|gi|479878 sex-determining protein SRY - common gibbon
            Length = 204

 Cluster: 228.38 sex sex-determining determining region protein sry y homolog testis-determining factor
 Cluster: 228.48 sex sex-determining sox region determining sry y protein testis-determining factor


Conserved regions:       
   Cluster 228.38                      |     __         |
   Cluster 228.48                       |    __     |

Local hits (HSPs):                        ______________                  
Annotated Domains:                   ____________________    ___          
                        __________________________________________________
Database sequence:     |            |           |           |           | | 204
                       0           50         100         150         200
__________________

Annotated Domains:
   Entrez               domain: HMG box homology #label HMG      57..132
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 156..164
__________________


 Score = 64 (29.5 bits), Expect = 3.5, Sum P(2) = 0.97
 Identities = 11/31 (35%), Positives = 18/31 (58%)

Query:   635 WKDLHDVKKWVFYNGMEKNEQISPEAHPNLK 665
             WK L + +KW F+   +K + +  E +PN K
Sbjct:    98 WKMLTEAEKWPFFQEAQKLQAMHREKYPNYK 128

 Score = 34 (15.7 bits), Expect = 3.5, Sum P(2) = 0.97
 Identities = 7/24 (29%), Positives = 13/24 (54%)

Query:   226 RTIKIVRDKWQNTSVDRQLQLRQK 249
             R + +   K +N+ + +QL  R K
Sbjct:    76 RKMALENPKMRNSEISKQLGYRWK 99


pir||A48468|gi|477267 Pfgrp=glucose-regulated stress protein homolog -
            Plasmodium falciparum
            Length = 655

 Cluster: 72.91 t-114 heat kd surface ppf203 shock 78 protein 70 homolog
 Cluster: 72.93 heat shock cognate binding bip kd protein 70 homolog hsp70


Conserved regions:       
   Cluster 72.91                                         | ______  |
   Cluster 72.93                                          |_ _  |

Local hits (HSPs):                                ____                    
Annotated Domains:        _             __       ____                     
                        __________________________________________________
Database sequence:     |           |          |           |          |    | 655
                       0         150        300         450        600
__________________

Annotated Domains:
   PROSITE              HSP70_1: Heat shock hsp70 proteins famil 33..40
   PROSITE              HSP70_2: Heat shock hsp70 proteins famil 220..233
   PROSITE              HSP70_3: Heat shock hsp70 proteins famil 357..371
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 341..349
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 342..349
__________________


 Score = 53 (24.4 bits), Expect = 3.7, Sum P(2) = 0.97
 Identities = 10/29 (34%), Positives = 17/29 (58%)

Query:   566 ISDVTYEKSPLSVLAVDGGMSRSNEVMQI 594
             + D  YEKS +  + + GG +R  ++ QI
Sbjct:   344 LDDAKYEKSKIDEIVLVGGSTRIPKIQQI 372

 Score = 50 (23.0 bits), Expect = 3.7, Sum P(2) = 0.97
 Identities = 8/19 (42%), Positives = 14/19 (73%)

Query:   641 VKKWVFYNGMEKNEQISPE 659
             +K++ F+NG E N  I+P+
Sbjct:   373 IKEFEFFNGKEPNRGINPD 391


pir||S10937|gi|105127 35K protein - Human (fragment)
            Length = 120

 Cluster: 228.38 sex sex-determining determining region protein sry y homolog testis-determining factor
 Cluster: 228.48 sex sex-determining sox region determining sry y protein testis-determining factor


Conserved regions:       
   Cluster 228.38              |         ___                 |
   Cluster 228.48                 |      ___         |

Local hits (HSPs):                            _____________               
                        __________________________________________________
Database sequence:     |                    |                    |        | 120
                       0                   50                  100

 Score = 64 (29.5 bits), Expect = 4.0, P = 0.98
 Identities = 11/31 (35%), Positives = 18/31 (58%)

Query:   635 WKDLHDVKKWVFYNGMEKNEQISPEAHPNLK 665
             WK L + +KW F+   +K + +  E +PN K
Sbjct:    54 WKMLTEAEKWPFFQEAQKLQAMHREKYPNYK 84


pir||S35558|gi|479874 sex-determining protein SRY - chimpanzee
            Length = 204

 Cluster: 228.38 sex sex-determining determining region protein sry y homolog testis-determining factor
 Cluster: 228.48 sex sex-determining sox region determining sry y protein testis-determining factor


Conserved regions:       
   Cluster 228.38                      |     __         |
   Cluster 228.48                       |    __     |

Local hits (HSPs):                             _________                  
Annotated Domains:                   ____________________                 
                        __________________________________________________
Database sequence:     |            |           |           |           | | 204
                       0           50         100         150         200
__________________

Annotated Domains:
   Entrez               domain: HMG box homology #label HMG      57..132
__________________


 Score = 64 (29.5 bits), Expect = 5.2, P = 0.99
 Identities = 11/31 (35%), Positives = 18/31 (58%)

Query:   635 WKDLHDVKKWVFYNGMEKNEQISPEAHPNLK 665
             WK L + +KW F+   +K + +  E +PN K
Sbjct:    98 WKMLTEAEKWPFFQEAQKLQAMHREKYPNYK 128


pir||S35560|gi|479876 sex-determining protein SRY - gorilla
            Length = 204

 Cluster: 228.38 sex sex-determining determining region protein sry y homolog testis-determining factor
 Cluster: 228.48 sex sex-determining sox region determining sry y protein testis-determining factor


Conserved regions:       
   Cluster 228.38                      |     __         |
   Cluster 228.48                       |    __     |

Local hits (HSPs):                             _________                  
Annotated Domains:                   ____________________                 
                        __________________________________________________
Database sequence:     |            |           |           |           | | 204
                       0           50         100         150         200
__________________

Annotated Domains:
   Entrez               domain: HMG box homology #label HMG      57..132
__________________


 Score = 64 (29.5 bits)