BEAUTY Search Results

BEAUTY (BLAST Enhanced Alignment Utility) is an enhanced version of the BLAST sequence database search tool. See the BEAUTY Help Page for a more detailed program description, as well as a description of the Protein Family and Conserved Regions databases used in this program. Provided by the Human Genome Sequencing Center, Baylor College of Medicine.

Reference:

Worley KC, Wiese BA, Smith RF. BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results. Genome Res 1995 Sep;5(2):173-84 Abstract


BLASTX 1.4.6MP [16-Oct-94] [Build 16:15:38 Mar 10 1999]

Reference: Gish, Warren and David J. States (1993). Identification of protein coding regions by database similarity search. Nat. Genet. 3:266-72. Altschul, Stephen F., Warren Gish, Webb Miller, Eugene W. Myers, and David J. Lipman (1990). Basic local alignment search tool. J. Mol. Biol. 215:403-10.

Notice: statistical significance is estimated under the assumption that the equivalent of one entire reading frame in the query sequence codes for protein and that significant alignments will involve only coding reading frames.

Query= query (956 letters)

EchoFilter:

  Translating both strands of query sequence in all 6 reading frames
Database: /local/dot5/sl_home/beauty/seqdb/blast-db/CRSeqAnnot.fa 78,469 sequences; 28,902,124 total letters.

WARNING: -hspmax 100 was exceeded with 1 of the database sequences, with as many as 101 HSPs being found at one time.

Histogram:

     Observed Numbers of Database Sequences Satisfying
    Various EXPECTation Thresholds (E parameter values)

        Histogram units:      = 17 Sequences     : less than 17 sequences

 EXPECTation Threshold
 (E parameter)
    |
    V   Observed Counts-->
  10000 3138 1002 |==========================================================
   6310 2136  578 |==================================
   3980 1558  552 |================================
   2510 1006  299 |=================
   1580  707  239 |==============
   1000  468  134 |=======
    631  334  104 |======
    398  230   76 |====
    251  154   46 |==
    158  108   38 |==
    100   70   25 |=
   63.1   45    8 |:
 >>>>>>>>>>>>>>>>>>>>>  Expect = 50.0, Observed = 42  <<<<<<<<<<<<<<<<<
   39.8   37   10 |:
   25.1   27    9 |:
   15.8   18    8 |:
   10.0   10    2 |:
   6.31    8    2 |:
   3.98    6    1 |:
   2.51    5    0 |
   1.58    5    1 |:
   1.00    4    0 |
   0.63    4    0 |
   0.40    4    0 |
   0.25    4    0 |
   0.16    4    0 |
   0.10    4    0 |
  0.063    4    0 |
  0.040    4    0 |
  0.025    4    0 |
  0.016    4    0 |
  0.010    4    0 |
 0.0063    4    0 |
 0.0040    4    0 |
 0.0025    4    1 |:

                                                                      Smallest
                                                                        Sum
                                                      Reading  High  Probability
Sequences producing High-scoring Segment Pairs:         Frame Score  P(N)      N
 
sp|P06978|PGSA  CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PH +1   945  3.6e-126  1
gi|472401       phosphatidylglycerophosphate synthase         +1   400  6.0e-66   3
gi|467087                                                     +1   142  6.0e-18   3
sp|P06197|PIS_  CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTR +1    91  0.0019    1
sp|P37924|FIMD  FIMD PROTEIN PRECURSOR.                       +3    63  0.67      3
sp|P37730|AMYD  POTENTIAL STARCH DEGRADATION PRODUCTS TRANSPO +1    69  0.94      1
gi|525287       aminopeptidase N.                             -2    59  0.997     2
gi|532271       phosphatidylserine synthase                   +1    66  0.998     1
sp|P30343|MER3  MERCURY RESISTANCE OPERON ORF3.               -2    66  0.998     1
gi|461402       methyltransferase                             -3    56  0.99992   2
bbs|140965|gi|  wingless protein=wg/wingless wgIL114 [Drosoph +1    45  0.99996   3
pir||S32661|gi  OAC2 protein - Azorhizobium caulinodans       -2    65  0.99996   1
bbs|114265|gi|  lincomycin-resistance determinant LmrB=23S rR -2    56  0.99999   2
gi|581701       methyltransferase                             -2    56  0.99999   2
sp|P18175|INVO  INVOLUCRIN.                                   -3    57  0.99999   2
gi|581699       bases 361..1197 in X62867                     -2    56  0.99999   2
pir||S33978|gi  hypothetical protein - African clawed frog tr -3    44  0.99999   3
sp|P15586|GL6S  N-ACETYLGLUCOSAMINE-6-SULFATASE PRECURSOR (G6 +2    49  0.999999  3
gi|457707       CshA protein                                  -2    64  1.000000  1
gi|577742       C09G5.6, similar to Collagen                  -1    44  1.000000  4
sp|P20715|HMDH  3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTA +1    58  1.000000  2
sp|P22726|WN5B  WNT-5B PROTEIN PRECURSOR.                     +2    49  1.000000  3
sp|P15822|ZEP1  ZINC FINGER PROTEIN 40 (HUMAN IMMUNODEFICIENC -3    57  1.000000  2
sp|Q05556|CPAB  CYTOCHROME P450 IIA11 (P450-IIA11).           +1    63  1.000000  1
sp|P16766|UL35  HYPOTHETICAL PROTEIN UL35.                    -2    63  1.000000  1
sp|P09615|WNTG  PROTEIN DINT-1 PRECURSOR (WINGLESS PROTEIN).  +3    43  1.000000  3
bbs|140967|gi|  wingless protein=wg/wingless wgIN67 [Drosophi +3    43  1.000000  3
sp|P35503|UD1C  UDP-GLUCURONOSYLTRANSFERASE 1C PRECURSOR, MIC -2    52  1.000000  2
sp|P00744|PRTZ  VITAMIN K-DEPENDENT PROTEIN Z.                -3    45  1.000000  3
sp|P09346|KNOB  KNOB-ASSOCIATED HISTIDINE-RICH PROTEIN PRECUR -3    59  1.000000  2
sp|P13818|KNOB  KNOB-ASSOCIATED HISTIDINE-RICH PROTEIN PRECUR -3    59  1.000000  2
gi|488833       zinc finger protein 51                        -3    50  1.000000  3
prf||1705218D|  Wnt-6 gene                                    +3    47  1.000000  3
gi|347377       MLL-AF4 der(11) fusion protein                -2    46  1.000000  3
gi|443822       H,K-ATPase                                    +1    44  1.000000  3
gi|218415       phosphatidylserine synthase                   +1    61  1.000000  1
gi|530088       aminoalcoholphosphotransferase                +1    61  1.000000  1
gi|580702       fixP                                          +2    54  1.000000  2
sp|P10327|CRYW  130 KD CRYSTAL PROTEIN (DELTA ENDOTOXIN) (CRY -3    61  1.000000  1
gi|490199       lepidoptera larvicidal protein                -3    61  1.000000  1
gi|291529       tegument protein                              -2    61  1.000000  1
sp|P31287|WNT6  XWNT-6 PROTEIN.                               +3    44  1.000000  2

 
Locally-aligned regions (HSPs) with respect to frame 3 of query sequence:

Locus_ID        Clus_ID
sp|P37924|FIMD  634.21 |                                         _________
bbs|140965|gi|         |                              ___                 
sp|P22726|WN5B  76.92  |                               __                 
sp|P09615|WNTG  546.24 |                              ___                 
bbs|140967|gi|         |                              ___                 
prf||1705218D|  76.93  |                            _____                 
gi|443822       217.45 |        ___                                       
sp|P31287|WNT6  76.93  |       ______               _____                 
sp|P31287|WNT6  76.93  |       ______               _____                 
Prosite Hits:                                      _____                  
                        __________________________________________________
Query sequence:        |       |       |       |       |       |       |  | 318
                       0      50     100     150     200     250     300
__________________
Prosite hits:
   LEUCINE_ZIPPER       Leucine zipper pattern.                  179..200
__________________



Locally-aligned regions (HSPs) with respect to frame 2 of query sequence:

Locus_ID        Clus_ID
sp|P37924|FIMD  634.21 |                    ____                          
bbs|140965|gi|         |                         ___                      
sp|P15586|GL6S  4462.4 |           ____    _____                          
sp|P15586|GL6S  4462.4 |           ____    _____                          
sp|P20715|HMDH  339.35 |                                  ____            
sp|P22726|WN5B  76.92  |                        ___                       
sp|P09615|WNTG  546.24 |                         ___                      
bbs|140967|gi|         |                         ___                      
prf||1705218D|  76.93  |                         ___                      
gi|580702       4770   |                        __                ____    
gi|580702       4770   |                        __                ____    
Prosite Hits:                                      _____                  
                        __________________________________________________
Query sequence:        |       |       |       |       |       |       |  | 318
                       0      50     100     150     200     250     300
__________________
Prosite hits:
   LEUCINE_ZIPPER       Leucine zipper pattern.                  179..200
__________________



Locally-aligned regions (HSPs) with respect to frame 1 of query sequence:

Locus_ID        Clus_ID
sp|P06978|PGSA  7579   |    _____________________________                 
gi|472401       7579   |    ___________________ ___ ____                  
gi|472401       7579   |    ___________________ ___ ____                  
gi|472401       7579   |    ___________________ ___ ____                  
gi|467087       7579   |    _____________     _____                       
gi|467087       7579   |    _____________     _____                       
gi|467087       7579   |    _____________     _____                       
sp|P06197|PIS_         |         __________                               
sp|P37924|FIMD  634.21 |           ___                                    
sp|P37730|AMYD  5749.3 |    _____                                         
gi|532271              |         ________                                 
bbs|140965|gi|         |          ____                                    
sp|P15586|GL6S  4462.4 |                          ___                     
sp|P20715|HMDH  339.35 |              ______                              
sp|P22726|WN5B  76.92  |            __                                    
sp|Q05556|CPAB  167.59 |         _________                                
sp|P09615|WNTG  546.24 |          ____                                    
bbs|140967|gi|         |          ____                                    
prf||1705218D|  76.93  |            ___                                   
gi|443822       217.45 |                    ______ _______                
gi|443822       217.45 |                    ______ _______                
gi|218415              |         ________                                 
gi|530088       4944.3 |        ________                                  
Prosite Hits:                                      _____                  
                        __________________________________________________
Query sequence:        |       |       |       |       |       |       |  | 318
                       0      50     100     150     200     250     300
__________________
Prosite hits:
   LEUCINE_ZIPPER       Leucine zipper pattern.                  179..200
__________________



Locally-aligned regions (HSPs) with respect to frame -1 of query sequence:

Locus_ID        Clus_ID
gi|525287       635.21 |      ____                                        
gi|577742              |     _____                                        
sp|P35503|UD1C  1040.14|                       _____                      
sp|P00744|PRTZ  3591.3 |                                   ____           
gi|347377              |                                     _____        
Prosite Hits:                                      _____                  
                        __________________________________________________
Query sequence:        |       |       |       |       |       |       |  | 318
                       0      50     100     150     200     250     300
__________________
Prosite hits:
   LEUCINE_ZIPPER       Leucine zipper pattern.                  179..200
__________________



Locally-aligned regions (HSPs) with respect to frame -2 of query sequence:

Locus_ID        Clus_ID
gi|525287       635.21 |             ________                             
sp|P30343|MER3         |                 _______                          
gi|461402       2586.7 |                      ______                      
pir||S32661|gi  2200.8 |                ______                            
bbs|114265|gi|  2933.6 |                     _______        _____         
bbs|114265|gi|  2933.6 |                     _______        _____         
gi|581701       2933.6 |                     _______        _____         
gi|581701       2933.6 |                     _______        _____         
gi|581699       2933.6 |                     _______        _____         
gi|581699       2933.6 |                     _______        _____         
pir||S33978|gi         |                  _________                       
gi|457707              |                                  ______          
gi|577742              |                   ______           ___           
gi|577742              |                   ______           ___           
sp|P16766|UL35         |              _____________                       
sp|P35503|UD1C  1040.14|                _____                             
sp|P09346|KNOB         |                                   ___            
sp|P13818|KNOB         |                                   ___            
gi|347377              |                        ____                      
gi|291529       7006.2 |                    _______                       
Prosite Hits:                                      _____                  
                        __________________________________________________
Query sequence:        |       |       |       |       |       |       |  | 318
                       0      50     100     150     200     250     300
__________________
Prosite hits:
   LEUCINE_ZIPPER       Leucine zipper pattern.                  179..200
__________________



Locally-aligned regions (HSPs) with respect to frame -3 of query sequence:

Locus_ID        Clus_ID
gi|461402       2586.7 |____                                              
sp|P18175|INVO  5789.3 |                                   ______________ 
sp|P18175|INVO  5789.3 |                                   ______________ 
sp|P18175|INVO  5789.3 |                                   ______________ 
pir||S33978|gi         |                                 ___   ______     
pir||S33978|gi         |                                 ___   ______     
gi|577742              |                                         _____    
sp|P15822|ZEP1  1302.12|                     _____        ______          
sp|P15822|ZEP1  1302.12|                     _____        ______          
sp|P00744|PRTZ  3591.3 |                   ________           ____        
sp|P00744|PRTZ  3591.3 |                   ________           ____        
sp|P09346|KNOB         |                                       _______    
sp|P13818|KNOB         |                                       _______    
gi|488833       28.141 |                     _____           ____ ____    
gi|488833       28.141 |                     _____           ____ ____    
gi|488833       28.141 |                     _____           ____ ____    
gi|347377              |                                        ______    
sp|P10327|CRYW  198.53 |                      ___                         
gi|490199       198.53 |                      ___                         
Prosite Hits:                                      _____                  
                        __________________________________________________
Query sequence:        |       |       |       |       |       |       |  | 318
                       0      50     100     150     200     250     300
__________________
Prosite hits:
   LEUCINE_ZIPPER       Leucine zipper pattern.                  179..200
__________________



Note:In the alignments click on to_old to return to the respective one line description, or (if available) on to_ent to extract the entry from the database.

Use the and icons to retrieve links to Entrez:

E = Retrieve Entrez links (e.g., Medline abstracts, FASTA-formatted sequence reports).
R = Retrieve links to Related sequences (neighbors).
Use the icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
to_oldto_entto_Entrezto_Relatedto_SRSsp|P06978|PGSA_ECOLI|gi|548498 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE
            3-PHOSPHATIDYLTRANSFERASE (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE)
            (PGP SYNTHASE).
            Length = 182

 Cluster: 7579 cdp-diacylglycerol--glycerol-3-phosphate mycobacterium 3-phosphatidyltransferase leprae phosphatidylglycerophosphate synthase pgp


Conserved regions:       
   Cluster 7579         |_____      _________      ___                  |

Local hits (HSPs):      __________________________________________________
Annotated Domains:      _  ______________________________________________ 
                        __________________________________________________
Database sequence:     |             |             |            |         | 182
                       0            50           100          150
__________________

Annotated Domains:
   Entrez               pyrrolidone-carboxylic-acid site         2
   Entrez               Transmembrane region                     14..38
   Entrez               Transmembrane region                     62..82
   Entrez               Transmembrane region                     88..108
   Entrez               Transmembrane region                     147..169
   PFAM                 CDP-OH_P_transf: CDP-alcohol phosphatidy 35..177
   BLOCKS               BL00379: CDP-alcohol phosphatidyltransfe 45..81
   PROSITE              CDP_ALCOHOL_P_TRANSF: CDP-alcohol phosph 49..71
__________________


  Plus Strand HSPs:

 Score = 945 (434.7 bits), Expect = 3.6e-126, P = 3.6e-126
 Identities = 182/182 (100%), Positives = 182/182 (100%), Frame = +1

Query:    82 MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQST 261
             MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQST
Sbjct:     1 MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQST 60

Query:   262 RFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSS 441
             RFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSS
Sbjct:    61 RFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSS 120

Query:   442 VAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMLQYLSAARADLL 621
             VAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMLQYLSAARADLL
Sbjct:   121 VAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMLQYLSAARADLL 180

Query:   622 DQ 627
             DQ
Sbjct:   181 DQ 182


to_oldto_entto_Entrezto_Relatedto_SRSgi|472401 phosphatidylglycerophosphate synthase
           Length = 195

 Cluster: 7579 cdp-diacylglycerol--glycerol-3-phosphate mycobacterium 3-phosphatidyltransferase leprae phosphatidylglycerophosphate synthase pgp


Conserved regions:       
   Cluster 7579         |____     _________      ___                 |

Local hits (HSPs):      ______________________________  _____  ______     
                        __________________________________________________
Database sequence:     |            |            |            |           | 195
                       0           50          100          150

  Plus Strand HSPs:

 Score = 400 (184.0 bits), Expect = 6.0e-66, Sum P(3) = 6.0e-66
 Identities = 72/114 (63%), Positives = 93/114 (81%), Frame = +1

Query:    91 NIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFG 270
             NIP L+T+ RV+LIP F+L+FYLP  WS  AA+ +F  AA TDW DG+LARR  QST FG
Sbjct:     2 NIPNLITVLRVLLIPIFILLFYLPYNWSYMAASSVFAFAAATDWLDGYLARRLEQSTPFG 61

Query:   271 AFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGK 432
             AFLDPVADK++VA+A+VL+ + + + W+TLPAA +I REI++SALREWMAELG+
Sbjct:    62 AFLDPVADKLMVAVALVLLVQEHGNLWLTLPAAVIIGREIVVSALREWMAELGR 115

 Score = 73 (33.6 bits), Expect = 6.0e-66, Sum P(3) = 6.0e-66
 Identities = 15/23 (65%), Positives = 16/23 (69%), Frame = +1

Query:   538 GIALFFVAAVLTLWSMLQYLSAA 606
             G A   +A  LTLWSMLQYL AA
Sbjct:   154 GYAFLLIAGGLTLWSMLQYLRAA 176

 Score = 42 (19.3 bits), Expect = 6.0e-66, Sum P(3) = 6.0e-66
 Identities = 10/16 (62%), Positives = 11/16 (68%), Frame = +1

Query:   469 KTTAQMVALAWLLWRP 516
             KT AQM+AL  LL  P
Sbjct:   129 KTAAQMLALVILLANP 144


to_oldto_entto_Entrezto_Relatedto_SRSgi|467087
          Length = 193

 Cluster: 7579 cdp-diacylglycerol--glycerol-3-phosphate mycobacterium 3-phosphatidyltransferase leprae phosphatidylglycerophosphate synthase pgp


Conserved regions:       
   Cluster 7579           |____      _________     ___                 |

Local hits (HSPs):        ______  _____________        _______            
                        __________________________________________________
Database sequence:     |            |            |            |           | 193
                       0           50          100          150

  Plus Strand HSPs:

 Score = 142 (65.3 bits), Expect = 6.0e-18, Sum P(3) = 6.0e-18
 Identities = 26/47 (55%), Positives = 35/47 (74%), Frame = +1

Query:   181 AAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMV 321
             AA +IF VA +TD  DG LARR+  +T FGAF+DP+ADK L+  A++
Sbjct:    42 AAFVIFTVACITDRLDGLLARRYGMATEFGAFVDPIADKTLIGAALI 88

 Score = 54 (24.8 bits), Expect = 6.0e-18, Sum P(3) = 6.0e-18
 Identities = 11/25 (44%), Positives = 14/25 (56%), Frame = +1

Query:   433 RSSVAVSWIGKVKTTAQMVALAWLL 507
             R  +  SW GK+KT  Q VA+   L
Sbjct:   121 RGVIPASWGGKLKTVVQAVAIGLFL 145

 Score = 45 (20.7 bits), Expect = 6.0e-18, Sum P(3) = 6.0e-18
 Identities = 7/22 (31%), Positives = 15/22 (68%), Frame = +1

Query:    91 NIPTLLTLFRVILIPFFVLVFY 156
             N+  +LT  R++L+P F++  +
Sbjct:     9 NLANILTGLRLMLVPVFLVALF 30


to_oldto_entto_Entrezto_Relatedto_SRSsp|P06197|PIS_YEAST|gi|130240 CDP-DIACYLGLYCEROL--INOSITOL
            3-PHOSPHATIDYLTRANSFERASE (PHOSPHATIDYLINOSITOL SYNTHASE).
            Length = 220


Local hits (HSPs):               ______________                           
Annotated Domains:      _         _____________________________________  _
                        __________________________________________________
Database sequence:     |           |          |          |           |    | 220
                       0          50        100        150         200
__________________

Annotated Domains:
   Entrez               glycosylation site                       4
   Entrez               glycosylation site                       217
   PFAM                 CDP-OH_P_transf: CDP-alcohol phosphatidy 46..205
   BLOCKS               BL00379: CDP-alcohol phosphatidyltransfe 56..92
   PROSITE              ATP_GTP_A: ATP/GTP-binding site motif A  120..127
   PROSITE              CDP_ALCOHOL_P_TRANSF: CDP-alcohol phosph 59..81
__________________


  Plus Strand HSPs:

 Score = 91 (41.9 bits), Expect = 0.0019, P = 0.0019
 Identities = 20/60 (33%), Positives = 30/60 (50%), Frame = +1

Query:   175 PFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWV 354
             P A   ++  + + D  DG +AR++NQ +  GA LD V D+   A  M  +   Y  W V
Sbjct:    42 PTAFTWLYSTSCLLDALDGTMARKYNQVSSLGAVLDMVTDRSSTAGLMCFLCVQYPQWCV 101


to_oldto_entto_Entrezto_Relatedto_SRSsp|P37924|FIMD_SALTY|gi|585135 FIMD PROTEIN PRECURSOR.
            Length = 870

 Cluster: 634.11 cg fimd focd fimbrial protein site s adhesin no precursor
 Cluster: 634.21 cs6 fimd capsule f1 site subunits usher protein synthesis precursor


Conserved regions:       
   Cluster 634.11        |___    __ ________  ______  __ __ _  _________|
   Cluster 634.21                      |_________             _________|

Local hits (HSPs):                  __                 __          ____   
Annotated Domains:        _______________________________________________ 
                        __________________________________________________
Database sequence:     |        |        |       |        |        |      | 870
                       0      150      300     450      600      750
__________________

Annotated Domains:
   PFAM                 Usher: Fimbrial Usher proteins           38..850
   BLOCKS               BL01151: Fimbrial biogenesis outer membr 260..314
   PROSITE              FIMBRIAL_USHER: Fimbrial biogenesis oute 314..324
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 191..198
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 484..491
__________________


  Plus Strand HSPs:

 Score = 63 (29.0 bits), Expect = 1.1, Sum P(3) = 0.67
 Identities = 14/47 (29%), Positives = 24/47 (51%), Frame = +3

Query:   804 STTLPRSGSRVRVSFPAPV*KTSASSGCLAERPEEFGALTKRLCSGL 944
             S+ +P  G+ VR +F   +   +  +  L  RP  FGA+ +   SG+
Sbjct:   764 SSVVPTEGALVRAAFDTRIGVRAIITARLGGRPLPFGAIVRETASGI 810

 Score = 39 (17.9 bits), Expect = 1.1, Sum P(3) = 0.67
 Identities = 6/16 (37%), Positives = 11/16 (68%), Frame = +2

Query:   398 LRYANGWRSWVNAVAW 445
             L YA+GW+    +++W
Sbjct:   554 LGYASGWQGISYSLSW 569

 Score = 36 (16.6 bits), Expect = 1.1, Sum P(3) = 0.67
 Identities = 5/9 (55%), Positives = 8/9 (88%), Frame = +1

Query:   226 DGFLARRWN 252
             DG+ ++RWN
Sbjct:   225 DGYHSQRWN 233


to_oldto_entto_Entrezto_Relatedto_SRSsp|P37730|AMYD_THETU|gi|584757 POTENTIAL STARCH DEGRADATION PRODUCTS TRANSPORT
            SYSTEM PERMEASE PROTEIN AMYD.
            Length = 292

 Cluster: 5749.3 potential sn-glycerol-3-phosphate starch sugar-binding transport products system protein permease ugpa


Conserved regions:       
   Cluster 5749.3                                  | _______   ___   __ |

Local hits (HSPs):        ______                                          
Annotated Domains:        ____       ____ _____   ______________________  
                        __________________________________________________
Database sequence:     |        |       |        |        |       |       | 292
                       0       50     100      150      200     250
__________________

Annotated Domains:
   Entrez               Transmembrane region                     15..35
   Entrez               Transmembrane region                     77..97
   Entrez               Transmembrane region                     110..130
   Entrez               Transmembrane region                     156..176
   Entrez               Transmembrane region                     205..225
   Entrez               Transmembrane region                     260..280
   PFAM                 BPD_transp: Binding-protein-dependent tr 178..255
   BLOCKS               BL00402A: Binding-protein-dependent tran 16..29
   BLOCKS               BL00402B: Binding-protein-dependent tran 188..207
   PROSITE              BPD_TRANSP_INN_MEMBR: Binding-protein-de 179..207
__________________


  Plus Strand HSPs:

 Score = 69 (31.7 bits), Expect = 2.8, P = 0.94
 Identities = 13/29 (44%), Positives = 19/29 (65%), Frame = +1

Query:    88 FNIPTLLTLFRVILIPFFVLVFYLPVTWS 174
             F  PTLL+L  V+LIPF + ++Y    W+
Sbjct:    17 FIAPTLLSLIIVVLIPFIIGIYYSFTDWN 45


to_oldto_entto_Entrezto_Relatedto_SRSgi|525287 aminopeptidase N.
           Length = 963

 Cluster: 635.17 thyrotropin-releasing aminopeptidase microsomal n type ec 3.4.11.2 membrane protein rabbits
 Cluster: 635.21 aminopeptidase yscii lysyl microsomal n a ec lys-ap protein membrane


Conserved regions:       
   Cluster 635.17                |________________ __   _ ___    _  _ __ |
   Cluster 635.21                 |________________        |

Local hits (HSPs):         __                                ___          
                        __________________________________________________
Database sequence:     |       |       |       |       |      |       |   | 963
                       0     150     300     450     600    750     900

  Minus Strand HSPs:

 Score = 59 (27.1 bits), Expect = 5.8, Sum P(2) = 1.0
 Identities = 12/47 (25%), Positives = 26/47 (55%), Frame = -2

Query:   700 YLAR*VNDIFHHF*SFAENYAETITDQANLHAQRSNIATLTTESVPQ 560
             YL + V  +F HF +  +N+ E   +  + +++ + I+T  +  +PQ
Sbjct:   718 YLRKQVEPLFQHFETLTKNWTERPENLMDQYSEINAISTACSNGLPQ 764

 Score = 44 (20.2 bits), Expect = 5.8, Sum P(2) = 1.0
 Identities = 8/16 (50%), Positives = 9/16 (56%), Frame = -1

Query:   824 RPWQGRALPTELFPHS 777
             +PW    LPT L P S
Sbjct:    65 KPWNRYRLPTTLLPDS 80


to_oldto_entto_Entrezto_Relatedto_SRSgi|532271 phosphatidylserine synthase
           Length = 177


Local hits (HSPs):              _____________                             
                        __________________________________________________
Database sequence:     |             |             |              |       | 177
                       0            50           100            150

  Plus Strand HSPs:

 Score = 66 (30.4 bits), Expect = 6.3, P = 1.0
 Identities = 16/45 (35%), Positives = 21/45 (46%), Frame = +1

Query:   181 AAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIA 315
             +A L        D+FDG  AR+ N  +  G  LD  AD V   +A
Sbjct:    30 SAVLFIFTGMFLDFFDGMAARKLNAVSDMGRELDSFADLVTFGVA 74


to_oldto_entto_Entrezto_Relatedto_SRSsp|P30343|MER3_STRLI|gi|266525 MERCURY RESISTANCE OPERON ORF3.
            Length = 189


Local hits (HSPs):                                           ____________ 
Annotated Domains:            ___          ____                           
                        __________________________________________________
Database sequence:     |            |             |            |          | 189
                       0           50           100          150
__________________

Annotated Domains:
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 24..34
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 75..85
__________________


  Minus Strand HSPs:

 Score = 66 (30.4 bits), Expect = 6.5, P = 1.0
 Identities = 16/43 (37%), Positives = 21/43 (48%), Frame = -2

Query:   625 DQANLHAQRSNIATLTTESVPQPQRKVQYRRTQPKCSDATAAM 497
             D+    +QR  +A L+T  V  PQ KV YR T P       A+
Sbjct:   142 DKGAALSQRYQVAALSTLIVVAPQGKVTYRATDPSADQIQDAL 184


to_oldto_entto_Entrezto_Relatedto_SRSgi|461402 methyltransferase
           Length = 492

 Cluster: 2586.5 chemotaxis cher hypothetical methyltransferase protein 19
 Cluster: 2586.7 cher hypothetical similar protein to product methyltransferase gene: number x73681


Conserved regions:       
   Cluster 2586.5        |   __  _____    ______|
   Cluster 2586.7             |  _______    ____|

Local hits (HSPs):                                       ___        ____  
                        __________________________________________________
Database sequence:     |               |              |              |    | 492
                       0             150            300            450

  Minus Strand HSPs:

 Score = 56 (25.8 bits), Expect = 9.5, Sum P(2) = 1.0
 Identities = 10/25 (40%), Positives = 16/25 (64%), Frame = -3

Query:   951 GFAIRYITALLTRQILQAFQPDIRL 877
             G  +RY+   +TR +L   QP++RL
Sbjct:   329 GRFLRYVAGEITRNLLTLIQPELRL 353

 Score = 43 (19.8 bits), Expect = 9.5, Sum P(2) = 1.0
 Identities = 10/29 (34%), Positives = 12/29 (41%), Frame = -2

Query:   520 CSDATAAMPTPPSGQWFSLSQSRRRPRYC 434
             CS       TP S +      SRRR + C
Sbjct:   436 CSGPNCTCRTPSSNRKSPARSSRRRTKKC 464


to_oldto_entto_Entrezto_Relatedto_SRSbbs|140965|gi|455942 wingless protein=wg/wingless wgIL114 [Drosophila, Peptide
            Mutant, 468 aa]
            Length = 468


Local hits (HSPs):               ___      ___                         __  
                        __________________________________________________
Database sequence:     |               |               |               |  | 468
                       0             150             300             450

  Plus Strand HSPs:

 Score = 45 (20.7 bits), Expect = 10., Sum P(3) = 1.0
 Identities = 9/19 (47%), Positives = 12/19 (63%), Frame = +1

Query:   208 AVTDWFDGFLARRWNQSTR 264
             A+++    F  RRWN STR
Sbjct:    89 AISECQHQFRNRRWNSSTR 107

 Score = 43 (19.8 bits), Expect = 10., Sum P(3) = 1.0
 Identities = 7/11 (63%), Positives = 8/11 (72%), Frame = +3

Query:   585 VAIFERCACRF 617
             V + ERCAC F
Sbjct:   437 VVVVERCACTF 447

 Score = 38 (17.5 bits), Expect = 10., Sum P(3) = 1.0
 Identities = 7/15 (46%), Positives = 7/15 (46%), Frame = +2

Query:   482 RWWRWHGCCGVRTFG 526
             R W W GC     FG
Sbjct:   178 RDWEWGGCSDNIGFG 192


to_oldto_entto_Entrezto_Relatedto_SRSpir||S32661|gi|420769 OAC2 protein - Azorhizobium caulinodans
            Length = 296

 Cluster: 2200.8 dtdp-4-dehydrorhamnose putative thymidine protein dtdp-4-keto-l-rhamnose reductase dtdp-6-deoxy-l-mannose dehydrogenase dtdp-l-rhamnose synthetase


Conserved regions:       
   Cluster 2200.8       |___    _______________     _____   |

Local hits (HSPs):                                           ______       
                        __________________________________________________
Database sequence:     |        |       |        |       |        |       | 296
                       0       50     100      150     200      250

  Minus Strand HSPs:

 Score = 65 (29.9 bits), Expect = 10., P = 1.0
 Identities = 12/32 (37%), Positives = 19/32 (59%), Frame = -2

Query:   643 YAETITDQANLHAQRSNIATLTTESVPQPQRK 548
             +A+ I D+A  +  RS +A +TT   P P R+
Sbjct:   223 FAQAIIDRAATYTGRSEVAAITTAEYPTPARR 254


to_oldto_entto_Entrezto_Relatedto_SRSbbs|114265|gi|256412 lincomycin-resistance determinant LmrB=23S rRNA
            adenine(2058)-N-methyltransferase homolog [Streptomyces
            lincolnensis, 78-11, Peptide, 278 aa]
            Length = 278

 Cluster: 2933.6 midecamycin-resistance myrb resistance erythromycin rrna n-6-methyltransferase protein x62867 streptomyces peptide


Conserved regions:       
   Cluster 2933.6        |_    _____    ____ _____  ____   |

Local hits (HSPs):                            ________               _____
                        __________________________________________________
Database sequence:     |        |        |        |        |        |     | 278
                       0       50      100      150      200      250

  Minus Strand HSPs:

 Score = 56 (25.8 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 12/43 (27%), Positives = 19/43 (44%), Frame = -2

Query:   547 VQYRRTQPKCSDATAAMPTPPSGQWFSLSQSRRRPRYCVYPTP 419
             VQ+   + +      ++ T  S  WF  S  +R PR+   P P
Sbjct:   125 VQWEVARRRAGIGGCSLVTAESWPWFDFSVLKRVPRFAFRPAP 167

 Score = 40 (18.4 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 9/26 (34%), Positives = 11/26 (42%), Frame = -2

Query:   253 GSSGVPENHRTSQSPPRRRK*ARRQT 176
             G   VP   R    PPR  +  RR +
Sbjct:   252 GGRSVPRTRRPRGLPPRTSRGPRRNS 277


to_oldto_entto_Entrezto_Relatedto_SRSgi|581701 methyltransferase
           Length = 278

 Cluster: 2933.6 midecamycin-resistance myrb resistance erythromycin rrna n-6-methyltransferase protein x62867 streptomyces peptide


Conserved regions:       
   Cluster 2933.6        |_    _____    ____ _____  ____   |

Local hits (HSPs):                            ________               _____
                        __________________________________________________
Database sequence:     |        |        |        |        |        |     | 278
                       0       50      100      150      200      250

  Minus Strand HSPs:

 Score = 56 (25.8 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 12/43 (27%), Positives = 19/43 (44%), Frame = -2

Query:   547 VQYRRTQPKCSDATAAMPTPPSGQWFSLSQSRRRPRYCVYPTP 419
             VQ+   + +      ++ T  S  WF  S  +R PR+   P P
Sbjct:   125 VQWEVARRRAGIGGCSLVTAESWPWFDFSVLKRVPRFAFRPAP 167

 Score = 40 (18.4 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 9/26 (34%), Positives = 11/26 (42%), Frame = -2

Query:   253 GSSGVPENHRTSQSPPRRRK*ARRQT 176
             G   VP   R    PPR  +  RR +
Sbjct:   252 GGRSVPRTRRPRGLPPRTSRGPRRNS 277


to_oldto_entto_Entrezto_Relatedto_SRSsp|P18175|INVO_PIG|gi|124735 INVOLUCRIN.
            Length = 347

 Cluster: 5789.3 involucrin


Conserved regions:       
   Cluster 5789.3       |_____________________                |

Local hits (HSPs):      ______       __________                           
Annotated Domains:      ____________                      _______         
                        __________________________________________________
Database sequence:     |                     |                     |      | 347
                       0                   150                   300
__________________

Annotated Domains:
   BLOCKS               BL00795A: Involucrin proteins.           1..35
   BLOCKS               BL00795B: Involucrin proteins.           41..80
   BLOCKS               BL00795C: Involucrin proteins.           240..284
   PROSITE              INVOLUCRIN: Involucrin signature.        1..11
__________________


  Minus Strand HSPs:

 Score = 57 (26.2 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 13/37 (35%), Positives = 21/37 (56%), Frame = -3

Query:   279 KESTKPGTLVPAACQKTIEPVSHRRDAENERGGKRRP 169
             ++ T P TL PA  Q+ ++PVS   D + E+  +  P
Sbjct:     3 QQYTLPVTLPPALSQEPLKPVSPPADTQQEQVKQATP 39

 Score = 40 (18.4 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 11/47 (23%), Positives = 24/47 (51%), Frame = -3

Query:   162 RQIKDQYKEWDKDDTEQCKQRRDIKLHNDG*LSVVSKITPMLLQRHQ 22
             +Q + Q +E   D  +Q ++ ++ +LH D      S++  + +  HQ
Sbjct:   110 QQQESQEQELHVDQQQQQQESQEQELHVDQQQQQESQVQELHVGHHQ 156

 Score = 36 (16.6 bits), Expect = 38., Sum P(2) = 1.0
 Identities = 8/29 (27%), Positives = 17/29 (58%), Frame = -3

Query:   162 RQIKDQYKEWDKDDTEQCKQRRDIKLHND 76
             +Q + Q +E   D  +Q ++ ++ +LH D
Sbjct:    94 QQQESQVQELHVDQQQQQQESQEQELHVD 122


to_oldto_entto_Entrezto_Relatedto_SRSgi|581699 bases 361..1197 in X62867
           Length = 279

 Cluster: 2933.6 midecamycin-resistance myrb resistance erythromycin rrna n-6-methyltransferase protein x62867 streptomyces peptide


Conserved regions:       
   Cluster 2933.6        |_    _____     ___ _____  ____   |

Local hits (HSPs):                            ________               _____
                        __________________________________________________
Database sequence:     |        |        |        |        |        |     | 279
                       0       50      100      150      200      250

  Minus Strand HSPs:

 Score = 56 (25.8 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 12/43 (27%), Positives = 19/43 (44%), Frame = -2

Query:   547 VQYRRTQPKCSDATAAMPTPPSGQWFSLSQSRRRPRYCVYPTP 419
             VQ+   + +      ++ T  S  WF  S  +R PR+   P P
Sbjct:   126 VQWEVARRRAGIGGCSLVTAESWPWFDFSVLKRVPRFAFRPAP 168

 Score = 40 (18.4 bits), Expect = 11., Sum P(2) = 1.0
 Identities = 9/26 (34%), Positives = 11/26 (42%), Frame = -2

Query:   253 GSSGVPENHRTSQSPPRRRK*ARRQT 176
             G   VP   R    PPR  +  RR +
Sbjct:   253 GGRSVPRTRRPRGLPPRTSRGPRRNS 278


to_oldto_entto_Entrezto_Relatedto_SRSpir||S33978|gi|479473 hypothetical protein - African clawed frog transposon
            1a11
            Length = 653


Local hits (HSPs):                 ______                          ___    
Annotated Domains:                           __                           
                        __________________________________________________
Database sequence:     |           |          |           |          |    | 653
                       0         150        300         450        600
__________________

Annotated Domains:
   PROSITE              ATP_GTP_A: ATP/GTP-binding site motif A  284..291
__________________


  Minus Strand HSPs:

 Score = 44 (20.2 bits), Expect = 11., Sum P(3) = 1.0
 Identities = 7/13 (53%), Positives = 9/13 (69%), Frame = -3

Query:   318 HGDSHENFICHRV 280
             HGD+   F CH+V
Sbjct:   206 HGDTRRCFSCHQV 218

 Score = 43 (19.8 bits), Expect = 11., Sum P(3) = 1.0
 Identities = 10/27 (37%), Positives = 15/27 (55%), Frame = -3

Query:   192 ERGGKRRPGDRQIKDQYKEWDKDDTEQ 112
             ERG + RP D   K Q  E +++  E+
Sbjct:   572 ERGTRDRPEDPTGKGQIAETEENQEEE 598

 Score = 41 (18.9 bits), Expect = 11., Sum P(3) = 1.0
 Identities = 13/48 (27%), Positives = 19/48 (39%), Frame = -2

Query:   598 SNIATLTTESVPQPQRKVQYRRTQPKCSDATAAMPTPPSGQWFSLSQS 455
             + IA     S     RK  +   +P+ +D    MP   S Q    S+S
Sbjct:   147 AEIADTYAASRVPDSRKSSFHSWKPRKADVNLTMPPSLSAQHARSSES 194


to_oldto_entto_Entrezto_Relatedto_SRSsp|P15586|GL6S_HUMAN|gi|232126 N-ACETYLGLUCOSAMINE-6-SULFATASE PRECURSOR (G6S)
            (GLUCOSAMINE-6-SULFATASE).
            Length = 552

 Cluster: 4462.4 mature n-acetylglucosamine-6-sulfatase arylsulfatase precursor kd protein in ilvo-ibpb intergenic region


Conserved regions:       
   Cluster 4462.4           |____            _____________|

Local hits (HSPs):         __              ___              __            
Annotated Domains:        _ _________________________________________     
                        __________________________________________________
Database sequence:     |             |             |            |         | 552
                       0           150           300          450
__________________

Annotated Domains:
   Entrez               modified site: 2-AMINO-3-OXOPROPIONIC AC 91
   Entrez               glycosylation site                       111
   Entrez               glycosylation site                       117
   Entrez               glycosylation site                       183
   Entrez               glycosylation site                       198
   Entrez               glycosylation site                       210
   Entrez               glycosylation site                       279
   Entrez               glycosylation site                       317
   Entrez               glycosylation site                       362
   Entrez               glycosylation site                       387
   Entrez               glycosylation site                       405
   Entrez               glycosylation site                       422
   Entrez               glycosylation site                       449
   Entrez               glycosylation site                       480
   PFAM                 Sulfatase: Sulfatase                     47..485
   BLOCKS               BL00523A: Sulfatases proteins.           47..63
   BLOCKS               BL00523B: Sulfatases proteins.           91..102
   BLOCKS               BL00523C: Sulfatases proteins.           141..151
   BLOCKS               BL00523D: Sulfatases proteins.           224..235
   BLOCKS               BL00523E: Sulfatases proteins.           299..328
   BLOCKS               BL00523F: Sulfatases proteins.           373..383
   BLOCKS               BL00523G: Sulfatases proteins.           478..487
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 24..34
   PROSITE              SULFATASE_1: Sulfatases signature 1.     89..101
   PROSITE              SULFATASE_2: Sulfatases signature 2.     141..151
__________________


  Plus Strand HSPs:

 Score = 49 (22.5 bits), Expect = 14., Sum P(3) = 1.0
 Identities = 12/18 (66%), Positives = 13/18 (72%), Frame = +2

Query:   230 VFWHAAGTRVPGLVLSLT 283
             VF  AAGTR P +VL LT
Sbjct:    37 VFGVAAGTRRPNVVLLLT 54

 Score = 41 (18.9 bits), Expect = 14., Sum P(3) = 1.0
 Identities = 7/13 (53%), Positives = 9/13 (69%), Frame = +1

Query:   502 LLWRPNIWVEYAG 540
             L WR ++ VEY G
Sbjct:   406 LTWRSDVLVEYQG 418

 Score = 36 (16.6 bits), Expect = 14., Sum P(3) = 1.0
 Identities = 8/24 (33%), Positives = 13/24 (54%), Frame = +2

Query:   383 VKLLFLRYANGWRSWVNAVAWPSP 454
             V L FL Y + +  +   +A P+P
Sbjct:   211 VSLDFLDYKSNFEPFFMMIATPAP 234


to_oldto_entto_Entrezto_Relatedto_SRSgi|457707 CshA protein
           Length = 2508


Local hits (HSPs):                   _                                    
                        __________________________________________________
Database sequence:     |         |         |         |         |         || 2508
                       0       500      1000      1500      2000      2500

  Minus Strand HSPs:

 Score = 64 (29.4 bits), Expect = 17., P = 1.0
 Identities = 12/34 (35%), Positives = 19/34 (55%), Frame = -2

Query:   304 RELYLPQGQGKHQTGYSGSSGVPENHRTSQSPPR 203
             R +Y PQG+ +  TG+ G +     H T++ P R
Sbjct:   668 RRVYPPQGEKQESTGFQGETQNASVHFTAKGPDR 701


to_oldto_entto_Entrezto_Relatedto_SRSgi|577742 C09G5.6, similar to Collagen
           Length = 963


Local hits (HSPs):               __     __      __                 __     
                        __________________________________________________
Database sequence:     |       |       |       |       |      |       |   | 963
                       0     150     300     450     600    750     900

  Minus Strand HSPs:

 Score = 44 (20.2 bits), Expect = 17., Sum P(4) = 1.0
 Identities = 10/26 (38%), Positives = 14/26 (53%), Frame = -1

Query:   845 RDSNSRPRPWQGRALPTELFPHSSSN 768
             R+  S  RP+  +  P+   PHSS N
Sbjct:   180 REPASSRRPYPPQQPPSTSAPHSSPN 205

 Score = 38 (17.5 bits), Expect = 17., Sum P(4) = 1.0
 Identities = 8/20 (40%), Positives = 10/20 (50%), Frame = -2

Query:   268 QTGYSGSSGVPENHRTSQSP 209
             Q G  G+ G P  H  + SP
Sbjct:   469 QDGQPGAPGAPGYHGMNGSP 488

 Score = 37 (17.0 bits), Expect = 17., Sum P(4) = 1.0
 Identities = 10/30 (33%), Positives = 11/30 (36%), Frame = -2

Query:   577 TESVPQPQRKVQYRRTQPKCSDATAAMPTP 488
             T + P P    Q  R  P  SD      TP
Sbjct:   316 TRNPPNPTNTRQPSRPVPPTSDGHIEATTP 345

 Score = 36 (16.6 bits), Expect = 17., Sum P(4) = 1.0
 Identities = 10/29 (34%), Positives = 16/29 (55%), Frame = -3

Query:   168 GDRQIKDQYKEWDKDDTEQCKQRRDIKLH 82
             GD++ K+Q +  D    E+ K+R   K H
Sbjct:   838 GDKRKKNQPEYEDISKPEEDKERAMEKHH 866


to_oldto_entto_Entrezto_Relatedto_SRSsp|P20715|HMDH_XENLA|gi|123347 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE
            (HMG-COA REDUCTASE).
            Length = 883

 Cluster: 339.32 3-hydroxy-3-methylglutaryl 3-hydroxy-3-methylglutaryl-coenzyme human hydroxymethylglutaryl-coa coenzyme 1 2 a reductase hmg-coa
 Cluster: 339.34 3-hydroxy-3-methylglutaryl-coenzyme human hydroxymethylglutaryl-coa 1 2 a nadph reductase ec hmg-coa
 Cluster: 339.35 3-hydroxy-3-methylglutaryl-coenzyme hydroxymethylglutaryl-coa nadph a reductase 2 hmg-coa hmgr 1.1.1.34 ec


Conserved regions:       
   Cluster 339.32                                 |  _____  ____ _______|
   Cluster 339.34                                     |__   __________ _|
   Cluster 339.35                                             |_ __|

Local hits (HSPs):                    __                  __              
Annotated Domains:      __________________________________________________
                        __________________________________________________
Database sequence:     |        |       |        |       |        |       | 883
                       0      150     300      450     600      750
__________________

Annotated Domains:
   Entrez               Domain: MEMBRANE-BOUND.                  1..341
   Entrez               Domain: LINKER.                          342..444
   Entrez               Domain: CATALYTIC.                       445..883
   Entrez               Transmembrane region                     10..39
   Entrez               Transmembrane region                     57..78
   Entrez               Transmembrane region                     90..114
   Entrez               Transmembrane region                     124..149
   Entrez               Transmembrane region                     160..187
   Entrez               Transmembrane region                     192..220
   Entrez               Transmembrane region                     315..339
   Entrez               active site                              554
   Entrez               active site                              762
   Entrez               active site: GENERAL BASE.               861
   PFAM                 HMG-CoA_red1: Hydroxymethylglutaryl-coen 634..666
   PFAM                 HMG-CoA_red2: Hydroxymethylglutaryl-coen 776..804
   PRINTS               HMGCOARDTASE1: HMG-CoA reductase motif I 521..542
   PRINTS               HMGCOARDTASE2: HMG-CoA reductase motif I 548..568
   PRINTS               HMGCOARDTASE3: HMG-CoA reductase motif I 639..657
   PRINTS               HMGCOARDTASE4: HMG-CoA reductase motif I 679..704
   PRINTS               HMGCOARDTASE5: HMG-CoA reductase motif V 730..756
   PRINTS               HMGCOARDTASE6: HMG-CoA reductase motif V 785..806
   BLOCKS               BL00066A: Hydroxymethylglutaryl-coenzyme 88..97
   BLOCKS               BL00066B: Hydroxymethylglutaryl-coenzyme 534..586
   BLOCKS               BL00066C: Hydroxymethylglutaryl-coenzyme 623..660
   BLOCKS               BL00066D: Hydroxymethylglutaryl-coenzyme 670..718
   BLOCKS               BL00066E: Hydroxymethylglutaryl-coenzyme 730..777
   BLOCKS               BL00066F: Hydroxymethylglutaryl-coenzyme 826..867
   PROSITE              HMG_COA_REDUCTASE_1: Hydroxymethylglutar 641..655
   PROSITE              HMG_COA_REDUCTASE_2: Hydroxymethylglutar 797..804
   PROSITE              HMG_COA_REDUCTASE_3: Hydroxymethylglutar 851..864
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 511..521
__________________


  Plus Strand HSPs:

 Score = 58 (26.7 bits), Expect = 18., Sum P(2) = 1.0
 Identities = 10/30 (33%), Positives = 20/30 (66%), Frame = +1

Query:   280 DPVADKVLVAIAMVLVTEHYHSWWVTLPAA 369
             +PV  +V + +++ LV  H HS W++ P++
Sbjct:   251 NPVTQRVKMIMSLGLVLVHAHSRWISEPSS 280

 Score = 41 (18.9 bits), Expect = 18., Sum P(2) = 1.0
 Identities = 7/20 (35%), Positives = 15/20 (75%), Frame = +2

Query:   662 KVVKNIVDSSRQVSRMQRIE 721
             KV+K+  DS+ + +R+ R++
Sbjct:   611 KVIKDAFDSTSRFARLGRLQ 630


to_oldto_entto_Entrezto_Relatedto_SRSsp|P22726|WN5B_MOUSE|gi|139724 WNT-5B PROTEIN PRECURSOR.
            Length = 372

 Cluster: 76.79 wnt-5b xwnt-5c wnt-5a protein xwnt-5a precursor xenopus zebrafish peptide aa
 Cluster: 76.92 wnt-3a wnt-5b wnt-5a gene protein product precursor peptide partial aa


Conserved regions:       
   Cluster 76.79                                       |__     __  __|
   Cluster 76.92                                               |   _|

Local hits (HSPs):                   __      ___                      __  
Annotated Domains:             ___________________________________________
                        __________________________________________________
Database sequence:     |                    |                   |         | 372
                       0                  150                 300
__________________

Annotated Domains:
   Entrez               glycosylation site                       106
   Entrez               glycosylation site                       112
   Entrez               glycosylation site                       304
   Entrez               glycosylation site                       318
   PFAM                 wnt: wnt family of developmental signali 60..372
   BLOCKS               BL00246A: Wnt-1 family proteins.         88..107
   BLOCKS               BL00246B: Wnt-1 family proteins.         123..157
   BLOCKS               BL00246C: Wnt-1 family proteins.         169..193
   BLOCKS               BL00246D: Wnt-1 family proteins.         210..262
   BLOCKS               BL00246E: Wnt-1 family proteins.         326..371
   PROSITE              WNT1: Wnt-1 family signature.            230..239
__________________


  Plus Strand HSPs:

 Score = 49 (22.5 bits), Expect = 19., Sum P(3) = 1.0
 Identities = 8/12 (66%), Positives = 8/12 (66%), Frame = +2

Query:   470 KPLPRWWRWHGC 505
             K LPR W W GC
Sbjct:   163 KDLPRDWLWGGC 174

 Score = 37 (17.0 bits), Expect = 19., Sum P(3) = 1.0
 Identities = 6/7 (85%), Positives = 6/7 (85%), Frame = +3

Query:   597 ERCACRF 617
             ERC CRF
Sbjct:   345 ERCHCRF 351

 Score = 36 (16.6 bits), Expect = 19., Sum P(3) = 1.0
 Identities = 7/10 (70%), Positives = 7/10 (70%), Frame = +1

Query:   232 FLARRWNQST 261
             F  RRWN ST
Sbjct:   100 FRQRRWNCST 109


to_oldto_entto_Entrezto_Relatedto_SRSsp|P15822|ZEP1_HUMAN|gi|141697 ZINC FINGER PROTEIN 40 (HUMAN IMMUNODEFICIENCY
            VIRUS TYPE I ENHANCER-BINDING PROTEIN 1) (HIV-EP1) (MAJOR
            HISTOCOMPATIBILITY COMPLEX BINDING PROTEIN 1) (MBP-1) (POSITIVE
            REGULATORY DOMAIN II BINDING FACTOR 1) (PRDII-BF1).
            Length = 2717

 Cluster: 1302.9 zinc finger virus major protein type histocompatibility enhancer-binding binding 1
 Cluster: 1302.12 dna-binding zinc finger major protein histocompatibility enhancer-binding binding 1 2


Conserved regions:       
   Cluster 1302.9                                            |___  |
   Cluster 1302.12                                            |_|

Local hits (HSPs):        __         _                                    
Annotated Domains:             __     _  __                   __          
                        __________________________________________________
Database sequence:     |         |        |        |        |        |    | 2717
                       0       500     1000     1500     2000     2500
__________________

Annotated Domains:
   Entrez               Domain: ZINC-FINGERS.                    406..456
   Entrez               Zinc finger region: C2H2-TYPE.           406..428
   Entrez               Zinc finger region: C2H2-TYPE.           434..456
   Entrez               Domain: POLY-SER.                        803..806
   Entrez               Zinc finger region: C2HC-TYPE.           958..981
   Entrez               Domain: ZINC-FINGERS.                    2087..2139
   Entrez               Zinc finger region: C2H2-TYPE.           2087..2109
   Entrez               Zinc finger region: C2H2-TYPE.           2115..2139
   PFAM                 zf-C2H2: Zinc finger, C2H2 type          406..428
   PFAM                 zf-C2H2: Zinc finger, C2H2 type          434..456
   PFAM                 zf-C2H2: Zinc finger, C2H2 type          958..981
   PFAM                 zf-C2H2: Zinc finger, C2H2 type          2087..2109
   PFAM                 zf-C2H2: Zinc finger, C2H2 type          2115..2139
   PRINTS               ZINCFINGER1: First half of finger motif  433..446
   PRINTS               ZINCFINGER2: Second half of finger motif 2102..2111
   BLOCKS               BL00028: Zinc finger, C2H2 type, domain  436..452
__________________


  Minus Strand HSPs:

 Score = 57 (26.2 bits), Expect = 21., Sum P(2) = 1.0
 Identities = 12/35 (34%), Positives = 18/35 (51%), Frame = -3

Query:   294 ICHRVKESTKPGTLVPAACQKTIEPVSHRRDAENE 190
             +CHR K    PG + P    KT+E    +  ++NE
Sbjct:   721 LCHREKALLLPGQMRPPLATKTLEERISKLISDNE 755

 Score = 45 (20.7 bits), Expect = 21., Sum P(2) = 1.0
 Identities = 8/26 (30%), Positives = 13/26 (50%), Frame = -3

Query:   552 EKCNTGVLNPNVRTPQQPCQRHHLGS 475
             E+C++  L+   RT    C   H G+
Sbjct:   161 EQCDSSSLSSKTRTDNSECISSHCGT 186


to_oldto_entto_Entrezto_Relatedto_SRSsp|Q05556|CPAB_RABIT|gi|544086 CYTOCHROME P450 IIA11 (P450-IIA11).
            Length = 494

 Cluster: 167.56 cytochrome testosterone ec p-450 coumarin p450 1.14.14.- naphthalene hydroxylase phenobarbital-inducible
 Cluster: 167.57 cytochrome p-450 testosterone ec coumarin p450 1.14.14.- naphthalene phenobarbital-inducible s-mephenytoin
 Cluster: 167.59 cytochrome p-450 testosterone ec coumarin p450 1.14.14.- naphthalene phenobarbital-inducible s-mephenytoin


Conserved regions:       
   Cluster 167.56          |_  ___  ________         ____ ____   _____|
   Cluster 167.57             |______________      |
   Cluster 167.59             | __  ___|

Local hits (HSPs):                                         ______         
Annotated Domains:      __ _______________________________________________
                        __________________________________________________
Database sequence:     |               |              |              |    | 494
                       0             150            300            450
__________________

Annotated Domains:
   Entrez               binding site: HEME.                      439
   PFAM                 p450: Cytochrome P450                    34..491
   PRINTS               EP450I1: E-class P450 group I motif I -  62..81
   PRINTS               EP450I2: E-class P450 group I motif II - 86..107
   PRINTS               EP450I3: E-class P450 group I motif III  177..195
   PRINTS               EP450I4: E-class P450 group I motif IV - 290..307
   PRINTS               P4501: P450 superfamily motif I - 4      301..318
   PRINTS               EP450I5: E-class P450 group I motif V -  310..336
   PRINTS               P4502: P450 superfamily motif II - 4     319..332
   PRINTS               EP450I6: E-class P450 group I motif VI - 353..371
   PRINTS               P4503: P450 superfamily motif III - 4    354..365
   PRINTS               EP450I7: E-class P450 group I motif VII  394..418
   PRINTS               EP450I8: E-class P450 group I motif VIII 429..439
   PRINTS               P4504: P450 superfamily motif IV - 4     430..439
   PRINTS               EP450I9: E-class P450 group I motif IX - 439..462
   PRINTS               P4505: P450 superfamily motif V - 4      439..450
   BLOCKS               BL00086: Cytochrome P450 cysteine heme-i 429..460
   PROSITE              CYTOCHROME_P450: Cytochrome P450 cystein 432..441
   PROSITE              PROKAR_LIPOPROTEIN: Prokaryotic membrane 4..14
__________________


  Plus Strand HSPs:

 Score = 63 (29.0 bits), Expect = 21., P = 1.0
 Identities = 18/57 (31%), Positives = 26/57 (45%), Frame = +1

Query:   175 PFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHS 345
             P+  A+I  +   TD     LARR  + T+F  FL P   +V   +  VL    + S
Sbjct:   350 PYTEAVIHEIQRFTDMIPMGLARRVTRDTKFRDFLLPKGTEVFPMLGSVLKDPKFFS 406


to_oldto_entto_Entrezto_Relatedto_SRSsp|P16766|UL35_HCMVA|gi|136891 HYPOTHETICAL PROTEIN UL35.
            Length = 640


Local hits (HSPs):                                           _______      
Annotated Domains:              _       _    _                            
                        __________________________________________________
Database sequence:     |           |           |           |          |   | 640
                       0         150         300         450        600
__________________

Annotated Domains:
   Entrez               glycosylation site                       208
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 106..113
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 271..277
__________________


  Minus Strand HSPs:

 Score = 63 (29.0 bits), Expect = 22., P = 1.0
 Identities = 20/75 (26%), Positives = 34/75 (45%), Frame = -2

Query:   679 DIFHHF*SFAENYAETITDQANLHAQRSNIATLTTESVPQPQRKVQYRRTQPKCSDATAA 500
             +I  H   FA+ +   +TD A+  +  S+ ++ +  SV  P  +    RT    S  T+A
Sbjct:   480 EITEHRDLFADVFRRPVTDAASSSSASSSSSSASPNSVSLPSARSSSTRTTTPASTYTSA 539

Query:   499 MPTPPSGQWFSLSQS 455
               +  +G   S S S
Sbjct:   540 GTSSTTGLLLSSSLS 554


to_oldto_entto_Entrezto_Relatedto_SRSsp|P09615|WNTG_DROME|gi|139777 PROTEIN DINT-1 PRECURSOR (WINGLESS PROTEIN).
            Length = 468

 Cluster: 546.24 wnt-11 wnt-4 wnt-1 dint-1 proto-oncogene protein wingless precursor peptide aa


Conserved regions:       
   Cluster 546.24                    |__      _______            _____ __|

Local hits (HSPs):               ___      ___                         __  
Annotated Domains:           _________________________         ___________
                        __________________________________________________
Database sequence:     |               |               |               |  | 468
                       0             150             300             450
__________________

Annotated Domains:
   Entrez               glycosylation site                       103
   Entrez               glycosylation site                       108
   Entrez               glycosylation site                       414
   PFAM                 wnt: wnt family of developmental signali 56..275
   PFAM                 wnt: wnt family of developmental signali 370..468
   BLOCKS               BL00246A: Wnt-1 family proteins.         85..104
   BLOCKS               BL00246B: Wnt-1 family proteins.         123..157
   BLOCKS               BL00246C: Wnt-1 family proteins.         180..204
   BLOCKS               BL00246D: Wnt-1 family proteins.         213..265
   BLOCKS               BL00246E: Wnt-1 family proteins.         422..467
   PROSITE              WNT1: Wnt-1 family signature.            233..242
__________________


  Plus Strand HSPs:

 Score = 43 (19.8 bits), Expect = 24., Sum P(3) = 1.0
 Identities = 7/11 (63%), Positives = 8/11 (72%), Frame = +3

Query:   585 VAIFERCACRF 617
             V + ERCAC F
Sbjct:   437 VVVVERCACTF 447

 Score = 42 (19.3 bits), Expect = 24., Sum P(3) = 1.0
 Identities = 9/19 (47%), Positives = 12/19 (63%), Frame = +1

Query:   208 AVTDWFDGFLARRWNQSTR 264
             A+++    F  RRWN STR
Sbjct:    89 AISECQHQFRNRRWNCSTR 107

 Score = 38 (17.5 bits), Expect = 24., Sum P(3) = 1.0
 Identities = 7/15 (46%), Positives = 7/15 (46%), Frame = +2

Query:   482 RWWRWHGCCGVRTFG 526
             R W W GC     FG
Sbjct:   178 RDWEWGGCSDNIGFG 192


to_oldto_entto_Entrezto_Relatedto_SRSbbs|140967|gi|455944 wingless protein=wg/wingless wgIN67 [Drosophila, Peptide
            Mutant, 468 aa]
            Length = 468


Local hits (HSPs):               ___      ___                         __  
                        __________________________________________________
Database sequence:     |               |               |               |  | 468
                       0             150             300             450

  Plus Strand HSPs:

 Score = 43 (19.8 bits), Expect = 24., Sum P(3) = 1.0
 Identities = 7/11 (63%), Positives = 8/11 (72%), Frame = +3

Query:   585 VAIFERCACRF 617
             V + ERCAC F
Sbjct:   437 VVVVERCACTF 447

 Score = 42 (19.3 bits), Expect = 24., Sum P(3) = 1.0
 Identities = 9/19 (47%), Positives = 12/19 (63%), Frame = +1

Query:   208 AVTDWFDGFLARRWNQSTR 264
             A+++    F  RRWN STR
Sbjct:    89 AISECQHQFRNRRWNCSTR 107

 Score = 38 (17.5 bits), Expect = 24., Sum P(3) = 1.0
 Identities = 7/15 (46%), Positives = 7/15 (46%), Frame = +2

Query:   482 RWWRWHGCCGVRTFG 526
             R W W GC     FG
Sbjct:   178 RDWEWGGCSDNIGFG 192


to_oldto_entto_Entrezto_Relatedto_SRSsp|P35503|UD1C_HUMAN|gi|549152 UDP-GLUCURONOSYLTRANSFERASE 1C PRECURSOR,
            MICROSOMAL (UDPGT) (UGT1C) (UGT1*3).
            Length = 534

 Cluster: 1040.13 udp-glucuronosyltransferase precursor bilirubin microsomal peptide 1a udpgt aa specific isozyme
 Cluster: 1040.14 udp-glucuronosyltransferase precursor 1f bilirubin microsomal peptide udpgt aa specific isozyme


Conserved regions:       
   Cluster 1040.13         |                     ________________________|
   Cluster 1040.14         |_        __     __________________|

Local hits (HSPs):           ___     __                                   
Annotated Domains:        ________________________________________________
                        __________________________________________________
Database sequence:     |             |             |              |       | 534
                       0           150           300            450
__________________

Annotated Domains:
   Entrez               Transmembrane region                     492..508
   Entrez               glycosylation site                       119
   Entrez               glycosylation site                       142
   Entrez               glycosylation site                       296
   Entrez               glycosylation site                       348
   PFAM                 UDPGT: UDP-glucoronosyl and UDP-glucosyl 29..526
   BLOCKS               BL00375A: UDP-glycosyltransferases prote 39..61
   BLOCKS               BL00375B: UDP-glycosyltransferases prote 128..168
   BLOCKS               BL00375C: UDP-glycosyltransferases prote 190..213
   BLOCKS               BL00375D: UDP-glycosyltransferases prote 254..281
   BLOCKS               BL00375E: UDP-glycosyltransferases prote 294..343
   BLOCKS               BL00375F: UDP-glycosyltransferases prote 349..393
   BLOCKS               BL00375G: UDP-glycosyltransferases prote 448..487
   PROSITE              UDPGT: UDP-glycosyltransferases signatur 355..398
__________________


  Minus Strand HSPs:

 Score = 52 (23.9 bits), Expect = 26., Sum P(2) = 1.0
 Identities = 10/29 (34%), Positives = 16/29 (55%), Frame = -2

Query:   640 AETITDQANLHAQRSNIATLTTESVPQPQ 554
             A  +T + N+H +  N  TLTT ++   Q
Sbjct:    58 AVVLTPEVNMHIKEENFFTLTTYAISWTQ 86

 Score = 44 (20.2 bits), Expect = 26., Sum P(2) = 1.0
 Identities = 10/22 (45%), Positives = 13/22 (59%), Frame = -1

Query:   500 HANATIWAVVFTFPIQETATLL 435
             H NAT + VV T P+   A +L
Sbjct:   140 HLNATSFDVVLTDPVNLCAAVL 161


to_oldto_entto_Entrezto_Relatedto_SRSsp|P00744|PRTZ_BOVIN|gi|131090 VITAMIN K-DEPENDENT PROTEIN Z.
            Length = 396

 Cluster: 3591.3 factor plasma vitamin k-dependent l x1 protein z precursor


Conserved regions:       
   Cluster 3591.3       |     ____   __  |

Local hits (HSPs):             _______                             _____  
Annotated Domains:      ________________ _________________________________
                        __________________________________________________
Database sequence:     |                  |                  |            | 396
                       0                150                300
__________________

Annotated Domains:
   Entrez               Domain: EGF-LIKE 1.                      47..83
   Entrez               Domain: EGF-LIKE 2.                      85..126
   Entrez               Domain: TRYPSIN-LIKE.                    143..396
   Entrez               gamma-carboxyglutamic-acid site          7
   Entrez               gamma-carboxyglutamic-acid site          8
   Entrez               gamma-carboxyglutamic-acid site          11
   Entrez               gamma-carboxyglutamic-acid site          15
   Entrez               gamma-carboxyglutamic-acid site          17
   Entrez               gamma-carboxyglutamic-acid site          20
   Entrez               gamma-carboxyglutamic-acid site          21
   Entrez               gamma-carboxyglutamic-acid site          26
   Entrez               gamma-carboxyglutamic-acid site          27
   Entrez               gamma-carboxyglutamic-acid site          30
   Entrez               gamma-carboxyglutamic-acid site          33
   Entrez               gamma-carboxyglutamic-acid site          36
   Entrez               gamma-carboxyglutamic-acid site          40
   Entrez               hydroxylation site                       64
   Entrez               glycosylation site: XYLOSE(2)-GLUCOSE.   53
   Entrez               glycosylation site                       59
   Entrez               glycosylation site                       191
   Entrez               glycosylation site                       289
   Entrez               glycosylation site                       388
   PFAM                 gla: Vitamin K-dependent carboxylation/g 6..47
   PFAM                 EGF: EGF-like domain                     51..82
   PFAM                 EGF: EGF-like domain                     89..125
   PFAM                 trypsin: Trypsin                         146..352
   PRINTS               GLABLOOD1: Coagulation factor Gla domain 5..18
   PRINTS               GLABLOOD2: Coagulation factor Gla domain 19..32
   PRINTS               GLABLOOD3: Coagulation factor Gla domain 33..47
   PRINTS               EGFBLOOD1: Type II EGF-like repeat motif 47..58
   PRINTS               EGFBLOOD2: Type II EGF-like repeat motif 59..66
   PRINTS               EGFBLOOD3: Type II EGF-like repeat motif 67..77
   PRINTS               EGFBLOOD4: Type II EGF-like repeat motif 78..84
   BLOCKS               BL00022A: EGF-like domain proteins.      56..62
   BLOCKS               BL00022B: EGF-like domain proteins.      71..77
   PROSITE              ASX_HYDROXYL: Aspartic acid and asparagi 62..73
   PROSITE              GLU_CARBOXYLATION: Vitamin K-dependent c 5..42
   PROSITE              EGF_1: EGF-like domain signature 1.      71..82
   PROSITE              EGF_2: EGF-like domain signature 2.      71..82
__________________


  Minus Strand HSPs:

 Score = 45 (20.7 bits), Expect = 30., Sum P(3) = 1.0
 Identities = 12/42 (28%), Positives = 14/42 (33%), Frame = -3

Query:   576 QSQYRSHKEKCNTGVLNPNVRTPQQPCQRHHLGSGFHFPNPG 451
             Q   R +   C  G   PN    +  C    L    HF  PG
Sbjct:    63 QDSIRGYACTCAPGYEGPNCAFAESECHPLRLDGCQHFCYPG 104

 Score = 40 (18.4 bits), Expect = 30., Sum P(3) = 1.0
 Identities = 7/20 (35%), Positives = 11/20 (55%), Frame = -1

Query:   275 KAPNRVLWFQRRARKPSNQS 216
             K P   LW ++  ++PS  S
Sbjct:   344 KVPRYALWLRQVTQQPSRAS 363

 Score = 36 (16.6 bits), Expect = 30., Sum P(3) = 1.0
 Identities = 9/19 (47%), Positives = 10/19 (52%), Frame = -3

Query:   216 SHRRDAENERGGKRRPGDR 160
             S R D    R G+  PGDR
Sbjct:   363 SPRGDRGQGRDGEPVPGDR 381


to_oldto_entto_Entrezto_Relatedto_SRSsp|P09346|KNOB_PLAFG|gi|125516 KNOB-ASSOCIATED HISTIDINE-RICH PROTEIN
            PRECURSOR (KAHRP).
            Length = 634


Local hits (HSPs):                               __    ____               
Annotated Domains:         _______ ____       __     ______       ____    
                        __________________________________________________
Database sequence:     |           |           |           |           |  | 634
                       0         150         300         450         600
__________________

Annotated Domains:
   Entrez               Domain: HIS-RICH.                        61..116
   Entrez               Domain: 13 AA TANDEM REPEATS.            370..438
   Entrez               Domain: 4 X 10 AA APPROXIMATE TANDEM REP 540..580
   Entrez               glycosylation site                       42
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 152..158
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 173..180
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 174..180
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 292..299
__________________


  Minus Strand HSPs:

 Score = 59 (27.1 bits), Expect = 31., Sum P(2) = 1.0
 Identities = 12/39 (30%), Positives = 20/39 (51%), Frame = -3

Query:   204 DAENERGGKRRPGDRQIKDQYKEWDKDDTEQCKQRRDIK 88
             DAE+ +  K +  D + K   K  D +D E  K ++ +K
Sbjct:   400 DAESVKSKKHKSHDCEKKKSKKHKDNEDAESVKSKKSVK 438

 Score = 37 (17.0 bits), Expect = 31., Sum P(2) = 1.0
 Identities = 7/12 (58%), Positives = 7/12 (58%), Frame = -2

Query:   271 HQTGYSGSSGVP 236
             H  GYS   GVP
Sbjct:   323 HGAGYSAPYGVP 334


to_oldto_entto_Entrezto_Relatedto_SRSsp|P13818|KNOB_PLAFX|gi|125518 KNOB-ASSOCIATED HISTIDINE-RICH PROTEIN
            PRECURSOR (KAHRP) (KP).
            Length = 634


Local hits (HSPs):                               __    ____               
Annotated Domains:         _______ ____       __     ______       ____    
                        __________________________________________________
Database sequence:     |           |           |           |           |  | 634
                       0         150         300         450         600
__________________

Annotated Domains:
   Entrez               Domain: HIS-RICH.                        61..116
   Entrez               Domain: 13 AA TANDEM REPEATS.            370..438
   Entrez               Domain: 4 X 10 AA APPROXIMATE TANDEM REP 540..580
   Entrez               glycosylation site                       42
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 152..158
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 173..180
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 174..180
   PROSITE              TYR_PHOSPHO_SITE: Tyrosine kinase phosph 292..299
__________________


  Minus Strand HSPs:

 Score = 59 (27.1 bits), Expect = 31., Sum P(2) = 1.0
 Identities = 12/39 (30%), Positives = 20/39 (51%), Frame = -3

Query:   204 DAENERGGKRRPGDRQIKDQYKEWDKDDTEQCKQRRDIK 88
             DAE+ +  K +  D + K   K  D +D E  K ++ +K
Sbjct:   400 DAESVKSKKHKSHDCEKKKSKKHKDNEDAESVKSKKSVK 438

 Score = 37 (17.0 bits), Expect = 31., Sum P(2) = 1.0
 Identities = 7/12 (58%), Positives = 7/12 (58%), Frame = -2

Query:   271 HQTGYSGSSGVP 236
             H  GYS   GVP
Sbjct:   323 HGAGYSAPYGVP 334


to_oldto_entto_Entrezto_Relatedto_SRSgi|488833 zinc finger protein 51
           Length = 710

 Cluster: 28.54 gastrula oocyte zinc finger protein 51 xlcgf58.1 xlcof22
 Cluster: 28.107 gastrula oocyte znf37a zinc finger protein zfp-37 znf133 znf140 xlcof8.4
 Cluster: 28.141 gastrula oocyte zinc-finger transcriptional zinc finger putative protein mkr5 placental


Conserved regions:       
   Cluster 28.54                               | _  __ _ __ _____  ____|
   Cluster 28.107                                  |_______     |
   Cluster 28.141                                  |     ___|

Local hits (HSPs):      ____                                  __       ___
                        __________________________________________________
Database sequence:     |          |          |         |          |       | 710
                       0        150        300       450        600

  Minus Strand HSPs:

 Score = 50 (23.0 bits), Expect = 32., Sum P(3) = 1.0
 Identities = 9/30 (30%), Positives = 17/30 (56%), Frame = -3

Query:   546 CNTGVLNPNVRTPQQPCQRHHLGSGFHFPN 457
             C    ++ +V+T ++ CQ + LG   H P+
Sbjct:    15 CICDTVHQHVKTEKESCQGNKLGEMLHEPS 44

 Score = 39 (17.9 bits), Expect = 32., Sum P(3) = 1.0
 Identities = 8/22 (36%), Positives = 11/22 (50%), Frame = -3

Query:   240 CQKTIEPVSHRRDAENERGGKR 175
             C K+   VSH R  +    G+R
Sbjct:   541 CDKSFTQVSHLRTHQRVHTGER 562

 Score = 36 (16.6 bits), Expect = 32., Sum P(3) = 1.0
 Identities = 6/19 (31%), Positives = 12/19 (63%), Frame = -3

Query:   138 EWDKDDTEQCKQRRDIKLH 82
             E+DK +T+    +R  ++H
Sbjct:   680 EYDKPNTQDSNLKRHQRVH 698


to_oldto_entto_Entrezto_Relatedto_SRSprf||1705218D|gi|227508 Wnt-6 gene
            Length = 365

 Cluster: 76.93 wingless wnt-1 wnt-2 wnt-6 wnt-b xwnt-6 gene protein rerio precursor


Conserved regions:       
   Cluster 76.93                                      |___    _______ |

Local hits (HSPs):                ___         ___                   ___   
                        __________________________________________________
Database sequence:     |                    |                   |         | 365
                       0                  150                 300

  Plus Strand HSPs:

 Score = 47 (21.6 bits), Expect = 33., Sum P(3) = 1.0
 Identities = 9/21 (42%), Positives = 12/21 (57%), Frame = +3

Query:   555 CGCGTDSVVNVAIFERCACRF 617
             CG G  +  +V + E C CRF
Sbjct:   324 CGRGHRAQESVQLEENCLCRF 344

 Score = 37 (17.0 bits), Expect = 33., Sum P(3) = 1.0
 Identities = 8/15 (53%), Positives = 9/15 (60%), Frame = +1

Query:   232 FLARRWNQSTRFGAF 276
             F  RRWN S+   AF
Sbjct:    79 FRFRRWNCSSHSKAF 93

 Score = 36 (16.6 bits), Expect = 33., Sum P(3) = 1.0
 Identities = 6/13 (46%), Positives = 6/13 (46%), Frame = +2

Query:   488 WRWHGCCGVRTFG 526
             W W GC     FG
Sbjct:   166 WEWGGCGDDVDFG 178


to_oldto_entto_Entrezto_Relatedto_SRSgi|347377 MLL-AF4 der(11) fusion protein
           Length = 2311


Local hits (HSPs):                    _                    _        __    
                        __________________________________________________
Database sequence:     |          |          |          |          |      | 2311
                       0        500       1000       1500       2000

  Minus Strand HSPs:

 Score = 46 (21.2 bits), Expect = 35., Sum P(3) = 1.0
 Identities = 8/17 (47%), Positives = 11/17 (64%), Frame = -2

Query:   487 PSGQWFSLSQSRRRPRY 437
             P+ +W SL  SR  P+Y
Sbjct:   656 PTFRWTSLKHSRSEPQY 672

 Score = 43 (19.8 bits), Expect = 35., Sum P(3) = 1.0
 Identities = 11/27 (40%), Positives = 14/27 (51%), Frame = -1

Query:   245 RRARKPSNQSVTAATQKMSAAANGDQV 165
             R  R P  QS    TQ++ AAA   +V
Sbjct:  1628 RHQRAPGAQSPHGGTQRVRAAATVPRV 1654

 Score = 43 (19.8 bits), Expect = 35., Sum P(3) = 1.0
 Identities = 10/36 (27%), Positives = 18/36 (50%), Frame = -3

Query:   183 GKRRPGDRQIKDQYKEWDKDDTEQCKQRRDIKLHND 76
             G  +PG  Q+K   ++ D    E+ K ++  +L  D
Sbjct:  2048 GNSKPGKPQVKFDKQQADLHMREEKKMKQKAELMTD 2083


to_oldto_entto_Entrezto_Relatedto_SRSgi|443822 H,K-ATPase
           Length = 1042

 Cluster: 217.43 sodium/potassium-transporting sodium alpha-1 alpha atpase chain subunit proton pump na+/k+
 Cluster: 217.44 sodium/potassium-transporting sodium alpha-1 alpha atpase chain subunit proton pump na+/k+
 Cluster: 217.45 sodium/potassium-transporting sodium alpha-1 alpha atpase chain subunit k+ pump na+/k+


Conserved regions:       
   Cluster 217.43              |  ____  ____     _  ___  ______     _|
   Cluster 217.44              |_ ____  ____     _ |
   Cluster 217.45                    |  ____     |

Local hits (HSPs):                           _         __           ___   
                        __________________________________________________
Database sequence:     |       |      |      |      |      |       |      | 1042
                       0     150    300    450    600    750     900

  Plus Strand HSPs:

 Score = 44 (20.2 bits), Expect = 37., Sum P(3) = 1.0
 Identities = 12/42 (28%), Positives = 19/42 (45%), Frame = +1

Query:   523 WVEYAGIALFFVAAVLTLWSMLQYLSAARADLLDQ*SFRRNF 648
             ++E+ G   FFV+ V+   + L      R  +  Q  FR  F
Sbjct:   931 FLEWTGYTAFFVSIVVEQLADLIIRKTRRNSVFQQGLFRNKF 972

 Score = 43 (19.8 bits), Expect = 37., Sum P(3) = 1.0
 Identities = 11/33 (33%), Positives = 19/33 (57%), Frame = +1

Query:   391 IISALREWMAELGKRSSVAVSWIGKVKTTAQMV 489
             IISA  E + ++ KR ++ V  + K +  A +V
Sbjct:   651 IISAGSETVDDIAKRLNIPVEQVNKREAKAAVV 683

 Score = 40 (18.4 bits), Expect = 37., Sum P(3) = 1.0
 Identities = 6/12 (50%), Positives = 9/12 (75%), Frame = +3

Query:   162 CHLVAVCRRAHF 197
             C +V++C RA F
Sbjct:   440 CKIVSLCNRAEF 451


to_oldto_entto_Entrezto_Relatedto_SRSgi|218415 phosphatidylserine synthase
           Length = 276


Local hits (HSPs):                          _________                     
                        __________________________________________________
Database sequence:     |        |        |        |         |        |    | 276
                       0       50      100      150       200      250

  Plus Strand HSPs:

 Score = 61 (28.1 bits), Expect = 37., P = 1.0
 Identities = 16/44 (36%), Positives = 23/44 (52%), Frame = +1

Query:   184 AALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIA 315
             A     +A   D+ DG +AR  N+S+  G  LD +AD V   +A
Sbjct:   116 AHFFILLAMCFDFLDGRVARLRNRSSLMGQELDSLADLVSFGVA 159


to_oldto_entto_Entrezto_Relatedto_SRSgi|530088 aminoalcoholphosphotransferase
           Length = 389

 Cluster: 4944.3 aminoalcoholphosphotransferase ethanolaminephosphotransferase saccharomyces cerevisiae ethpt diacylglycerol sn-1 cholinephosphotransferase 2-diacylglycerol chopt


Conserved regions:       
   Cluster 4944.3       |_______ ________  _____              _|

Local hits (HSPs):               _______                                  
                        __________________________________________________
Database sequence:     |                   |                  |           | 389
                       0                 150                300

  Plus Strand HSPs:

 Score = 61 (28.1 bits), Expect = 39., P = 1.0
 Identities = 16/45 (35%), Positives = 19/45 (42%), Frame = +1

Query:   160 PVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVAD 294
             P  W  FA  L+  +    D  DG  ARR N S+  G   D   D
Sbjct:    76 PPRWVHFAHGLLLFLYQTFDAVDGKQARRTNSSSPLGELFDHGCD 120


to_oldto_entto_Entrezto_Relatedto_SRSgi|580702 fixP
           Length = 293

 Cluster: 4770 ccop fixp fixp=membrane-anchored diheme cytochrome symbiotic nitrogen fixation gene cluster


Conserved regions:       
   Cluster 4770            |_______          _____           ______ __ __|

Local hits (HSPs):           __       ____                                
                        __________________________________________________
Database sequence:     |        |       |        |       |        |       | 293
                       0       50     100      150     200      250

  Plus Strand HSPs:

 Score = 54 (24.8 bits), Expect = 41., Sum P(2) = 1.0
 Identities = 7/8 (87%), Positives = 7/8 (87%), Frame = +2

Query:   473 PLPRWWRW 496
             PLPRWW W
Sbjct:    34 PLPRWWLW 41

 Score = 38 (17.5 bits), Expect = 41., Sum P(2) = 1.0
 Identities = 9/21 (42%), Positives = 14/21 (66%), Frame = +2

Query:   809 DLAKVGVASSSLVSRSSLKDI 871
             DL K+  ASS+ ++   L+DI
Sbjct:    85 DLQKLRAASSAKLANVPLEDI 105


to_oldto_entto_Entrezto_Relatedto_SRSsp|P10327|CRYW_BACTA|gi|117546 130 KD CRYSTAL PROTEIN (DELTA ENDOTOXIN)
            (CRYSTALINE ENTOMOCIDAL PROTOXIN).
            Length = 823

 Cluster: 198.50 130 parasporal kd protein crystal delta endotoxin crystaline entomocidal protoxin
 Cluster: 198.53 130 parasporal kd protein crystal delta endotoxin crystaline entomocidal protoxin


Conserved regions:       
   Cluster 198.50          |___ ___ _______         ________________|
   Cluster 198.53                                | __       ________|

Local hits (HSPs):                            __                          
Annotated Domains:      ______________________________________            
                        __________________________________________________
Database sequence:     |         |        |        |        |        |    | 823
                       0       150      300      450      600      750
__________________

Annotated Domains:
   PFAM                 endotoxin: delta endotoxin               1..616
__________________


  Minus Strand HSPs:

 Score = 61 (28.1 bits), Expect = 42., P = 1.0
 Identities = 10/14 (71%), Positives = 11/14 (78%), Frame = -3

Query:   525 PNVRTPQQPCQRHH 484
             P +R  QQPCQRHH
Sbjct:   367 PTLRLLQQPCQRHH 380


to_oldto_entto_Entrezto_Relatedto_SRSgi|490199 lepidoptera larvicidal protein
           Length = 823

 Cluster: 198.50 130 parasporal kd protein crystal delta endotoxin crystaline entomocidal protoxin
 Cluster: 198.53 130 parasporal kd protein crystal delta endotoxin crystaline entomocidal protoxin


Conserved regions:       
   Cluster 198.50          |___ ___ _______         ________________|
   Cluster 198.53                                | __       ________|

Local hits (HSPs):                            __                          
                        __________________________________________________
Database sequence:     |         |        |        |        |        |    | 823
                       0       150      300      450      600      750

  Minus Strand HSPs:

 Score = 61 (28.1 bits), Expect = 42., P = 1.0
 Identities = 10/14 (71%), Positives = 11/14 (78%), Frame = -3

Query:   525 PNVRTPQQPCQRHH 484
             P +R  QQPCQRHH
Sbjct:   367 PTLRLLQQPCQRHH 380


to_oldto_entto_Entrezto_Relatedto_SRSgi|291529 tegument protein
           Length = 841

 Cluster: 7006.2 positional tegument transcriptional regulator homolog ie63 of protein icp27 ul69


Conserved regions:       
   Cluster 7006.2                |   _____  __ _ |

Local hits (HSPs):                                         ___            
                        __________________________________________________
Database sequence:     |        |        |        |        |        |     | 841
                       0      150      300      450      600      750

  Minus Strand HSPs:

 Score = 61 (28.1 bits), Expect = 42., P = 1.0
 Identities = 17/38 (44%), Positives = 19/38 (50%), Frame = -2

Query:   556 QRKVQYRRTQPKCSDATAAMPTPPSGQWFSLSQSRRRP 443
             Q+  Q   T  K S  TAAMP PPS    S +   RRP
Sbjct:   595 QQSQQQPETTSKESSKTAAMPPPPSPCSPSPASRERRP 632


to_oldto_entto_Entrezto_Relatedto_SRSsp|P31287|WNT6_XENLA|gi|401424 XWNT-6 PROTEIN.
            Length = 129

 Cluster: 76.93 wingless wnt-1 wnt-2 wnt-6 wnt-b xwnt-6 gene protein rerio precursor


Conserved regions:       
   Cluster 76.93           |________            _____   __________     |

Local hits (HSPs):       _____________                        ___________ 
Annotated Domains:      __________________________________________________
                        __________________________________________________
Database sequence:     |                  |                   |           | 129
                       0                 50                 100
__________________

Annotated Domains:
   Entrez               glycosylation site                       92
   PFAM                 wnt: wnt family of developmental signali 1..129
   PROSITE              WNT1: Wnt-1 family signature.            3..12
__________________


  Plus Strand HSPs:

 Score = 44 (20.2 bits), Expect = 44., Sum P(2) = 1.0
 Identities = 10/33 (30%), Positives = 15/33 (45%), Frame = +3

Query:   141 CIGLLSACHLVAVCRRAHFLRRGGD*LVRWFSG 239
             C GL  +C      ++    R  GD L+  F+G
Sbjct:     5 CHGLSGSCTFTTCWKKMPHFREVGDRLLERFNG 37

 Score = 43 (19.8 bits), Expect = 44., Sum P(2) = 1.0
 Identities = 9/25 (36%), Positives = 10/25 (40%), Frame = +3

Query:   543 CTFLCGCGTDSVVNVAIFERCACRF 617
             C  LC         V + E C CRF
Sbjct:   101 CDLLCCGRGQREETVVVEENCLCRF 125


Parameters:
  -gi
  -echofilter
  H=1
  E=50
  V=50
  B=50

  -ctxfactor=6.00

  Query                        -----  As Used  -----    -----  Computed  ----
  Frame  MatID Matrix name     Lambda    K       H      Lambda    K       H
   Std.    0   BLOSUM62                                 0.319   0.135   0.396
   +3      0   BLOSUM62        0.319   0.135   0.396    0.362   0.162   0.608
   +2      0   BLOSUM62        0.319   0.135   0.396    0.348   0.151   0.559
   +1      0   BLOSUM62        0.319   0.135   0.396    0.341   0.147   0.485
   -1      0   BLOSUM62        0.319   0.135   0.396    0.340   0.141   0.447
   -2      0   BLOSUM62        0.319   0.135   0.396    0.350   0.152   0.529
   -3      0   BLOSUM62        0.319   0.135   0.396    0.333   0.143   0.459

  Query
  Frame  MatID  Length  Eff.Length   E    S W   T  X     E2  S2
   +3      0      318       318      50. 56 3  12 22    0.10 36
   +2      0      318       318      50. 56 3  12 22    0.10 36
   +1      0      318       318      50. 56 3  12 22    0.10 36
   -1      0      318       318      50. 56 3  12 22    0.10 36
   -2      0      318       318      50. 56 3  12 22    0.10 36
   -3      0      318       318      50. 56 3  12 22    0.10 36


Statistics:
  Query          Expected         Observed           HSPs       HSPs
  Frame  MatID  High Score       High Score       Reportable  Reported
   +3      0    65 (29.9 bits)   63 (29.0 bits)         9          9
   +2      0    65 (29.9 bits)   57 (26.2 bits)        11         11
   +1      0    65 (29.9 bits)  945 (434.7 bits)       23         23
   -1      0    65 (29.9 bits)   59 (27.1 bits)         5          5
   -2      0    65 (29.9 bits)   66 (30.4 bits)        20         20
   -3      0    65 (29.9 bits)   61 (28.1 bits)        19         19

  Query         Neighborhd  Word      Excluded    Failed   Successful  Overlaps
  Frame  MatID   Words      Hits        Hits    Extensions Extensions  Excluded
   +3      0      5118     9567919     1875177     7689369     3373         0
   +2      0      6067     9861874     2095365     7760966     5543         5
   +1      0      5374     9031376     1875308     7149673     6395         7
   -1      0      3767     7828582     1291609     6531023     5950         5
   -2      0      4274     9510270     1839648     7663878     6744        51
   -3      0      5420    10605557     2059057     8539356     7144        22

  Database:  /local/dot5/sl_home/beauty/seqdb/blast-db/CRSeqAnnot.fa
    Release date:  unknown
    Posted date:  4:10 PM CDT Jun 27, 1995
  # of letters in database:  28,902,124
  # of sequences in database:  78,469
  # of database sequences satisfying E:  42
  No. of states in DFA:  596 (59 KB)
  Total size of DFA:  326 KB (384 KB)
  Time to generate neighborhood:  0.03u 0.01s 0.04t  Real: 00:00:00
  No. of processors used:  4
  Time to search database:  92.89u 0.10s 92.99t  Real: 00:00:31

Back to BCM Search Launcher: Protein Sequence/Pattern Searches

Kim C. Worley and Michael McLeod, Human Genome Sequencing Center, Baylor College of Medicine
Email
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BCM HGSC