Borrelia burgdorferi Genome
Sequence Search
>Query : 1125 aa
vs library
using protein matrix
432633 residues in 1639 sequences
statistics exclude scores greater than 77
mean initn score: 38.0 (11.55)
mean init1 score: 35.0 (7.30)
1639 scores better than 1 saved, ktup: 2, variable pamfact
joining threshold: 32
The best scores are: initn init1 opt
BB0623 transcription-repair coupling factor (mfd) {Hae 5434 5434 5434
BB0581 DNA recombinase (recG) {Synechocystis PCC6803} 580 350 625
BB0071 hypothetical protein 111 74 77
BB0598 UDP-N-acetylmuramate dehydrogenase (murB) {Baci 99 56 58
BB0512 hypothetical protein 97 43 113
BB0154 preprotein translocase subunit (secA) {Borrelia 95 49 70
BB0400 hypothetical protein 92 41 54
BB0355 transcription factor, putative {Myxococcus xant 91 69 69
BB0828 DNA topoisomerase I (topA) {Synechocystis PCC68 91 54 62
BBK52 protein p23 {Borrelia burgdorferi} 89 46 51
BB0844 hypothetical protein 89 52 63
BB0836 excinuclease ABC, subunit B (uvrB) {Escherichia 88 45 136
BB0237 apolipoprotein N-acyltransferase, putative {Hae 88 41 53
BB0723 adenylyl cyclase, CyaB-type, putative {Methanoc 87 49 70
BB0569 hypothetical protein 85 61 94
BB0633 exodeoxyribonuclease V, beta chain (recB) {Haem 85 53 124
BB0707 hypothetical protein 85 40 53
BB0228 conserved hypothetical protein {Saccharomyces c 83 69 106
BB0536 zinc protease, putative {Haemophilus influenzae 83 62 71
BB0329 oligopeptide ABC transporter, periplasmic oligo 83 45 54
BB0674 hypothetical protein 82 46 58
BB0421 hydrolase {Haemophilus influenzae} 79 54 95
BBB26 hypothetical protein 79 51 53
BB0729 glutamate transporter (gltP) {Bacillus stearoth 79 50 65
BB0814 pantothenate permease (panF) {Escherichia coli} 78 42 47
BB0359 carboxyl-terminal protease (ctp) {Synechocystis 78 61 61
BBH18 hypothetical protein 78 60 88
BB0058 hypothetical protein 78 54 72
BB0646 hypothetical protein 77 41 50
BB0081 conserved hypothetical protein {Helicobacter py 77 55 60
BB0665 hypothetical protein 77 55 62
BB0447 Na+/H+ antiporter (napA) {Enterococcus hirae} 76 60 60
BB0827 ATP-dependent helicase (hrpA) {Escherichia coli 76 49 49
BB0772 flagellar P-ring protein (flgI) {Agrobacterium 75 48 50
BB0613 ATP-dependent protease LA (lon-2) {Haemophilus 75 49 49
BBI16 hypothetical protein 75 75 91
BBS35 plasmid partition protein, putative {Bacillus su 75 62 65
BB0369 ATP-dependent Clp protease, subunit A (clpA) {E 75 48 71
BB0573 ABC transporter, ATP-binding protein {Bacillus 75 46 50
BB0035 DNA topoisomerase IV (parC) {Borrelia burgdorfe 74 48 73
BB0793 thymidylate kinase (tmk) {Methanococcus jannasc 74 42 60
BB0552 DNA ligase (lig) {Thermus aquaticus} 74 56 66
BB0248 oligoendopeptidase F (pepF) {Lactococcus lactis 74 43 55
BB0045 P115 protein {Mycoplasma hyorhinis} 74 35 66
BB0373 hypothetical protein 74 56 56
BB0790 hypothetical protein 73 43 49
BB0361 minD-related ATP-binding protein (ylxH-2) {Baci 72 55 59
BB0722 hypothetical protein 72 40 57
BB0208 hypothetical protein 72 51 57
BB0214 translation elongation factor P (efp) {Escheric 71 54 77
BB0623 transcription-repair coupling factor (mfd) {Haemophilus influenzae}
100.0% identity in 1125 aa overlap
10 20 30 40 50 60
Query MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGYEGFFKAFLIKKIKEYSKTGKIILIV
X:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGYEGFFKAFLIKKIKEYSKTGKIILIV
10 20 30 40 50 60
70 80 90 100 110 120
Query KDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGIYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 KDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGIYI
70 80 90 100 110 120
130 140 150 160 170 180
Query TVLKSLLSKIPDKNTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 TVLKSLLSKIPDKNTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVKGE
130 140 150 160 170 180
190 200 210 220 230 240
Query IIDIYPFGEQNPIRIALNFDKIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDKTINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 IIDIYPFGEQNPIRIALNFDKIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDKTINT
190 200 210 220 230 240
250 260 270 280 290 300
Query LKTKIKSVEYKKILEELDFKKETKTEEMFYPLVANTYLGDEIEKHTPIVNFEINNFEKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 LKTKIKSVEYKKILEELDFKKETKTEEMFYPLVANTYLGDEIEKHTPIVNFEINNFEKEI
250 260 270 280 290 300
310 320 330 340 350 360
Query EKIHQEYEKLYKEAEEAGKNIIDPKRILLNYKTFNLKSDVLFSKIKSLKSKETIEFKIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 EKIHQEYEKLYKEAEEAGKNIIDPKRILLNYKTFNLKSDVLFSKIKSLKSKETIEFKIES
310 320 330 340 350 360
370 380 390 400 410 420
Query ERNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 ERNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLI
370 380 390 400 410 420
430 440 450 460 470 480
Query IEKEKIAIILESNIFNTGQKINKAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 IEKEKIAIILESNIFNTGQKINKAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKR
430 440 450 460 470 480
490 500 510 520 530 540
Query IKTSSLEKDYIEIEYAEGEKLFIPIEQTNLIQKYIGSDPKNIKLDKISSKTWIKNKANAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 IKTSSLEKDYIEIEYAEGEKLFIPIEQTNLIQKYIGSDPKNIKLDKISSKTWIKNKANAK
490 500 510 520 530 540
550 560 570 580 590 600
Query KRIEEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFPYDETPDQIRAIKEIKEDMMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 KRIEEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFPYDETPDQIRAIKEIKEDMMS
550 560 570 580 590 600
610 620 630 640 650 660
Query FKVMDRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSPTTILAEQHFNTFKKRFKNFPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 FKVMDRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSPTTILAEQHFNTFKKRFKNFPI
610 620 630 640 650 660
670 680 690 700 710 720
Query KIEVLSRFIKNNAESRILKELKSGKIDIIIGTHKILSKKFTCKNLGLIIIDEEQRFGVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 KIEVLSRFIKNNAESRILKELKSGKIDIIIGTHKILSKKFTCKNLGLIIIDEEQRFGVKE
670 680 690 700 710 720
730 740 750 760 770 780
Query KEKLKEIRISVDCLALSATPIPRSLHMSLIKLRDISVLKIPPQNRVKIEAYLESFSELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 KEKLKEIRISVDCLALSATPIPRSLHMSLIKLRDISVLKIPPQNRVKIEAYLESFSELLI
730 740 750 760 770 780
790 800 810 820 830 840
Query KHAIESELSRDGQVFLVNHNIEELYYLKTLIERLTPYARIAIIHGKLTGEEIENIMHNFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 KHAIESELSRDGQVFLVNHNIEELYYLKTLIERLTPYARIAIIHGKLTGEEIENIMHNFI
790 800 810 820 830 840
850 860 870 880 890 900
Query KKAYQILLATTIIENGIDIPNANTIIINNANKFGLAQLYQLKGRVGRGSQKAYAYFLYQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 KKAYQILLATTIIENGIDIPNANTIIINNANKFGLAQLYQLKGRVGRGSQKAYAYFLYQD
850 860 870 880 890 900
910 920 930 940 950 960
Query SEKLNERSIERLRAITEFSELGAGFKIAMKDMEIRGVGNLLGREQHGEIESIGLDYYLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 SEKLNERSIERLRAITEFSELGAGFKIAMKDMEIRGVGNLLGREQHGEIESIGLDYYLTM
910 920 930 940 950 960
970 980 990 1000 1010 1020
Query LNKAIEKKMGKISSDEEEVDIKINYSGFIPENYAKNEQDKILIYKKIFKIQTEEESKKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 LNKAIEKKMGKISSDEEEVDIKINYSGFIPENYAKNEQDKILIYKKIFKIQTEEESKKIR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
Query SELHNDFGPIPEEINSLLMLAELKILAKDLNITKLKEKNRALEIEYKNIESIPMEKIIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BB0623 SELHNDFGPIPEEINSLLMLAELKILAKDLNITKLKEKNRALEIEYKNIESIPMEKIIEI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
Query LQKHPNLLILNPSYQKSIFLSFKNIEKSEKINYIYKNINLLKTST
::::::::::::::::::::::::::::::::::::::::::::X
BB0623 LQKHPNLLILNPSYQKSIFLSFKNIEKSEKINYIYKNINLLKTST
1090 1100 1110 1120
BB0581 DNA recombinase (recG) {Synechocystis PCC6803}
30.9% identity in 572 aa overlap
370 380 390 400 410 420
Query ERNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLI
..: :..:: . :.. . ..:.: ......
BB0581 RQNIQTFPDFSKVKSCDMMTVFTVLGHKKFGDSSKKNLKLTVKSINEEPFEILLFNRAFL
50 60 70 80 90 100
430 440 450 460 470
Query IEKEKIAIILESNIFNTGQKINKAFES-SKTKAIDSFVEIEKNSHVVHINHGIGIFRQIK
. :: ..... .. . ..... . ...:: : .: .. .: . .. ..
BB0581 ENVFKI----DKKFYIYSKFTYNDYSGLWSCSNFDSEVYSDKPERFKKILPVYSLTEGLT
110 120 130 140 150 160
480 490 500 510 520 530
Query RIKTSSLEKDYIEIEYAEGEKLFIPIEQTNLIQKYIGSDPKNIKLDKISSKTWIKNKANA
. :.: :. .: . :.. . .. ::.:: . . . :..: . .. ..:
BB0581 SKKISLYVKEALEYFFKFGQTDIPRF----LIEKY-SLLSLSDALKEIHFPSSLEMLEKA
170 180 190 200 210
540 550 560 570 580 590
Query KKRIEEIADKLIELYSKRESIKGIKYPEDNEL--QLL--FESEFPYDETPDQIRAIKEIK
:: . . :....:. : : : ..:...: .:: :..:.. : X: .:.::
BB0581 KKTLIYREIFLLQFFSRYRSSK-ILFREKKDLSKDLLEKVVSSLPFELTEDQKISIDEIF
220 230 240 250 260 270
600 610 620 630 640 650
Query EDMMSFKVMDRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSPTTILAEQHFNTFKKRF
:. : : :.::: :::: ::: ::. ... . .. :: ..::..:: ::...... .
BB0581 FDLNSSKPMNRLLQGDVGSGKTLVALLSGLPLIEAGYQVAFMAPTDLLARQHYDNLSNIL
280 290 300 310 320 330
660 670 680 690 700 710
Query KNFPIKIEVLSRFIKNNAESRILKELKSGKIDIIIGTHKILSKKFTCKNLGLIIIDEEQR
: :....:. ........ :.....:. ..:.::: :. .. . :.:. .::::...
BB0581 APFNISMTLLTGSLRKKDKEQALESIRNGTSGLIVGTHAIFYESTEFKRLAYVIIDEQHK
340 350 360 370 380 390
720 730 740 750 760 770
Query FGVKEKEKLKEIRISVDCLALSATPIPRSLHMSLIKLRDISVLKIPPQNRVKIEAYLESF
::: ..:.::. .:: : .::::::::. ..:. ..: .:. :..:. :..:X..
BB0581 FGVVQREELKNKGEGVDMLLMSATPIPRSFALTLFGDLEVSFIKTLPKGRLPITTYLARH
400 410 420 430 440 450
780 790 800 810 820
Query -SELLIKHAIESELSRDGQVFLVNHNI--EELYYLK-------TLIERLTPYARIAIIHG
.: . . . .:: .. ::..: . : .: . :: .: : .. :. ....:.
BB0581 GNEDKVYEFLRKELLKGHQVYFVYPLISSSEKFELKDVNNMCLKLKEVFGEYV-VDMLHS
460 470 480 490 500 510
830 840 850 860 870 880
Query KLTGEEIENIMHNFIKKAYQILLATTIIENGIDIPNANTIIINNANKFGLAQLYQLKGRV
::... :.::.:: .: .::.::..:: ::: :::. .....:..:::. :.:..:::
BB0581 KLPSDLKEEIMKNFYSKKVDILVATSVIEVGIDCPNATCMVVEHAERFGLSTLHQIRGRV
520 530 540 550 560 570
890 900 910 920 930 940
Query GRGSQKAYAYFLYQDSEKLNERSIERLRAITEFSELGAGFKIAMKDMEIRGVGNLLGREQ
::.. ... ..::... :.. . ::..:.: . ::::: .:. .:: :::.: ::
BB0581 GRSNLQSFFFLLYKEP--LTSAGKFRLKTIKENLD---GFKIAEEDLRLRGPGNLFGLEQ
580 590 600 610 620
950 960 970 980 990 1000
Query HGEIESIGLDYYLTMLNKAIEKKMGKISSDEEEVDIKINYSGFIPENYAKNEQDKILIYK
:
BB0581 AGYLKLKIANFVDDREIIVLVREELDLFFYDNSAYDKLDIDLLDNLFCSYLNAGRSI
630 640 650 660 670 680
BB0071 hypothetical protein
29.4% identity in 68 aa overlap
1020 1030 1040 1050 1060 1070
Query SKKIRSELHNDFGPIPEEINSLLMLAELKILAKDLNITKLKEKNRALEIEYKNIESIPME
..X:.. . .. :: .::. :.. .. ..
BB0071 NKDMPNIIGYLSHILYQNELKYNITAKYGKIPKDIKENYFEIKNDKIEIHPKTVYEVDKS
360 370 380 390 400 410
1080 1090 1100 1110 1120
Query KIIEILQKHPNLLILNPSYQKSIFLSFKNIEKSEKINYIYKNINLLKTST
: :::.:. . :.:. . . :. . :: ...: :X
BB0071 FIDEILKKDLASLFLKNKNPILIYKENKNNINTDKKNYKILFFFSLPFFVLLFLFKAIRF
420 430 440 450 460 470
BB0071 TILLNINEKTYKKYIQG
480 490
BB0598 UDP-N-acetylmuramate dehydrogenase (murB) {Bacillus subtilis}
31.4% identity in 35 aa overlap
370 380 390 400 410 420
Query RNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLII
: .X:..:: .. ... .. .:::. .:
BB0598 WMNARCFGNEISEILKKITFIDDKGKTICKEFKKEDFKYKISPFQNKNFFILKIELNLKK
140 150 160 170 180 190
430 440 450 460 470 480
Query EKEKIAIILESNIFNTGQKINKAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKRI
...:X
BB0598 DNKKIIEEKMNKNKQARINRGHYLFPSGGSTFKNNKAFLKPSGQIIEECKLKGLSIGGAT
200 210 220 230 240 250
BB0512 hypothetical protein
17.4% identity in 534 aa overlap
60 70 80 90 100 110
Query IVKDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKF-------LFNF
.::. ...: ... :: : .:
BB0512 MIDFATILVNLFLVSIVLFVYRQYDKRSRALDKIKKFVDLTKVNLEDF
10 20 30 40
120 130 140 150 160 170
Query YKKNPGIYITVLKSLLSKIPDKNTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTI
.... .. .. . ... ...:.: ....... ...:.... ...:.... ..
BB0512 IEDKTKEINDLAVDMEAYQRSSIEIIKKIEEVQQKIKNKSNDFAEVEKKIAYHDSMLKDL
50 60 70 80 90 100
180 190 200 210 220
Query PG-EFTVKGEI--IDIYPFGEQNPIRIALNFDKIEEIKKFNPLTQLKHDNEILEFQILPK
. .:.:...: ... .. .. .:.. . . : . :.. .. . .. .
BB0512 DEMTFKVQENIQRLQVDGKIVDKLSKTLKGFNTQIDSVESNLNSVLEKFDKANKENLESI
110 120 130 140 150 160
230 240 250 260 270 280
Query KEIIWD--DKTINTLKTKIKSVEYKKILEELDFKK-ETKTEEMFYPLVANTYLGDEIEKH
: :. :..:..: ::.... . : : :. . :....... . .:. :. :...
BB0512 KIASWEKFDTNIKELVFKIDNLNKEISLYEKDLANIEERKNDIL--VKGNEKLDLEFSDF
170 180 190 200 210 220
290 300 310 320 330 340
Query TPIVNFEINNFEKEIEKIHQEYEKLYKEAEEAGKNIIDPKRILLNYK-TFNLK--SDVLF
:.:.:....::::. . ::. :: :.. . :... . .: : .: :. .. :
BB0512 LEKVEFNIGKYSKEIESSFNFYENKYKLIENSIELIMESVKNKINEKEDFILNRLNEELQ
230 240 250 260 270 280
350 360 370 380 390 400
Query SKIKSLKSKETIEFKIESERNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIF
.:.:.. . : : . .. ....:...:... ....:: . . .: .:...
BB0512 NKFKDILVYVDDRSK-EIKDKLEDKLVLVDNEISS-MSSSFKDNVYSRINSLEESMRI--
290 300 310 320 330 340
410 420 430 440 450 460
Query KELPKVSIEVLKISSSLIIEKEKIAIILESNIFNTGQKINKAFESSKTKAIDSFVEIEKN
:. : . .: .. ... ...... :.. . ..::... .. .... :.......
BB0512 -EMGKYEEQVDDVFDKF---RSQVELNLKNIYEDYEDKISQVDNNIRERVELSLLDLNSK
350 360 370 380 390
470 480 490 500 510 520
Query SHVVHINHGIGIFRQIKRIKTSSLEKDYIEI--EYAEGEKLFIPIEQTNLIQKYIGSDPK
. :. : . :::....: . :.:. ..... ..: .... : . ...
BB0512 MESVQ----SGAIDFIKRLEDDS-NGIYLEFKGKFGADIEVFSESFKGDINQLKMQLESQ
400 410 420 430 440 450
530 540 550 560 570 580
Query NIKLDKISSKTWIKNKANAKKRIEEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFP
...:. .. X: ..: ...:::.... . ::. .. . :X.. : .:.:
BB0512 LLDVDSNIQEKLIKLNDNLISNFEEINGRFNNNYSNLNDNINAKYTALFESLDSSSSKFE
460 470 480 490 500 510
590 600 610 620 630 640
Query YDETPDQIRAIKEIKEDMMSFKVMDRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSPT
. ... . .......: .:..:
BB0512 NQMESKYKSFTDKLTAGMDEFSLMYGEKFETLSQEATNNYQEFQDLNKKLENEIESFYNM
520 530 540 550 560 570
BB0154 preprotein translocase subunit (secA) {Borrelia burgdorferi}
21.6% identity in 116 aa overlap
530 540 550 560 570 580
Query LDKISSKTWIKNKANAKKRIEEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFPYDE
.:: .. . ..:.:. ..:..:. .
BB0154 KSKRDLKDYLPTLRNINKLERWALLLADEDFSKETEKLKDELKSGNSLENILERAFTLSR
20 30 40 50 60 70
590 600 610 620 630
Query TPDQIRAIKEIKEDMMSFKVM----DRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSP
.... : .:: :. . . .... ..: X:: ...::. . .... ::...
BB0154 EAAR-RRLKERPYDVQIIAGLALHKGKIIEMKTGEGKTLSSVQAAYLNSLTGDGVIIVTV
80 90 100 110 120 130
640 650 660 670 680 690
Query TTILAEQHFNTFKKRFKNFPIKIEVLSRFIKNNAESRILKELKSGKIDIIIGTHKILSKK
.. ::X.. : .: :. . ....:.
BB0154 NDYLAERDSNWMKPVFDLLGVSVGVVLSNMDYELRKAQYAKDITYVTNNELGFDYLRDNM
140 150 160 170 180 190
BB0400 hypothetical protein
17.7% identity in 113 aa overlap
720 730 740 750 760 770
Query FGVKEKEKLKEIRISVDCLALSATPIPRSLHMSLIKLRDISVLKIPPQNRVKIEAYLESF
. .:. . . .: . :.. .: .. ...
BB0400 KSSLKRTDKIRKEALSKLRSMFEFLFSNNSQSDLTYMTEYGVQSSYPNSILKPLNFASNY
190 200 210 220 230 240
780 790 800 810 820 830
Query SELLIKHAIESELSRDGQVFL--VNHNIEELYYLKTLIERLTPYARIAIIHGKLTGEEIE
. ::: .:: .::. .... ::. ... ..... . .: :.... .
BB0400 VDDLIKS------NRDINVFINKIEDTNRELFEIQNKMNNIGMSTESTIAHDEVEVIRSA
250 260 270 280 290 300
840 850 860 870 880 890
Query NIMHNFIK-KAYQILLATTIIENGIDIPNANTIIINNANKFGLAQLYQLKGRVGRGSQKA
: . . . ..::: .....:
BB0400 NKLAIGPRGNHFPILLKNNVVANPQFFGSRERIMQLVWEIEDIQPRLFQKAYRGDLLRVV
310 320 330 340 350 360
BB0355 transcription factor, putative {Myxococcus xanthus}
28.2% identity in 39 aa overlap
440 450 460 470 480 490
Query FNTGQKINKAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKRIKTSSLEKDYIEIE
X:. ::.:....:. . .. :: ::.
BB0355 MAFLLNQSVVYPMHGVGTIKDIRTKEFNGEIIDYYEIH
10 20 30
500 510 520 530 540 550
Query YAEGEKLFIPIEQTNLIQKYIGSDPKNIKLDKISSKTWIKNKANAKKRIEEIADKLIELY
.. ....:X
BB0355 FPFNDMIFMVPVAKVDDFGIRALVSREKVEEVFDVIKEFEGQIDSKKIKDGGHEFYKKSD
40 50 60 70 80 90
BB0828 DNA topoisomerase I (topA) {Synechocystis PCC6803}
17.0% identity in 342 aa overlap
210 220 230 240 250
Query KIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDKTINTLKTKIK-----SVEYKKILE
X :::: ..:...:. :X . .::...
BB0828 NAHEAIRPSEIFIPNETIEIESKTAKEIYKIIWDRTIISGMKDAIKENIKLTFKYKNLIF
370 380 390 400 410 420
260 270 280 290 300
Query ELDFKKETKTEEMFYPLVANTYLGDEIEKHTPIVNFEINNFEKEIEKIHQEY--------
.:.: . .. . .. ....:. ... . .:.: ..... ..... .
BB0828 RSSFTKIIFDGFLKHTKEQDEHLNINFDLIKKGDTFSIVKMKTSEHETKAPFRYTEASLV
430 440 450 460 470 480
310 320 330 340 350 360
Query EKLYKEAEEAGKNIIDPKRILLNYKTFNLK-SDVLFSKIKSLKSKETIE--FKIESERNF
.:. ::. . .. . ..::. .....: ...:...::. . .: : . : ::
BB0828 QKMEKEGIGRPSTYSTIISTLLE-REYAFKLNNTLMPTIKGAAVINLLEKYFPVLIELNF
490 500 510 520 530 540
370 380 390 400 410 420
Query FSNIA--LTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLIIE
::.. :.: .... : . . ..... :.... . .. . .. .. :.: : .
BB0828 TSNMEEKLDKIAIGKLDKIKYLSKFYNGKKGLKDTVMQLEPKIDSSEFRTV-IESQKIEN
550 560 570 580 590 600
430 440 450 460 470 480
Query KEKIAIILESNIFNTGQKIN-KAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKRI
:..:. ... . ... .. .... . ....... . .. ..... .. . ....
BB0828 KNSINYTINIGKYGPYLIFKGHNYSINAKTPLENLYKKDEIEKIINEKELKPNILGVDPL
610 620 630 640 650 660
490 500 510 520 530 540
Query KTSSLEKDYIEIEYAEGEKLFIPIEQTNLIQKYIGSDPKNIKLDKISSKTWIKNKANAKK
..:. . .. :.. .: :.:. :.: ... : ::. :..:. ..: ....
BB0828 --TGLNVIFKNTIYGNIVQL---GEDTHAPQEY-TKKGKPKKLKIIKAKKASTKKIDPEN
670 680 690 700 710
550 560 570 580 590 600
Query RIEEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFPYDETPDQIRAIKEIKEDMMSF
. :.: ::..:
BB0828 ITLELALKLLSLPKPIGKHPQTNEQIIAATGVFGDYIKTESGSIACSLKKDLKAYDITLD
720 730 740 750 760 770
BBK52 protein p23 {Borrelia burgdorferi}
26.8% identity in 56 aa overlap
10 20 30
Query MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGY
.: .. ..:.:: . X: . .:: . .
BBK52 SFKEPELNEIKEGDVLELLAGGYVTWAKSGDLRVLKDKNNNLIEDLRELRYSYIFSPIRF
70 80 90 100 110 120
40 50 60 70 80 90
Query EGFFKAFLIKKIKEYSKTGKIILIVKDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIG
..::. . ..:. :: ::X
BBK52 KTFFSYNYSINDNNYKILGKKAPIVKIIAFESTKEFEKKYEINSLKLNSEESNIDFEQNR
130 140 150 160 170 180
BB0844 hypothetical protein
22.4% identity in 152 aa overlap
90 100 110 120 130 140
Query LNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGIYITVLKSLLSKIPDKNTLLKNIYK
X:: .::...: :::: ... . :.. .
BB0844 MKKKNLSIYMIMLISLLSCNTSDPNELTRKKM
10 20 30
150 160 170 180 190
Query IEKNTNI-----NTADIEKTLITLGYEKTLRVTIPGEFTVKGEIIDIYPFGEQNPIRIAL
.::..X .... .:.... ::. . .... .. .. . .:. :. : :
BB0844 QDKNVKILGFLEKIQADNKEIVEKHIEKKEKQMVQAASVAPINVESNFPYYLQEEIEI--
40 50 60 70 80 90
200 210 220 230 240 250
Query NFDKIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDKTINTLKTKIKSVEYKKILEEL
. ... .. . .. ... :::. : ..: .... . :......: ::.:::
BB0844 KEEELVPNTDEEKKAEKAISDGSLEFAKLVDDENKLKNESAQ-LESSFNNV-YKEILELA
100 110 120 130 140
260 270 280 290 300 310
Query DFKKETKTEEMFYPLVANTYLGDEIEKHTPIVNFEINNFEKEIEKIHQEYEKLYKEAEEA
:.
BB0844 DLIQAEVHVAGRINSYIKKRKTTKEKEYKKREIKNKIEKQALIKLFNQLLEKRGDIENLH
150 160 170 180 190 200
BB0836 excinuclease ABC, subunit B (uvrB) {Escherichia coli}
22.6% identity in 146 aa overlap
60 70 80 90 100 110
Query IVKDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGI
.. :. . ...: .::. . .. :.. :
BB0836 KDFFPNNAVEYFVSYYDYYQPESYVPSKDLFIEKEATINTEIEIKRIRTVTSLAKRRDVI
90 100 110 120 130 140
120 130 140 150 160 170
Query YITVLKSLLSKIPDKNTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVK
.....:. . . . . . :. .. . .:.. .:......: X:.::. ...:..:
BB0836 VVATVSSIYA-LGSPDFFKKSAREFFVGQKISIKEISDIFVELYYERTLMNLERDKFSIK
150 160 170 180 190 200
180 190 200 210 220 230
Query GEIIDIYPFGEQN--PIRIALNFDKIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDK
X.:..:.: .:.. . :: :.::.: :: . ..... :. ... .: ...:. ..
BB0836 GDIVEIWPSSEHGEFAYRICLDFDEIVEIYRVSSFSK-KNLGATNSFTLFAKSYFVIPYE
210 220 230 240 250
240 250 260 270 280 290
Query TINTLKTKIKSVEYKKILEELDFKKETKTEEMFYPLVANTYLGDEIEKHTPIVNFEINNF
BB0836 NVLEAIPKISHDLSLQCQYFKDNGKLVEAERLKQRVEYDLEMLRETGFCSGIENYSKYLS
260 270 280 290 300 310
BB0237 apolipoprotein N-acyltransferase, putative {Haemophilus influenzae}
28.6% identity in 28 aa overlap
140 150 160 170 180 190
Query NTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVKGEIIDIYPFGEQNPI
:..:. . X:.. .: . .::X.....
BB0237 SLNIAAIQLNTDPWLPGNDKKGIRDSIEITEQALKENPKIEFVIWSEGVLTYPFSKEDQH
220 230 240 250 260 270
200 210 220 230 240 250
Query RIALNFDKIEEIKKFNPLTQLKHDNEILEFQILPKKEIIWDDKTINTLKTKIKSVEYKKI
BB0237 FKSSDLHNELKNFIKEHKIPFAIGAPSNLDKAIGIQQNSIYMVEPNLNITNIYSKIFLVP
280 290 300 310 320 330
BB0723 adenylyl cyclase, CyaB-type, putative {Methanococcus jannaschii}
23.5% identity in 132 aa overlap
150 160 170 180 190 200
Query TNINTADIEKTLITLGYEKTLRVTIPGEFTVKGEIIDIYPFGEQNPIRIALNFDKIEEIK
.:.:: . ...:. : .....:.:
BB0723 MFEIESKAFIPTKELKRIIKLANKKFKFIKEEIKTDIYYSNQKKIIRIRKLNTLEKIV
10 20 30 40 50
210 220 230 240 250 260
Query KFNPLTQLKHDNEILEFQILPKKEIIWDDKTINTLKTKIKSVEYKKILEELDFKKETKTE
.:. ... ..:...:. .X:: .. ..::.. : ::....::. ..X. . .:.
BB0723 TFK--KKILDNNNTVEI----NKEIEFKIDSINNFLTLIKELKFKKLYKKIKKSLIYQTN
60 70 80 90 100 110
270 280 290 300 310 320
Query EMFYPLVANTYLGDEIEKHTPIVN-FEINNFEKEIEKIHQEYEKLYKEAEEAGKNIIDPK
.. . . . :: .: .. : : .:. .:::..: ....
BB0723 NLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIDNIINQFGLKENIETRPYSELLSLA
120 130 140 150 160 170
330 340 350 360 370 380
Query RILLNYKTFNLKSDVLFSKIKSLKSKETIEFKIESERNFFSNIALTKEEFENWLKNGFKI
BB0723 NQSKK
BB0569 hypothetical protein
25.0% identity in 84 aa overlap
10 20 30
Query MNIDEELTTILKNNSNLKKMKEFLEQNIFFS
X:.: ..: . .::..: :::.: ::X
BB0569 ISAISARFQNINIASKIEVVKRSELKAMEGNISEMSKIIKEIDSNITKGIEFLDQIIFFL
390 400 410 420 430 440
40 50 60 70 80 90
Query LTGYEGFFKAFLIKKIKEYSKTGKIILIVKDEHTLDKIKNDLQVITNQIFELNYFSPLVY
. ... . : ..: . ..: :... .:.. : . .... ..:.....
BB0569 EKVVKDYDNRFYLEK-NYFNKFKKLFIEIKNDILDIKNIAIDNILSYEVFSIEFMEIFEE
450 460 470 480 490 500
100 110 120 130 140 150
Query KGIGSKSTIFNERIKFLFNFYKKNPGIYITVLKSLLSKIPDKNTLLKNIYKIEKNTNINT
BB0569 IKLEVYNVRNLKNSLLDIDNFLSNMESKINFNLNLELSKVGIQSVEIEDKEFVNRIANRF
510 520 530 540 550 560
BB0633 exodeoxyribonuclease V, beta chain (recB) {Haemophilus influenzae}
17.1% identity in 776 aa overlap
90 100 110 120 130 140
Query ELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGIYITVLKSLLSKIPDKNTLLKNIY
:... ..:...... . .. . .. :
BB0633 KATEEMHTRILKVIENAYSNSKTNEILKEAYEQSKKLFISTINKFALHALNNFQIETENY
60 70 80 90 100 110
150 160 170 180 190 200
Query KIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVKGEIIDIYPFGEQNPIRIALNFDK
. : .. . .:.. :. .. .. :.. ...:. .... ..... :.:...:
BB0633 SKYKPKEKFSKEIDE--IVYDFLRKSDSLIQA-LDIKDYELKVFKSDAKKTEEIVLKIKK
120 130 140 150 160 170
210 220 230 240 250
Query IEEIKKFNPLTQLKHDNEILEFQILPKKEIIWD-DKTINTLKTKIKSVE---YKKILE--
: .. . :.. .... .: .: :.:.: : .:.:..:....:. :.: ..
BB0633 AYERDTTQELGDWLKTQTAFENILLKKEELIKDYNKIIEDLDKMTKDEILSFYNKHIQTG
180 190 200 210 220 230
260 270 280 290 300
Query --ELDFKKETKTEEMFYPLVANTYLGDEIEKHT-PIVNFEINNFEKEIEKIHQEY---EK
:....::... .. .:. :..... :::.: ... .... . . : . ..
BB0633 KLEIEYSKENDIFKIAETLLKNKFFSTLIEKETKKNSKLSPKELKIKNDLICLGINIKHE
240 250 260 270 280 290
310 320 330 340 350 360
Query LYKEAEEAGKNIIDPKRILLNYKTFNLKSDVLFSKIKSLKSKETIE--FKIESERNFFSN
::.... .:: . :. .. .... . . . :..::..::. . :.. .:....
BB0633 KYKSEDNRNKNRNNLKQYVILKVEYKILKYIEKELKKTIKSTNTIDQNYIISNLKNYLKS
300 310 320 330 340 350
370 380 390 400 410 420
Query IALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVSIEVLKISSSLII----EK
..... : .X: .:::. .:... . ::: : ...:... :..X : :
BB0633 ---EDKKLLNAIKNRYKIILIDEAQDLSLIQIEIFKILKTAGIKLIFIADPKQIIYSFRK
360 370 380 390 400
430 440 450 460 470 480
Query EKIAII---LESNIFNTGQKINKAFESSKTKAIDSFVEIEKNSHVVHINHGIGIFRQIKR
..:.. ....: .... . : ..:..: :... .: .: . :...:. . ...
BB0633 ADISFYNKEIKNKINTDARIVLKINHRSSKKLIGPLNKIFNNIYNNAIADEIEKIDFTNS
410 420 430 440 450 460
490 500 510 520 530
Query IKTSSLEKDYIEIEYAEGEKLFIPIEQTNLIQKYIGSDPKNIK----LDKISSKTWIKNK
. . . ... : :. .: : . : ...:. .. ... .:: .::.... :.:
BB0633 LPNQKNDNNKIVINGQEIEGINIITTNTESEEDIYQKTALTIKYLLAYGKIAENNKIRNI
470 480 490 500 510 520
540 550 560 570 580 590
Query ANAKKRI---EEIADKLIELYSKRESIKGIKYPEDNELQLLFESEFPYDETPDQIRAIKE
.. .. .. . .::. :.: :.. : .:. :.. : . :. ...:.
BB0633 KMQDIKVLCRGKNEINLIDKALKKEQIQTNKTQEKFLKTKEFSEIFYIIKCLDRKQSFKT
530 540 550 560 570 580
600 610 620 630 640 650
Query IKEDMMSFKVMDRLLCGDVGFGKTEVAMRAAFKAVMGNKQVIVLSPTTILAEQHFNTFKK
.. . : . . . . .... . ..: . . .. . .:.... . ::.:
BB0633 LNYILSSKILNVPWNLQRILIKQDKICLIEEF--IENIIVLLEKNEITLINAINKITFEK
590 600 610 620 630 640
660 670 680 690 700
Query RFKNFPIKIEVLSRFI-----KNNAESRILKELKSGKIDIIIGTHKILSKKFTCKNLGLI
.. .:. ..: : : .. ..:: : ..... .: .:.:: . ..
BB0633 NLWIKIANITKDQKIIEWAKNKINYKGLLIKEGKLENLKTYETTLEIISKIYHKEQNIQS
650 660 670 680 690 700
710 720 730 740 750 760
Query IIDEEQRFGVKE-----KEKLKEIRISVDCLALSATPIPRSLHMSLIKLRDISVLKIPPQ
.:.. ... ..: .::...:. . ....: ... ...: :... : ... .. .
BB0633 LISTLESLIINEEPEEIEEKINNINNDNESIELMTIHKSKGLGMNIVFLLNTTPIENSNF
710 720 730 740 750 760
770 780 790 800 810 820
Query NRVKIEAYLESFSELLIKHAIESELSRDGQVFLVNHNIEELYYLKTLIERLTPY-ARIAI
. : . : .. . . .. : ... . . . . ....:. . .... . .:.
BB0633 FSKKNQFYKFYQDGKIEYDFFKLEENKKYARLKILSEEKNIFYVGATRAKFALFIIKINS
770 780 790 800 810 820
830 840 850 860 870
Query IHGKLTGE----EIENIMHNFIKKAYQILLATTIIENGIDIPNANTIIINNANKFGLAQL
: .:: . .:..:.:.: ...
BB0633 ITSKLLEIAKIFTIDDIKHDFNIHEFIGQKRFNKKKYNTNVNTKLIPPKPIIKNMFKKEY
830 840 850 860 870 880
BB0707 hypothetical protein
12.7% identity in 55 aa overlap
10 20 30 40 50
Query MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGYEGFFKAFLIKKIKEYSKTGKIILI
^..v :..:^. v .. ... .... . .
BB0707 VKINEYINSIPSSTYKIVSDMFEFYYVFNSLAFFPYKSFFSFFNVDLLDSAENISIVDFE
220 230 240 250 260 270
60 70 80 90 100 110
Query VKDEHTLDKIKNDLQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGIY
: . ....... :. . . ...:.
BB0707 VGFGTSFSSVSKYLNSFFDILYTLKDIEIDEDIVKSIISNYFSISDDISNSEIISREDHI
280 290 300 310 320 330
BB0228 conserved hypothetical protein {Saccharomyces cerevisiae}
20.3% identity in 320 aa overlap
10 20 30
Query MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGYE
:.... .... :.:.: .:.... . .. .
BB0228 INEITNKLEKGIYYFENLIEKYLIFNNHYTLISFIPSHDTEKEMEEEIEKKLMAREIEIK
420 430 440 450 460 470
40 50 60 70 80 90
Query GFFKAFL--IKKIKEYSKTGKIILIVKDEHTLDKIK-NDLQVITNQIFELNYFSPLVYKG
..:: :. ....: . : .: .: .::. ... ..:: .. : ..
BB0228 QNPEEFLQFKKDYNQFKKYQNKKDSKADIAKLPLLKIEDLPKQIEKSLDLNEIKELNLHS
480 490 500 510 520 530
100 110 120 130 140 150
Query IGSKS-TIFNERIKFLFNFYKKNPGIYITVLKSLLSKIPDKNTLLKNIYKIEKNTNINTA
. :: .X:: .. : ..: .:. ::....:. : ....:X :. . .: .
BB0228 FKFKSNNIFNVNLFFKLDFLEKEDYIYLSLFKRALQDLSTKN------YSYININNKIQN
540 550 560 570 580 590
160 170 180 190 200
Query DIEKTLITLGYEKTLRVTIPGEFTVKGEIID---IYPFGEQNPIRIALNFDKIEEIKKFN
..... :. .:.... .: ..:... . .. .:. . : :..::.. : .:...
BB0228 TLGQINISESYDEDIDGNILNSFNISFKSFNNKVKESFELIKEILININFHDYERLKEIT
600 610 620 630 640 650
210 220 230 240 250 260
Query PLTQLKHDNEILEFQILPKKEIIWDDKTINTLKTKIKSVEYKKILEELDFKKETKTEEMF
::.: . : ..:: ... .. ..:: . : .. ... .: ...::..
BB0228 --LSLKNDFKSL---LIPKGHLLAMLRSKSKLKLNEYLKELQNGITGREFWQKAKTDTES
660 670 680 690 700
270 280 290 300 310 320
Query YPLVANTY--LGDEIEKHTPIVNFEINNFEKEIEKIHQEYEKLYKEAEEAGKNIIDPKRI
.::. : ..: .. . .. ..: .. ......:. .: .. ::..
BB0228 LKEIANKLDNLKNKIILKNNLSALIMGNTDDILKNLENEFFNLKESLEESNHYNGLLNLD
710 720 730 740 750 760
330 340 350 360 370 380
Query LLNYKTFNLKSDVLFSKIKSLKSKETIEFKIESERNFFSNIALTKEEFENWLKNGFKIII
BB0228 ANSKALREIIIIQSKVAFNAICFPSYKINDENYPKANFLEHVLRSGIFWEKIRVMGGAYG
770 780 790 800 810 820
BB0536 zinc protease, putative {Haemophilus influenzae}
29.8% identity in 47 aa overlap
290 300 310 320 330 340
Query NFEINNFEKEIEKIHQEYEKLYKEAEEAGKNIIDPKRILLNYKTFNLKSDVLFSKIKSLK
:....: X:: . .: .... .....::
BB0536 LDVELKDKFLLLEDLEVGEPSLMFFKKEIINFVKTKDDLLNAIKKSLLAALFENRFSELK
270 280 290 300 310 320
350 360 370 380 390 400
Query SKETIEFKIESERNFFSNIALTKEEFENWLKNGFKIIIAAESESQKEKLKYIFKELPKVS
. .. .:: :...::X
BB0536 TAGVKQFKNVSNKDFFSFKSDNNTIVAKSISLNFNPDHLNEGIQDFFYELERIRKFGFTQ
330 340 350 360 370 380
BB0329 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (
oppA-2) {Borrelia burgdorferi}
25.4% identity in 63 aa overlap
10 20 30 40 50 60
Query MNIDEELTTILKNNSNLKKMKEFLEQNIFFSLTGYEGFFKAFLIKKIKEYSKTGKIILIV
.X: . : ... . ..::... ::
BB0329 ENEEWTTYLNTKANGNYEIARAGWIGDYADPLTFLSIFTQGYTQFSSHNYSNPEYNELIK
410 420 430 440 450 460
70 80 90 100 110
Query KDEHTLDKIKND--LQVITNQIFELNYFSPLVYKGIGSKSTIFNERIKFLFNFYKKNPGI
:.. .:: :X.. :. .. :.: .. . .:
BB0329 KSDLELDPIKRQDILRQAEEIIIEKDFPIAPIYIYGNSYLFRNDKWTGWNTNILERFDLS
470 480 490 500 510 520
120 130 140 150 160 170
Query YITVLKSLLSKIPDKNTLLKNIYKIEKNTNINTADIEKTLITLGYEKTLRVTIPGEFTVK
BB0329 QLKLKNK
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